Protein Alignment CG11951 and Y53F4B.20

DIOPT Version :10

• Sequence 1: NP_001350853.2
• Gene: CG11951 / 43463
• FlyBaseID: FBgn0039656
• Length: 842
• Species: Drosophila melanogaster
• Sequence 2: NP_497105.3
• Gene: Y53F4B.20 / 175160
• WormBaseID: WBGene00013166
• Length: 694
• Species: Caenorhabditis elegans
• Alignment Length: 669
• Identity: 143/669 - (21%)
• Similarity: 248/669 - (37%)
• Gaps: 164/669 - (24%)

  Fly    22 YDHFRLPTALRPQSYDVRI---LTQLENPDDFHFNGTVKIQIEVLQNTHNITLHSKDLTIDDTEI 83
            |...|||..|:|.|||:::   |:::.:||...|.|...:..|:.|
 Worm    27 YSDDRLPPILKPLSYDLQLQLPLSEVSDPDVPLFTGRCVMHFEINQ------------------- 72

  Fly    84 TLSQIGGEETTENCITSTAVNPTHDFYILNTCKEL-LAGQFYELSLPFSAKLQDQ---------- 137
               |||.|....:..||.......|..:|:..:.: |....:||.: |:.:|.|.
 Worm    73 ---QIGPESAFISDSTSNRARIKFDIIMLDHFENVSLVMNGHELEI-FNVQLTDDSMELSVDQPV 133

  Fly   138 ---------------LAG---YYRSSYVNTVANETRWISVTQFEPAAARLAFPCFDEPGYKASFA 184
                           |.|   |||.:..:.|.....:       |..|...||.:.....|.:|:
 Worm   134 LFPGRYTLTIHRYKGLIGSAIYYRDAGEHAVFGSNLF-------PNRAPAVFPSYLASTEKVTFS 191

  Fly   185 ITLGYHKKYTGLSNMPVNETRPHESIPDYVWTSFEESLPMSTYLVAYSL--NDFSHKPSTLPNGT 247
            ||: .|...|.......||..|.:...::..|:|..:..::..::.:.|  ::::|..||.....
 Worm   192 ITM-VHPVGTLALTSGSNEGAPRKIDENWQMTTFSTTPSITPSMLCFLLLPHEYTHIESTYTGVN 255

  Fly   248 L------FRTWARPNAIDQCDYAAELGPKVLKYYEELFGIKFPLPKVDQIAVPDFSAGAMENWGL 306
            :      ||...     :|..:......:||...:::|....|:||:|.|.:.:.|:.|.  :|.
 Worm   256 ISVHYNRFRVQK-----EQTKHLLHTATQVLALLKDIFSSLIPVPKIDIITMNEVSSTAC--FGS 313

  Fly   307 VTFAESTLLYSPEYSSQEAKQETANIVAHELAHQWFGNLVTMKWWTDLWLNEGFATYVASLCV-- 369
            :..:| ...:|.:|::|      ..::|..||.||.|....:...::|.|.|....::|...:
 Worm   314 IVVSE-VQFFSADYANQ------VKMLATWLAKQWIGGYAAISEGSELCLQEDLVAFIADKVIKR 371

  Fly   370 ------------------EDIHPQWRTLQLESMSNLLTIFRKDSLESSHPISRPIEMTSQISESF 416
                              |.|.....||:|:...|...||.|..|
 Worm   372 MTNDEFTRLGHLAKIYLSETIFTAGDTLKLDEHPNEFEIFEKCGL-------------------- 416

  Fly   417 DEISYQKGSSVIRMMHLFLGEEAFRTGLKSYLEKYTYKNAEQDNLWESLTQAAHKTGSLPKDYNI 481
                  ||.:::..:...:||::..:.:...:  |..|...    :.|.|.......::.:|..:
 Worm   417 ------KGVAMLESIESLIGEKSMISKINEMI--YNSKKGS----YSSRTLYGLLNSTVDEDIYV 469

  Fly   482 KTIMDSWTLQTGYPVINVTRDYTSRTAKLSQERYLLNTDVSRAHKGCW-----W-VPLSYTNQEE 540
            ..::..|....|.|.:||  |..:.:.|::|..  .|..|... .|.|     | :||.:|
 Worm   470 SQLLHYWHEHGGLPYMNV--DRLANSIKITQNG--SNMTVKNG-AGTWERMPLWPLPLKFT---- 525

  Fly   541 KDFNNTAPKEWMECTETGESVPKTIHDLPGPDQWVIFNNQLSAPYKVNYDAQNWKLLIETLNSED 605
             :|.  .|.:.|        |...||..|..|..:..|...:..|:||||...|: .|:|:.:|:
 Worm   526 -EFK--LPIQIM--------VSHGIHLSPIRDGLIFSNLGFTNYYRVNYDIDTWR-EIKTVLTEN 578

  Fly   606 YHSIHVVNRAQLIDDVLYF 624
            ..|..:..|.||:.|..||
 Worm   579 ATSYTLRERFQLVSDFCYF 597

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11951	NP_001350853.2	M1_APN-Q_like	35..490	CDD:341064	97/514 (19%)
		ERAP1_C	574..902	CDD:463368	17/51 (33%)
Y53F4B.20	NP_497105.3	GluZincin	39..>300	CDD:472708	59/296 (20%)
		ERAP1_C	552..>593	CDD:463368	14/41 (34%)