Protein Alignment CG11951 and LOC3290884

DIOPT Version :10

• Sequence 1: NP_001350853.2
• Gene: CG11951 / 43463
• FlyBaseID: FBgn0039656
• Length: 842
• Species: Drosophila melanogaster
• Sequence 2: XP_061503389.1
• Gene: LOC3290884 / 3290884
• VectorBaseID: AGAMI1_007830
• Length: 956
• Species: Anopheles gambiae
• Alignment Length: 945
• Identity: 280/945 - (29%)
• Similarity: 470/945 - (49%)
• Gaps: 81/945 - (8%)

  Fly     6 LILAALGLSFAGEGST----YDHFR--LPTALRPQSYDVRILTQLENPDDFHFNGTVKIQIEVLQ 64
            ||||:..:....:.||    :|..|  ||....|.:|:  :...:.|.|.:.:||||:|......
Mosquito    15 LILASAPVEIVEKVSTSRDAHDDSRYLLPKVSEPINYN--LFLDITNYDFYSYNGTVEITFRYTG 77

  Fly    65 NTHNITLHSKDLTIDDTEITLSQIGGEETTENCITSTAVNPTHDFYILNTCKELLAGQFYELSLP 129
            :.::..|:|..|.|....|   ::.|.:.|:..:.:.......:.........|..|:.|::::.
Mosquito    78 DQNHFYLNSDGLVIATESI---KVTGPDGTDVPVANVIYMEEFEQIYFGFRDRLQTGEQYKIAIS 139

  Fly   130 FSAKLQDQLAGYYRSSYVNTVANETRWISVTQFEPAAARLAFPCFDEPGYKASFAITLGYHKKYT 194
            |...:..:|.|.|||||  ...|.||:::.|.||...||..|||:|||.|||:|.:.:.:..:|.
Mosquito   140 FLNNIGTELKGLYRSSY--KAGNTTRYLATTHFESTYARSVFPCYDEPSYKATFNVKIRHRSEYR 202

  Fly   195 GLSNMP-VNETRPHESIPDYVWTSFEESLPMSTYLVAYSLNDF---SHKPSTLPNGTLFRTWARP 255
            .||||| :|..    ::.||..|:|:.:..|||||:|:.::||   ||:...      ||.:|..
Mosquito   203 ALSNMPAINSV----TVGDYTETTFDTTPLMSTYLLAFVISDFKTLSHESDR------FRVFAAE 257

  Fly   256 NAIDQCDYAAELGPKVLKYYEELFGIKFPLPKVDQIAVPDFSAGAMENWGLVTFAESTLLYSPEY 320
            :.:....||.|.....|:..|..||.::.|||||.||:|||:.||||||||:||.|..|:|....
Mosquito   258 SKVAHTGYALEFLGNSLRTLENFFGRQYQLPKVDLIAIPDFAMGAMENWGLITFREQYLIYEEGV 322

  Fly   321 SSQEAKQETANIVAHELAHQWFGNLVTMKWWTDLWLNEGFATYVASLCVEDIHPQWRTLQLESMS 385
            ::...||..|:::.|||.|.||||.||.:|||.|||:||||.|........:.|.|...|...::
Mosquito   323 TTARTKQNIADLITHELTHMWFGNEVTPEWWTYLWLSEGFARYFEYYITSQLEPTWNLWQQFIVN 387

  Fly   386 NLLTIFRKDSLESSHPISRPIEMTSQISESFDEISYQKGSSVIRMMHLFLGEEAFRTGLKSYLEK 450
            |:.:...:|...::..:|......:.:::.||.:.|.|.:|||||:...:|.:.||..|..||..
Mosquito   388 NVHSALSQDCNSNNRMMSYYATNPAVLNDLFDYVVYAKSASVIRMIQNVIGFDTFRQSLNDYLRS 452

  Fly   451 YTYKNAEQDNLWESLTQAAHKTGSLPKDYNIKTIMDSWTLQTGYPVINVTRDYTSRTAKLSQERY 515
            .:|.......|:.|:.:  .:|..||.  :::.|.:||....||||:.|:.|.|:||...||:|:
Mosquito   453 RSYLTTRPQYLYTSIEK--FRTVDLPA--SVEVIFESWANTPGYPVVTVSIDRTTRTLTASQKRF 513

  Fly   516 LLNTDVSRAHKG-CWWVPLSYTNQ--EEKDFNNTAPKEWMECTETGESVPKTIHDLPGPDQWVIF 577
            .:..::....:. .:::|::|.:.  ...||.:|.|..|:    |.:....|: .|....:||:.
Mosquito   514 WMPNEIDTPPQNMLFYIPVNYGSNVPTSTDFEDTTPTFWL----TPQDPTATV-TLEAGVEWVVV 573

  Fly   578 NNQLSAPYKVNYDAQNWKLLIETLNSEDYH-SIHVVNRAQLIDDVLYFAWTGEQDYEIALQVISY 641
            |.|.:..|:||||.::|..|||.|||:.:. .:.|:|||||:|||...|..||..|::||.::.|
Mosquito   574 NKQQTGYYRVNYDDESWHKLIEVLNSDQFEDQLPVINRAQLVDDVANLARAGEVGYDVALSLMQY 638

  Fly   642 LERERELLPWKSAFDNLQFVSGILRQTPNFRFFKNFTRRLITPIYEH--LNGINDTVASEEQQDK 704
            ||||.|.:||.:|::.|.::..:......:..|:.|.|.:...:||:  |.|..|.::...:.:.
Mosquito   639 LERETEYIPWATAYNALLYLDRMFSSHEEYSRFETFLRTITGCMYENILLTGPMDQISRLHRGNT 703

  Fly   705 TILKAIVADWACSFEVSDCVTQALSFYRSWRSEANPDEVNPVPLGIRGVVYCTAIKH-----GCD 764
            ..|       ||...|..|:..|    .:..::|..|....:|..::..|:|...|:     ...
Mosquito   704 VYL-------ACYSGVKKCLDDA----HALANKAVQDSSFTIPEEVQASVFCALHKYPSATLNAQ 757

  Fly   765 EDWDFLWTRY-QKANVATEKQII---LDSLGCSQEVWVLQRY---LERNFDGMGDIRKQDSTSVF 822
            .|   |:.:| ..||...:..:|   |.|:||::...:::.|   |..|:.|:.....|.|....
Mosquito   758 TD---LFEKYVTSANSPEDLDMINRFLASVGCARNETIMEYYLTLLAYNYPGLPVTAGQRSQIYL 819

  Fly   823 QAIADSEVGFLLAKKYLMDNVDSISKFYHPQSESMSELLPPLSEQIFTQRDYDEFMNFMASSKDQ 887
            ..|..|......|.:||.::..:::...    .|::.:...|..:|.|:..::...|.:    |:
Mosquito   820 GLINGSPGTRQAALQYLYEHFSTVTYLL----TSVTPIFTELGNRINTRLQHEVLKNIV----DE 876

  Fly   888 LKDIEQTISQ-SLETMLI----NVQWKERNYERFT 917
            .:.:..|.:: :.:..|:    |::|.|::.|..|
Mosquito   877 YRHMLTTAAKAAADAALVKAEQNIRWIEKHAESIT 911

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11951	NP_001350853.2	M1_APN-Q_like	35..490	CDD:341064	152/458 (33%)
		ERAP1_C	574..902	CDD:463368	89/343 (26%)
LOC3290884	XP_061503389.1	None