Protein Alignment CG11951 and anpepb.1

DIOPT Version :10

• Sequence 1: NP_001350853.2
• Gene: CG11951 / 43463
• FlyBaseID: FBgn0039656
• Length: 842
• Species: Drosophila melanogaster
• Sequence 2: NP_001082794.1
• Gene: anpepb.1 / 322533
• ZFINID: ZDB-GENE-030131-1253
• Length: 965
• Species: Danio rerio
• Alignment Length: 915
• Identity: 329/915 - (35%)
• Similarity: 499/915 - (54%)
• Gaps: 61/915 - (6%)

  Fly    22 YDHFRLPTALRPQSYDVRILTQLE-NPDDFH-FNGTVKIQIEVLQNTHNITLHSKDLTIDDTEIT 84
            :|.:|||..|.|::|.|.:..:|: |.:..: |.|...:....::||..|.:||..|||.|: .|
Zfish    74 WDQWRLPQTLSPETYKVTLWPRLQKNAEGLYIFTGDSSVVFRCVENTDLILIHSNKLTIKDS-TT 137

  Fly    85 LSQIGGEETTENCITSTAVNPTHDFYILNTCKELLAGQFYELSLPFSAKLQDQLAGYYRSSYV-- 147
            |..:||.....  |.||.:.|...:..:...:||.||:.|||...|..:|.|.|.|:|||.|.
Zfish   138 LKALGGNPAPN--IVSTKMYPKTQYMAIWLDRELTAGESYELYTEFVGELSDDLGGFYRSEYYDE 200

  Fly   148 NTVANETRWISVTQFEPAAARLAFPCFDEPGYKASFAITLGYHKKYTGLSNMPVNETRPHESIP- 211
            |.|   .:.::.||.:...||.||||||||..||.|.|.|.:......|||..|     .|.||
Zfish   201 NGV---LKVVATTQMQATDARKAFPCFDEPAMKAVFNIVLLHDPGTVALSNGVV-----IEEIPV 257

  Fly   212 -----DYVWTSFEESLPMSTYLVAYSLNDFSHKPSTLPNGTLFRTWARPNAID--QCDYAAELGP 269
                 ....|:|..:..|||||:|:.:::|::....| :....|.:||..|||  |.:||..:..
Zfish   258 TVDGISLTKTTFAPTEKMSTYLLAFIVSEFTYIEQKL-DDLQIRIFARKEAIDANQGEYALSVTG 321

  Fly   270 KVLKYYEELFGIKFPLPKVDQIAVPDFSAGAMENWGLVTFAESTLLYSPEYSSQEAKQETANIVA 334
            |:|:::||.:...:||||.||||:|||:|||||||||:|:.|:.|||..|.||...|:....::|
Zfish   322 KILRFFEEYYNSSYPLPKSDQIALPDFNAGAMENWGLITYRETALLYDEEMSSNGNKERVVTVIA 386

  Fly   335 HELAHQWFGNLVTMKWWTDLWLNEGFATYVASLCVEDIHPQWRTLQLESMSNLLTIFRKDSLESS 399
            |||||||||||||::||.|||||||||:||..|..::..|.|....|..::::..:|..|:|.||
Zfish   387 HELAHQWFGNLVTIRWWNDLWLNEGFASYVEYLGADEAEPLWNIKDLIVLNDVHRVFAIDALASS 451

  Fly   400 HPIS---RPIEMTSQISESFDEISYQKGSSVIRMMHLFLGEEAFRTGLKSYLEKYTYKNAEQDNL 461
            ||:|   ..::...||||.||.|||.||:||:||:..||.|:.|..||::|||.:.:.|....:|
Zfish   452 HPLSSKEEDVQRPEQISEVFDTISYSKGASVLRMLSNFLSEDVFTQGLRTYLEHFKFNNTVYTDL 516

  Fly   462 WESLTQAAHKTGS-LPKDYNIKTIMDSWTLQTGYPVINVTRDYTSRTAKLSQERYLLNTDVSRAH 525
            |:.|..|..:||: ||:  ::|.|||.|.||.|:||:.:    .:.|.::|||.:||:.:.....
Zfish   517 WDHLQMAVDETGTELPR--SVKDIMDRWVLQMGFPVVTI----NTVTGQISQEHFLLDPETKPEP 575

  Fly   526 KGC---WWVPLSYTNQEEKDFNNTAPKEWMECTETGESVPKTIHDLPGPDQWVIFNNQLSAPYKV 587
            ...   |:||:::|..|.     ..|:.|:....|.....||     ..::||:.|......|:|
Zfish   576 SEFNYEWFVPITWTKNEA-----IKPQYWLLQKNTQFDDMKT-----NANEWVLANINTVGYYRV 630

  Fly   588 NYDAQNWKLLIETLNSEDYHSIHVVNRAQLIDDVLYFAWTGEQDYEIALQVISYLERERELLPWK 652
            |||.|||:.|:..|.: ...||.|:||||||||....|..|.....:||:...:|:.|.|.:||:
Zfish   631 NYDEQNWERLLNALQT-SRESIPVINRAQLIDDAFNLAKAGIIKTTLALRTTEFLDVETEYMPWQ 694

  Fly   653 SAFDNLQFVSGILRQTPNFRFFKNFTRRLITPIYEHLNGINDTVASEEQQDKTILKAIVADWACS 717
            ||.:||.:...:..::..:...:.:.|:.:||::|:...:.|.....:...:...:......|||
Zfish   695 SALNNLDYFYLMFDRSEVYGHMQAYIRKQVTPLFEYFTELTDWQGVPDNHTEQYNQVNALRVACS 759

  Fly   718 FEVSDCVTQALSFYRSWRSEANPDEVNPVPLGIRGVVYCTAIKHGCDEDWDFLWTRYQKANVATE 782
            ..:.:|.....|::..|   .|.::|||:...:|..|||:||..|..|:|:|.|..::|.:||:|
Zfish   760 IGLKNCTDLVTSWFGEW---MNNEDVNPIHANLRSTVYCSAIAAGGAEEWEFAWKMFEKTSVASE 821

  Fly   783 KQIILDSLGCSQEVWVLQRYLERNFDGMGDIRKQDSTSVFQAIADSEVGFLLAKKYLMDNVDSIS 847
            |..:..::.|:.:.|:|.||||...|. ..|||||:||...:||.:..|..||..::..|.:.|.
Zfish   822 KDKLRAAMACATQPWLLNRYLEYTLDA-NKIRKQDATSTIVSIASNVGGQSLAWDFVRANWEYIF 885

  Fly   848 KFYHPQSESMSELLPPLSEQIFTQRDYDEFMNFMASSKDQLKDI-----EQTISQSLETMLINVQ 907
            ..|...|.|.|.|:..::::..|:.:..:.|.|    |:..:.|     ...|.||:|....|::
Zfish   886 NQYGGGSFSFSNLINGVTKRFSTEFELKQLMQF----KEDNEHIGFGSGSLAIQQSIERTKANIK 946

  Fly   908 WKERN 912
            |.|:|
Zfish   947 WVEQN 951

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11951	NP_001350853.2	M1_APN-Q_like	35..490	CDD:341064	194/470 (41%)
		ERAP1_C	574..902	CDD:463368	104/332 (31%)
anpepb.1	NP_001082794.1	M1_APN-Q_like	88..544	CDD:341064	194/469 (41%)
		ERAP1_C	617..943	CDD:463368	104/334 (31%)