Protein Alignment CG11951 and CG3502

DIOPT Version :10

• Sequence 1: NP_001350853.2
• Gene: CG11951 / 43463
• FlyBaseID: FBgn0039656
• Length: 842
• Species: Drosophila melanogaster
• Sequence 2: NP_611781.3
• Gene: CG3502 / 37695
• FlyBaseID: FBgn0046253
• Length: 912
• Species: Drosophila melanogaster
• Alignment Length: 950
• Identity: 334/950 - (35%)
• Similarity: 515/950 - (54%)
• Gaps: 81/950 - (8%)

  Fly     4 VFLILAALGLSFAGEGSTYDHFRLPTALRPQSYDVRILTQLENPDDFHFNGTVKIQIEVLQNTHN 68
            :||||.      ....:.|:.:|||.::.|..|::||||.| |..|..|.|:|.|.:...:.|.|
  Fly    13 IFLILV------PSIRAVYEDYRLPRSVEPLHYNLRILTHL-NSTDQRFEGSVTIDLLARETTKN 70

  Fly    69 ITLHSKDLTIDDTEITLSQIGGEETTENCITSTAVNPTHDFYILNTCKELLAGQFYELSLPFSAK 133
            ||||:..|.||:..  .|.:.|:|  :..:....||..|:||||:..:||:..|.|:|.:.|.|.
  Fly    71 ITLHAAYLKIDENR--TSVVSGQE--KFGVNRIEVNEVHNFYILHLGRELVKDQIYKLEMHFKAG 131

  Fly   134 LQDQLAGYYRSSYVNTVANETRWISVTQFEPAAARLAFPCFDEPGYKASFAITLGYHKKYTGLSN 198
            |.|..:|||:|:|.:.|..|...::||||.|..||.||||||||.:||:|.|||||||||.|||.
  Fly   132 LNDSQSGYYKSNYTDIVTKEVHHLAVTQFSPTFARQAFPCFDEPSWKATFNITLGYHKKYMGLSG 196

  Fly   199 MPVNETRPHESIPDYVWTSFEESLPMSTYLVAYSLNDFSH---KPSTLPNGTLFRTWARPNAIDQ 260
            |||...:.|:|:.:|||...:..|..||||||::::|..:   :.|...|..:||.|.:|..:.|
  Fly   197 MPVLRCQDHDSLTNYVWCDHDTLLRTSTYLVAFAVHDLENAATEESKTSNRVIFRNWMQPKLLGQ 261

  Fly   261 CDYAAELGPKVLKYYEELFGIKFPLPKVDQIAVPDFSAGAMENWGLVTFAESTLLYSPEYSSQEA 325
            ...:.|:.||:|.:||.||.|.|||.||||:.||.....|||||||||:.|..|..:.....|:.
  Fly   262 EMISMEIAPKLLSFYENLFQINFPLAKVDQLTVPTHRFTAMENWGLVTYNEERLPQNQGDYPQKQ 326

  Fly   326 KQETANIVAHELAHQWFGNLVTMKWWTDLWLNEGFATYVASLCVEDIHPQWRTLQLESMSNLLTI 390
            |..||..||||.|||||||||||.||.||||.||.:||...|.::.:.|:||..:.....:|...
  Fly   327 KDSTAFTVAHEYAHQWFGNLVTMNWWNDLWLKEGPSTYFGYLALDSLQPEWRRGERFISRDLANF 391

  Fly   391 FRKDSLESSHPISRPIEMTSQISESFDEISYQKGSSVIRMMHLFLGEEAFRTGLKSYLEKYTYKN 455
            |.|||..:...||:.::..:::...|.|..|:|||..|||:|..:|||||..|::|:||::::.|
  Fly   392 FSKDSNATVPAISKDVKNPAEVLGQFTEYVYEKGSLTIRMLHKLVGEEAFFHGIRSFLERFSFGN 456

  Fly   456 AEQDNLWESLTQAAHKTGSLPKDYNIKTIMDSWTLQTGYPVINVTRDYTSRTAKLSQERYLLNTD 520
            ..|.:||.||..||.|...:..|:|:...|||||||.|||::.:.|:|.:....|:|.|:.....
  Fly   457 VAQADLWNSLQMAALKNQVISSDFNLSRAMDSWTLQGGYPLVTLIRNYKTGEVTLNQSRFFQEHG 521

  Fly   521 VSRAHKGCWWVPLSYTNQEEKDFNNTAPKEWMECTETGESVPKTIHDLPGPDQWVIFNNQLSAPY 585
            :.:| ..||||||.:..|...|||.|.|:.|:|| .....|.| :.|....|:|||.|.|::..:
  Fly   522 IEKA-SSCWWVPLRFVRQNLPDFNQTTPQFWLEC-PLNTKVLK-LPDHLSTDEWVILNPQVATIF 583

  Fly   586 KVNYDAQNWKLLIETL-NSEDYHSIHVVNRAQLIDDVLYFAWTGEQDYEIALQVISYLERERELL 649
            :||||..||:|:||:| |..:...||.:|:|||:||::..|......|:.|..::.||::|::.|
  Fly   584 RVNYDEHNWRLIIESLRNDPNSGGIHKLNKAQLLDDLMALAAVRLHKYDKAFDLLEYLKKEQDFL 648

  Fly   650 PWKSAFDNLQFVSGILRQTPNFRFFKNFTRRLITPIYEH---LNGINDTVASEEQQDKTILKAI- 710
            ||:.|...|..: |.|........|||:.::|:.|:|..   |:||.:.        |..:|.|
  Fly   649 PWQRAIGILNRL-GALLNVAEANKFKNYMQKLLLPLYNRFPKLSGIREA--------KPAIKDIP 704

  Fly   711 ----VADWACSFEVSDCVTQALSFYRSWRSEANPDEVNPVPLGIRGVVYCTAIKHGCDEDWDFLW 771
                ....||.:.|:||..||.....:.|:|...:    :|...:.|.||:.:..|.|.::..::
  Fly   705 FAHFAYSQACRYHVADCTDQAKILAITHRTEGQLE----LPSDFQKVAYCSLLDEGGDAEFLEVF 765

  Fly   772 TRYQKANVATEKQIILDSLGCSQEVWVLQRYLERNFDG----MGDIRKQDSTSVFQAIADSEVGF 832
            ..:|.:...::::|:..:|||.:.....:::|....:.    :||.                  :
  Fly   766 GLFQNSTNGSQRRILASALGCVRNFGNFEQFLNYTLESDEKLLGDC------------------Y 812

  Fly   833 LLAKK--------------YLMDNVDSISKFYHPQSESMSELLPPLSEQIFTQRDYDEFMNFMAS 883
            :||.|              |::.:...:.:.:  :.:.::.||..|::.:.:..:.|.    :.:
  Fly   813 MLAVKSALNREPLVSPTANYIISHAKKLGEKF--KKKELTGLLLSLAQNLRSTEEIDR----LKA 871

  Fly   884 SKDQLKDIEQTISQSLETMLINVQWKERNYERFTRAISKH 923
            ..:.||:.|:.:.::|....:|.:|::.....|..||.||
  Fly   872 QLEDLKEFEEPLKKALYQGKMNQKWQKDCSSDFIEAIEKH 911

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11951	NP_001350853.2	M1_APN-Q_like	35..490	CDD:341064	203/457 (44%)
		ERAP1_C	574..902	CDD:463368	84/354 (24%)
CG3502	NP_611781.3	M1_APN-Q_like	37..491	CDD:341064	203/458 (44%)
		ERAP1_C	572..887	CDD:463368	83/351 (24%)