Protein Alignment CG11951 and CG2111

DIOPT Version :10

• Sequence 1: NP_001350853.2
• Gene: CG11951 / 43463
• FlyBaseID: FBgn0039656
• Length: 842
• Species: Drosophila melanogaster
• Sequence 2: NP_572644.1
• Gene: CG2111 / 31995
• FlyBaseID: FBgn0030223
• Length: 931
• Species: Drosophila melanogaster
• Alignment Length: 912
• Identity: 307/912 - (33%)
• Similarity: 495/912 - (54%)
• Gaps: 37/912 - (4%)

  Fly    26 RLPTALRPQSYDVRILTQLENPDDFHFNGTVKIQIEVLQNTHNITLHSKDLTIDDTE-ITLSQIG 89
            |||..|.|.||.|.|:|::..|.. .|.|||.|.:...::|..|.|::.||.|.... :|||...
  Fly    25 RLPKWLVPLSYRVDIVTRINQPYQ-PFGGTVVIDLRSERSTKRIVLNAHDLAIGKRRAVTLSDKN 88

  Fly    90 GEETTENCITSTAVNPTHDFYILNTCKELLAGQFYELSLPFSAKLQDQLAGYYRSSYVNTVANET 154
            |....   ::|..::.......::..:.|.....|.:.:.|::.|::...|:|.|:||:.....|
  Fly    89 GNSVP---VSSIQMDIKLSRLTVSLKRPLKVNVTYSMRVAFTSVLRNDNTGFYSSNYVDHNTTLT 150

  Fly   155 RWISVTQFEPAAARLAFPCFDEPGYKASFAITLGYHKKYTGLSNMPVNETRPHESIPDYVWTSFE 219
            :|::.|||||..||.||||||:|.::..|.|.|.:...|..||||||..|..|.|:.|||||.|.
  Fly   151 QWLAATQFEPNHAREAFPCFDDPIFRTPFKINLAHPYLYRALSNMPVQRTIRHASLKDYVWTQFV 215

  Fly   220 ESLPMSTYLVAYSLNDF------SHKPSTLPNGTLFRTWARPNAIDQCDYAAELGPKVLKYYEEL 278
            ||.||.|||||:.::.|      |.:.|..|    ..|||||:|:.|.::|..:...:|.:||:|
  Fly   216 ESHPMQTYLVAFMISKFDRPGFTSSERSDCP----ISTWARPDALSQTEFANMVVAPLLSFYEDL 276

  Fly   279 FGIKFPLPKVDQIAVPDFSAGAMENWGLVTFAESTLLYSPEYSSQEAKQETANIVAHELAHQWFG 343
            |...:...|:|.:|:|||:..:.|||||..|||.:|||..:.||.:.:|..|..||..:.:||||
  Fly   277 FNSTYRQKKIDLVALPDFTFKSKENWGLPAFAEESLLYDSQRSSIDDQQGVARAVAMMVVNQWFG 341

  Fly   344 NLVTMKWWTDLWLNEGFATYVASLCVEDIHPQWRTLQLESMSNLLTIFRKDSLESSHPISRPIEM 408
            |||::.||.::||...||.|::...|..:.|:|...:..::...|::...|:..::..::..:..
  Fly   342 NLVSVAWWHEIWLKNVFALYLSRFGVHSLRPEWDYQERHALQLYLSVLDYDAHVNTDLVTASVPD 406

  Fly   409 TSQISESFDEISYQKGSSVIRMMHLFLGEEAFRTGLKSYLEKYTYKNAEQDNLWESLTQAAHKTG 473
            .|.|..:::||..:|.:.:..|:|..:||||:.|.|:.||..|..:.|...:.|:.|.....:.|
  Fly   407 ESHIWAAYNEIGERKAAVLFEMLHRVMGEEAWLTALRRYLVVYANRTATSSDFWDLLQLQVDRNG 471

  Fly   474 SLPKDYNIKTIMDSWTLQTGYPVINVTRDYTSRTAKLSQERYLLNTDVSR--AHKGCWWVPLSYT 536
            .|.|..||..||..|..|.|||::.|||:|..|||.:||:|:.:......  |...|||||||||
  Fly   472 RLGKGLNITRIMKCWLGQPGYPLVTVTRNYDHRTAIVSQQRFFITPQFRNRWARNPCWWVPLSYT 536

  Fly   537 NQEEKDFNNTAPKEWMEC-TETGESVPKTI--HDLPG-PDQWVIFNNQLSAPYKVNYDAQNWKLL 597
            ....:.....:...|:.| |....|...|:  ..|.. |..|::||.|.:||::||||.:||:||
  Fly   537 CPSCQHSEIISFSRWLTCPTSKPSSKSNTVLLEKLEAEPTDWILFNVQHTAPFRVNYDLRNWQLL 601

  Fly   598 IETL-NSEDYHSIHVVNRAQLIDDVLYFAWTGEQDYEIALQVISYLERERELLPWKSAFDNLQFV 661
            .:|| :...:..||.||||||:||:...||:|:.:|::||.::.|||.|.|.:.|.:...:.:.:
  Fly   602 NKTLADPNKFRLIHRVNRAQLVDDLFSLAWSGDIEYDMALGILGYLEHEDEFVVWVATEISFERI 666

  Fly   662 SGILRQTPNFRFFKNFTRRLITPIYEHLNGINDTVASEEQQDKTILKAIVADWACSFEVSDCVTQ 726
            :.:.:..||:..||.:.|.|:...::.:...:.|.:|.....:.::..:    ||.:|:..||:.
  Fly   667 NNVAKSNPNYLIFKTYMRLLLERQFKRVISSDLTSSSGNMTHRPVIIRL----ACEYELPACVSL 727

  Fly   727 ALSFYRSWRSEANPDEVNPVPLGIRGVVYCTAIKHGCDEDWDFLWTRYQKANVATEKQIILDSLG 791
            |    |....:..|::...:.:..|..|.|||:|.|.:.|.|.:.:.|:::|.|.||:.:|.:|.
  Fly   728 A----RREFMKGTPEKGGWMTIRERETVVCTAVKFGTEGDRDMVESMYKRSNFAAEKESLLTALA 788

  Fly   792 CSQEVWVLQRYLERNFDGMGDIRKQDSTSVFQAIADSEVGFLLAKKYLMDNVDSISKFYHPQSES 856
            ||:.|:.|||.|...|:..| :|||::...|:|:..:.:|:.|||||:..|:.:|..:....::.
  Fly   789 CSRNVFALQRVLIWTFESSG-VRKQNARRTFKAVVSNSMGYRLAKKYVSVNMQNIRNYCSNSTDK 852

  Fly   857 MSELLPPLSEQIFTQRDYDEFMNFMASSKDQLKDI---EQTISQSLETMLINVQWKERNYERFTR 918
            :..|:.||.|.:.|.::...|..|.   |:.|:|:   |:.|...||....|:.|:...:....:
  Fly   853 VVNLMTPLIECLSTPKELLYFSKFF---KEILRDMNGSERLIKILLERGNDNIHWQRTKFRPMLQ 914

  Fly   919 AI 920
            ||
  Fly   915 AI 916

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11951	NP_001350853.2	M1_APN-Q_like	35..490	CDD:341064	161/461 (35%)
		ERAP1_C	574..902	CDD:463368	106/331 (32%)
CG2111	NP_572644.1	M1_APN-Q_like	33..487	CDD:341064	160/461 (35%)
		ERAP1_C	578..897	CDD:463368	105/330 (32%)