Protein Alignment CG11951 and CG42335

DIOPT Version :10

• Sequence 1: NP_001350853.2
• Gene: CG11951 / 43463
• FlyBaseID: FBgn0039656
• Length: 842
• Species: Drosophila melanogaster
• Sequence 2: NP_732655.3
• Gene: CG42335 / 42558
• FlyBaseID: FBgn0259237
• Length: 924
• Species: Drosophila melanogaster
• Alignment Length: 934
• Identity: 249/934 - (26%)
• Similarity: 437/934 - (46%)
• Gaps: 99/934 - (10%)

  Fly    25 FRLPTALRPQSYDVRILTQLENPDDFHFNGTVKIQIEVL--QNTHNITLHSKDLTIDDTEITLSQ 87
            :||..::.|..|::.|.....:.:...|:|.|.|.:.|:  .....|.||:.  |:|.||..|..
  Fly    25 YRLEGSVVPSHYNLTIGVLRNSVEPTIFDGEVSITLRVVGTLEVQQIILHAD--TLDITECWLLD 87

  Fly    88 IGGEETTENCITSTAVNPTHDFYILNTCKELLAGQFYELSLPFSAKLQDQLAGYYRSSYVNTVAN 152
            ..|.:.....|:............:...:....|:.|.|...::..::..:||::.:|||....|
  Fly    88 AAGAQVEAIDISRLIYEAATQQVRVPLTEAAQPGKNYTLGFKYTGHIRTDMAGFFSASYVERDTN 152

  Fly   153 ETRWISVTQFEPAAARLAFPCFDEPGYKASFAITLGYHKKYTGLSNMPVNETR--PHESIPDYVW 215
            .|||:::||.:...|||..||||||..||.|.:.:.....|..::|..:.||:  ..:...|:
  Fly   153 VTRWLALTQMQRINARLVLPCFDEPALKAQFQLQIVRPNGYQSIANTKLKETKALSQDRFVDH-- 215

  Fly   216 TSFEESLPMSTYLVAYSLNDFSHKPSTLPNGTLFRTWARPNAIDQCDYAAELGPKVLKYYEELFG 280
              |:|:..|||||:|:.:.::|.:    .|.:.|....||...|..:::..:|.:|:..|.|||
  Fly   216 --FKETPVMSTYLLAFMVANYSAR----GNESEFAVLTRPEFYDNTEFSYHVGQQVVSAYGELF- 273

  Fly   281 IKFPLPK-----VDQIAVPDFSAGAMENWGLVTFAESTLLYSPEYSSQEAKQETA-NIVAHELAH 339
             :.|..:     :...:.|.|....||||||:.:::..|:..|.||...:.:|.| .|:|||.:|
  Fly   274 -QSPYAELGNDVLQYASSPRFPHNGMENWGLIIYSDDVLIQEPGYSDDWSDKEFAIRIIAHETSH 337

  Fly   340 QWFGNLVTMKWWTDLWLNEGFATYVASLCVEDIHPQWRTLQLESMSNLLTIFRKDSLESSHPISR 404
            .|||:.||..||:..||||.||.|........::|.:...:...:..:..||..|:...:.|::.
  Fly   338 MWFGDSVTFSWWSYFWLNEAFARYYEYFMAHQLYPDYHLDEQFVVRQMQLIFGTDAQNGTQPMTS 402

  Fly   405 P---IEMTSQISESFDEISYQKGSSVIRMMHLFLGEEAFRTGLKSYLEKYTYKNAEQDNLWESLT 466
            |   |:..|||:..|..|:|.||:.::||....:|.|.|.|.::|||::|...|....||:..|.
  Fly   403 PESEIQTPSQIAYKFSGIAYAKGACIVRMWRNLMGAENFDTAIRSYLQQYHLTNTVPYNLFYHLF 467

  Fly   467 QAAHKTGSLPKDYNIKTIMDSWTLQTGYPVINVTRDYTSRTAKLSQERYLLNTDVSRAHKGCWWV 531
            :...|.    :|.::...:..:|.|.|||:|.|.....::...:.|.|:|||.|........:.|
  Fly   468 EHWPKN----QDVDLVDFLTDYTEQVGYPMIIVKALQGNKVVTVEQSRFLLNKDDGSNATLKYTV 528

  Fly   532 PLSYTNQEEKDFNNTAPKEWMECTETGESVPKTIH----DLPGPDQWVIFNNQLSAPYKVNYDAQ 592
            |:::|...|:||.|..|.:::.         ||::    |...|..|::||.:.|...:|.||..
  Fly   529 PITFTTNLERDFYNLTPYKYLH---------KTVNVLWLDFTSPIDWILFNLRQSNYQRVFYDDT 584

  Fly   593 NWKLLIETLNSEDYHSIHVVNRAQLIDDVLYFAWTGEQDYEIALQVISYLERERELLPWKSAFDN 657
            ..:.|:..:::.::..|.|.||||:|||:..||.....||....:.:.||.:|.|.:||.:.::|
  Fly   585 LREGLLLAISATNHSGIPVENRAQIIDDLFNFAQAQYVDYADVFRFLEYLAKEVEYVPWYAVYEN 649

  Fly   658 LQFVSGIL--RQTPNFRFFKNFTRRLITPIYEHLN-GIN--DTVASEEQQDKTILKAIVADWACS 717
            |..|:..|  .|.|:||.:.:   .:...::|.|. |.|  ||......::|.|      .|.|.
  Fly   650 LNTVAKRLTPEQLPDFRIYLS---SITAAVFEKLGVGWNAQDTPLDVANRNKLI------KWLCR 705

  Fly   718 FEVSDCVTQALSFYRSWRSEANPDEVNPVPLGIRGVVYCTAIKHGCD-EDWDFLWTRYQKANVAT 781
            ::.|:|..:....:.:.....:||        .|...||.|  .|.| ..:..||.:|...|..:
  Fly   706 YQASNCRPKVNVQFVTGHEVPSPD--------YRETFYCAA--SGADYNSYTMLWGQYYLENRTS 760

  Fly   782 EKQIILDSLGCSQEVWVLQRYLERNFDGMGDIRKQDSTSVFQAIADSEVGFLLAKKYLMDNVDSI 846
            ||.::..::.|:::       .|.::..|       ..|..:::...::|  :|:.| .:|.|.:
  Fly   761 EKNMLWAAISCTRD-------YETHYHKM-------IISGTESVEQKKIG--IARMY-EENPDLV 808

  Fly   847 SKFYHPQSESMSEL-------------LPPLSEQIFTQRDYDEFM-NFMASSKDQLKDIEQTISQ 897
            ...:...:|::.||             :..::| .||.|:..:.: .|..|:.....:.|:.:|:
  Fly   809 QAIFEMITENIMELAYNFQSWSDTAEVINDMAE-YFTTREQQQLLKEFYYSNHQFFGESEELLSK 872

  Fly   898 SLETMLINVQWKERNYERFTRAIS 921
            ||.|:..|:.|.|.:.|...:.::
  Fly   873 SLVTVEKNLNWAETHLEGLVKYLA 896

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11951	NP_001350853.2	M1_APN-Q_like	35..490	CDD:341064	133/467 (28%)
		ERAP1_C	574..902	CDD:463368	83/347 (24%)
CG42335	NP_732655.3	M1_APN-Q_like	34..487	CDD:341064	133/468 (28%)
		ERAP1_C	566..878	CDD:463368	84/348 (24%)