Protein Alignment CG11951 and Psa

DIOPT Version :10

• Sequence 1: NP_001350853.2
• Gene: CG11951 / 43463
• FlyBaseID: FBgn0039656
• Length: 842
• Species: Drosophila melanogaster
• Sequence 2: NP_728614.1
• Gene: Psa / 38175
• FlyBaseID: FBgn0261243
• Length: 1075
• Species: Drosophila melanogaster
• Alignment Length: 912
• Identity: 290/912 - (31%)
• Similarity: 468/912 - (51%)
• Gaps: 85/912 - (9%)

  Fly    26 RLPTALRPQSYDVRILTQLENPDDFHFNGTVKIQIEVLQNTHNITLHSKDLTIDDTEI--TLSQI 88
            ||||.:.|:.|::.:...|:   :|.|.|...:|:.|.:.|..|||::.|:.:|..|:  ..|::
  Fly   218 RLPTNVVPRHYELLLQPNLK---EFTFTGKTVVQVNVKEPTTQITLNALDIVLDSVELHFECSKL 279

  Fly    89 GGEETTENCITSTAVNPTHDFYILNTCKELLAGQFYELSLPFSAKLQDQLAGYYRSSYVNTVANE 153
            ..|:...:....||.        |...:|:.|.....|.:.|:.:|.|::.|:|||.|... ..|
  Fly   280 KPEKIVYSAENETAT--------LEFAQEIPAETQGVLHMSFTGELNDKMKGFYRSKYFGP-NGE 335

  Fly   154 TRWISVTQFEPAAARLAFPCFDEPGYKASFAITLGYHKKYTGLSNMPVNETRPHESIPDYV-WTS 217
            .|:..|||||...||..|||:|||..||:|.|||...|....||||||.:   .:|:||.: ...
  Fly   336 ERFAGVTQFEATDARRCFPCWDEPAIKATFDITLVVPKDRVALSNMPVIK---EDSLPDGLRRVR 397

  Fly   218 FEESLPMSTYLVAYSLNDFSHKPSTLPNGTLFRTWARPNAIDQCDYAAELGPKVLKYYEELFGIK 282
            |:.:..|||||||..:.::.:......:|.|.|.:......:|..:|.|:..|||.||::.|.|.
  Fly   398 FDRTPIMSTYLVAVVVGEYDYVEGKSDDGVLVRVFTPVGKREQGTFALEVATKVLPYYKDYFNIA 462

  Fly   283 FPLPKVDQIAVPDFSAGAMENWGLVTFAESTLLYSPEYSSQEAKQETANIVAHELAHQWFGNLVT 347
            :||||:|.||:.||||||||||||||:.|:.:|..|:.:|...||..|..|.||:||||||||||
  Fly   463 YPLPKMDLIAISDFSAGAMENWGLVTYRETFVLVDPKNTSLMRKQSIALTVGHEIAHQWFGNLVT 527

  Fly   348 MKWWTDLWLNEGFATYVASLCVEDIHPQ---WRTLQLESMSNLLTIFRKDSLESSHPISRPIEMT 409
            |:|||.||||||:|::|..|||..:.|:   |.....:..:..|.:   |||::||||..|:...
  Fly   528 MEWWTHLWLNEGYASFVEFLCVHHLFPEYDIWTQFVTDMYTRALEL---DSLKNSHPIEVPVGHP 589

  Fly   410 SQISESFDEISYQKGSSVIRMMHLFLGEEAFRTGLKSYLEKYTYKNAEQDNLWESLTQAAHKTGS 474
            |:|.|.||||||.||:|||||:|.::||:.||.|:..||.::.|.|...::||.:|.:|:.|
  Fly   590 SEIDEIFDEISYNKGASVIRMLHDYIGEDTFRKGMNLYLTRHQYGNTCTEDLWAALQEASSK--- 651

  Fly   475 LPKDYNIKTIMDSWTLQTGYPVINVTRDYTSRTAKLSQ-ERYLLNTDVSRAHKGCWW-VPLSYTN 537
                 |:..:|.|||...|:||::|..:.||:..:|.: ::.....|.|:|.:.|.| ||:|.:.
  Fly   652 -----NVSDVMTSWTQHKGFPVVSVESEQTSKNQRLLRLKQCKFTADGSQADENCLWVVPISVST 711

  Fly   538 QEE-----KDFNNTAPKEWMECTETGESVPKTIHDLPGPDQWVIFNNQLSAPYKVNYDAQNWKLL 597
            .:.     |.|  ...|..||.|          .|....|.|:..|......|:..|..:   :|
  Fly   712 SKNPTGIAKTF--LLDKSSMEVT----------LDNVDEDDWIKINPGTVGYYRTRYSQE---ML 761

  Fly   598 IETLNSEDYHSIHVVNRAQLIDDVLYFAWTGEQDYEIALQVISYLERERELLPWKSAFDNLQFVS 662
            .:.:.:.:...:..::|..||||:......|.......|.::.....|.....|.:..::|..:.
  Fly   762 EQLMPAVEKMELPPLDRLGLIDDMFAMVQAGHASTADVLALVDSYRNETNYTVWTAITNSLTNLH 826

  Fly   663 GILRQTPNFRFFKNFTRRLITPI-----YEHLNGINDTVASEEQQDKTILKAIVADWACSFEVSD 722
            .::..|.....|..|.|.|..|:     :|..:|        |....|:|:::|.....||..||
  Fly   827 ILISHTDLMEDFHRFGRNLYEPVAYRLGWEPRDG--------ENHLDTLLRSLVLTRLVSFRSSD 883

  Fly   723 CVTQA-LSFYRSWRSEANPDEVNPVPLGIRGVVYCTAIKHGCDEDWDFLWTRYQKANVATEKQII 786
            .:.:| :.|    |...|..|:  :|..:|...|...::.|.::.::.:...|:..::..|:..|
  Fly   884 TIEEAKIRF----RRHVNGTEL--LPADLRTTCYKAVLQDGDEKIFNEMLDLYRATDLHEEQDRI 942

  Fly   787 LDSLGCSQEVWVLQRYLERNFDGMGDIRKQDSTSVFQAIADSEVGFLLAKKYLMDNVDSISKFYH 851
            ..:|||..::.:|:|.::  |....::|.|||..|..|:|.:..|..:|.::..:|...:.:.|.
  Fly   943 SRALGCCGDLKLLRRVID--FAMSSEVRAQDSVFVIVAVAINPKGRDMAWEFFKENNKQLLERYQ 1005

  Fly   852 PQSESMSELLPPLSEQIFTQ---RDYDEFMNFMASSKDQLKDIEQTISQSLETMLINVQWKERNY 913
             ....:|.|:..|.|...::   ::.:||:..     :|:...|:|:||::||:.:|..|.:|:.
  Fly  1006 -GGFLLSRLIKYLIENFASEERAKEVEEFLQV-----NQIPGCERTVSQAVETIRLNAAWLQRDR 1064

  Fly   914 ER 915
            |:
  Fly  1065 EQ 1066

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11951	NP_001350853.2	M1_APN-Q_like	35..490	CDD:341064	184/460 (40%)
		ERAP1_C	574..902	CDD:463368	72/336 (21%)
Psa	NP_728614.1	M1_APN-Q_like	227..662	CDD:341064	184/460 (40%)
		ERAP1_C	741..1055	CDD:463368	73/338 (22%)