Protein Alignment CG11951 and R03G8.6

DIOPT Version :10

• Sequence 1: NP_001350853.2
• Gene: CG11951 / 43463
• FlyBaseID: FBgn0039656
• Length: 842
• Species: Drosophila melanogaster
• Sequence 2: NP_510175.1
• Gene: R03G8.6 / 181438
• WormBaseID: WBGene00011000
• Length: 747
• Species: Caenorhabditis elegans
• Alignment Length: 751
• Identity: 207/751 - (27%)
• Similarity: 331/751 - (44%)
• Gaps: 133/751 - (17%)

  Fly    25 FRLPTALRPQSYDVRILTQL------ENPDDFHFNGTVKIQIEVLQNTHNITLHSKDLTI----- 78
            :|||..:.|..||:.|.|.|      .:.:...|.|.|.|.:::.:.|..:.|||..|.|
 Worm    30 YRLPRHVSPSHYDIHIKTYLPGYGWKADENKITFEGNVNILLDIKETTDKLVLHSSSLNIISATF 94

  Fly    79 --DDTEITLSQIGGEETTENCITSTAVNPTHDFYILNTCKELLAGQFYELSLPFSAKLQDQLAGY 141
              |:..:::|. ...:|....:|         ||:.||.|           :..||.:|....|.
 Worm    95 QSDEQNVSISH-WNVQTESQFLT---------FYLNNTVK-----------VQSSAGIQINFQGK 138

  Fly   142 YRSSYVNTVA-NETRWIS------VTQFEPAAARLAFPCFDEPGYKASFAITLGYHKKYTGLSNM 199
            .|:..:...| |.||...      .||||...||...||||||.:||::.::|.:....|.|||.
 Worm   139 VRTDGLGLFATNSTREDGTVMTNFATQFETIFARNMIPCFDEPEFKATWNVSLEHPTGSTALSNG 203

  Fly   200 PVNETRPHESIPDYVWTSFEESLPMSTYLVAYSLNDFSHKPSTLPNGTLFRTWARPNAIDQCDYA 264
            ...|::.::   |:..|:::::|.||:|::|..:.|...|.:.|.||...|.:..|..||:.|:|
 Worm   204 IEVESKVND---DWKTTTYKKTLKMSSYILALFIGDIQFKETILNNGVRIRVYTDPVNIDRVDHA 265

  Fly   265 AELGPKVLKYYEELFGIKFPLPKVDQIAVPDFSAGAMENWGLVTFAESTLLYSPEYSSQEAKQET 329
            ..:...||:.:|..|||::|:.|:|.::|.:|..|||||||||.....:|:..|        .:.
 Worm   266 LNISRIVLEGFERQFGIRYPMEKLDFVSVQNFKFGAMENWGLVIHNAYSLIGDP--------MDV 322

  Fly   330 ANIVAHELAHQWFGNLVTMKWWTDLWLNEGFATYVASLCVEDIHPQWR--TLQLESMSNLLTIFR 392
            ..||.||:||||||||||||:|..:|||||||:|:.|..:..:.|.::  |..|....|......
 Worm   323 TEIVIHEIAHQWFGNLVTMKYWDHIWLNEGFASYMTSYGLTFLDPDYQRDTFYLNCQFNPQINDG 387

  Fly   393 KDSLESSHPISRPIEMTSQISESFDEISYQKGSSVIRMMHLFLGEEAFRTGLKSYLEKYTYKNAE 457
            ..||.....:|..:...:.:        |.||.|.:||:....|.|.|...:|.||||..|.|.:
 Worm   388 GVSLNFGKNLSSVMNNAATV--------YMKGCSFVRMLENIFGTEYFNEAIKFYLEKNQYDNVD 444

  Fly   458 QDNLWESLTQAAHKTGSLPKDYNIKTIMDSWTLQTGYPVINVTRD---YTSRTAKLSQERYLLNT 519
            .::|:|:...::....:..|.::|:.....||.|.|:|.|.|:.|   .|...:.|.:.:.:||.
 Worm   445 DNDLYEAFRTSSETLDTNGKPFDIEKFARCWTHQNGFPTIQVSNDNGIATLTQSHLYEPQLMLNE 509

  Fly   520 DVSRAHKGC---WWVPLSYTNQEEKDFNNTAPKEWMECTETG-ESVPKTIHDLPGPDQWVIFNNQ 580
                    |   |.:|:.|....|.    .....|:....|. |.|         .|..||.|..
 Worm   510 --------CDYKWDIPIWYQEPGEA----RVQMAWLNRNSTSLELV---------ADDSVIINAN 553

  Fly   581 LSAPYKVNYDAQNWKLLIE--TLNSEDYHSIHVVNRAQLIDDVLYFAWTGEQDYEIALQVISY-- 641
            ....|:|.|..:.::.:.|  .:|...| |::.:.|.  :.||..::..|...:..|. :|:|
 Worm   554 SIGYYEVLYSDKMYEKIAEQVAINVSRY-SVNSLRRT--LHDVFRYSRDGLTPFHNAF-IIAYVL 614

  Fly   642 LERERELLPWKSAF-----------------DNLQFVSGILRQTPNFRFFKN----------FTR 679
            :..|.|:|..:|..                 .:::.|.|::.|..||..|..          :.:
 Worm   615 VFGENEILRHESVLYLVDAVYNTNNKSIVNSKDIETVKGLVNQIENFELFPKCVQSQTFSSCYQK 679

  Fly   680 RLITPIYEHLNGINDTVASEEQQDKTILKAIVADWA 715
            |:  |...:|..|.....|:...|      ::..||
 Worm   680 RI--PQNINLRAIMQLKLSQNTMD------LIVAWA 707

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11951	NP_001350853.2	M1_APN-Q_like	35..490	CDD:341064	147/476 (31%)
		ERAP1_C	574..902	CDD:463368	35/173 (20%)
R03G8.6	NP_510175.1	M1_APN-Q_like	39..477	CDD:341064	147/477 (31%)
		ERAP1_C	548..>608	CDD:463368	14/62 (23%)