Protein Alignment CG11951 and mnp-1

DIOPT Version :10

• Sequence 1: NP_001350853.2
• Gene: CG11951 / 43463
• FlyBaseID: FBgn0039656
• Length: 842
• Species: Drosophila melanogaster
• Sequence 2: NP_497878.1
• Gene: mnp-1 / 175564
• WormBaseID: WBGene00007139
• Length: 781
• Species: Caenorhabditis elegans
• Alignment Length: 676
• Identity: 127/676 - (18%)
• Similarity: 247/676 - (36%)
• Gaps: 163/676 - (24%)

  Fly    28 PTALRPQSYDVRI-LTQLENP---DDFHFNGTVKIQIEVLQNTHNITLHSKDLTIDDTEITLSQI 88
            |:..:|..|.:.| :..:..|   .......:.|.|::.: :.|::.:|:.: ..|...:.....
 Worm   172 PSKFQPIHYVLNITIRDVRKPVLEGHMQLFASTKDQVQAI-SLHSVKIHNLE-NRDRIHVVNCNT 234

  Fly    89 GGEETTENCITSTAVNPTHDFYILNTCKELLAGQFYELSLPFSAKLQDQLAGYYRSS---YVNTV 150
            |  ||.  |:  :.|:...|...|...:.:.:|          ..|:..:.|:..:.   :|...
 Worm   235 G--ETI--CV--SRVHQIDDLIHLELAQSISSG----------VNLRVDIDGFISADSGPHVFKQ 283

  Fly   151 ANETRWISVTQ-----FEPAAARLAFPCFDEPGYKASFAITLGYHKKYTGLSNMPVNETRPHESI 210
            ....:| .|.|     |||.:||..||.||....|::|.:.|.:....:.::|..:|.......|
 Worm   284 IPTAKW-RVPQMIGSVFEPTSARHVFPSFDLHNQKSTFNLCLNHGPSMSAIANSLINPNVSTSGI 347

  Fly   211 PDYVWTSFEESLPMSTYLVAYSLNDFSHKPSTLPNGTLFRTWARPNA-IDQCDYAAELGPKVLKY 274
                 :.||:::|    |:|..|:..:.:.:   |...:.|.....| :.:.|....|..|..|.
 Worm   348 -----SCFEKTVP----LIAQQLSFVAFEKT---NPLFYNTTTMDGAYLPEIDMIFNLNAKNFKQ 400

  Fly   275 YEELF--------------GIKFPLPKVDQIAVPDFSAG--AMENWGLVTFAESTLLYSPEYSSQ 323
            ||.:.              |..:||.:::.:..| ..||  |:   |::|.....:.|....|:.
 Worm   401 YEWIHSEVSKVMALMSKWSGFSYPLTRLEIVVAP-VQAGHSAL---GVITLPAQAIAYQKHTSTH 461

  Fly   324 EAKQETANIVAHELAHQWFGNLVTMKWWTDLWLNEGFATYVASLCVEDIHPQWRTLQLE------ 382
            |.       :..|:..||...:||.:   .....:....||.....|::....:|.::|
 Worm   462 ET-------LIKEVIGQWMEGVVTTE---HTCFEKALIAYVEWKINEELQIVKKTRKMEVSKIRP 516

  Fly   383 ----SMSNLLTIFRKDSLESSHPIS-RPIEMTSQISESFDEISYQKGSSVIRMMHLFLGEEAFRT 442
                ..::.:.:.|:...:||:..| |.:|:...:.|::.:      .:||.|:.:...:.||.|
 Worm   517 RNLNETADSVRVLRQIKSQSSNLCSPRFVEVFYTLDETYGQ------ETVIGMIRVIFDKFAFST 575

  Fly   443 GLKSYLEKYTYKNAEQDNLWESLTQAAHKTGSLPKDYNIKTIMDSW---TLQTGYPVINVTRDYT 504
            ...|.              |.|..:.|  ||..|:   ...::..|   :.....||:...  .:
 Worm   576 ATISD--------------WASAAETA--TGGRPE---AGALIHQWYRPSSTISRPVLRAV--VS 619

  Fly   505 SRTAKLSQERYLLNTDVSRAHKGCWWVPLSYTNQEEKDFNNTAPKEWMECTETGESVPKTIHDLP 569
            |.:.:.:|    |..:.       |.|||        :.:.:|..:....:|..:::|....|
 Worm   620 SNSVEFNQ----LTEET-------WTVPL--------EISGSAGTQLAVISEKKQAIPFVSSD-- 663

  Fly   570 GPDQWVIFNNQLSAPYKVNYDAQNWKLLIETLN-----SEDYHSIHVVNRAQLIDDVLYFAWTGE 629
                :|:.:....:...|.|||..:..||....     |::...|.....|.|:.::|    ...
 Worm   664 ----YVVVDAGRKSHAFVVYDADTYLRLIRCFGDSRCPSKEIGGIFSDLGAALLANIL----PKP 720

  Fly   630 QDYEIALQVISYLERERELLPWKSAF 655
            ::.::|              .|||.|
 Worm   721 ENQDVA--------------KWKSVF 732

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11951	NP_001350853.2	M1_APN-Q_like	35..490	CDD:341064	95/497 (19%)
		ERAP1_C	574..902	CDD:463368	17/87 (20%)
mnp-1	NP_497878.1	PepN	172..687	CDD:440077	115/611 (19%)