Protein Alignment CG11951 and LOC1275101

DIOPT Version :10

• Sequence 1: NP_001350853.2
• Gene: CG11951 / 43463
• FlyBaseID: FBgn0039656
• Length: 842
• Species: Drosophila melanogaster
• Sequence 2: XP_314331.5
• Gene: LOC1275101 / 1275101
• VectorBaseID: AGAMI1_000111
• Length: 915
• Species: Anopheles gambiae
• Alignment Length: 1000
• Identity: 289/1000 - (28%)
• Similarity: 456/1000 - (45%)
• Gaps: 173/1000 - (17%)

  Fly     3 CVFLILAAL-----------GLSFAGEGSTYDHFRLPTALRPQSYDVRILTQLENPDDFHFNGTV 56
            |..|:|:||           |:.   .|..:|.:|||....|..|.:|:.|.:.. :.|.:.|.|
Mosquito     9 CSALLLSALLAVTPSVVQARGIV---SGRAFDSYRLPNTTVPTHYTLRLDTDIHR-EIFDYTGNV 69

  Fly    57 KIQIEVLQNTHNITLHSKDLTIDDTEITLSQIGGEETTENCITSTAVNPTHDFYILNTCKELLAG 121
            :|:|.||:.|..|.|||     ..:|||..|:.........:.:...:...:|.::|....|...
Mosquito    70 QIRINVLEATDQIVLHS-----SRSEITHVQLRNGVGLSVPVKNFEFDEDKEFLVVNVGTTLQPN 129

  Fly   122 Q-FYELSLPFSAKL--QDQLAGYYRSSY--VNTVANETRWISVTQFEPAAARLAFPCFDEPGYKA 181
            . .|.|.:.|:..:  .|| ||:|||||  .|.|   .|::.:||||...||.:|||:||||.|.
Mosquito   130 TGTYTLEIDFTNSIARNDQ-AGFYRSSYDDENGV---RRYLGLTQFESVDARTSFPCYDEPGIKT 190

  Fly   182 SFAITLGYHKKYTGLSNMPVNETRPHESIPDYVWTSFEESLPMSTYLVAYSLNDFSHKPSTLPNG 246
            ::.|.:.....|...||.|:...:..|.  ....::|..:..|.|||||:.::||.::...|.:.
Mosquito   191 TYDILIVCGIDYHARSNAPLRGIQLLEG--GKKLSTFATTPRMQTYLVAWLVSDFKYEREVLTDP 253

  Fly   247 TL-FRTWARPNAIDQCDYAAELGPKVLKYYEELFGIKFPLPKVDQIAV--PDFSAGAMENWGLVT 308
            .| ..:|::|:::....|:.:...:.::..||.|...:.:.|:|.:|:  .|::|||||||||||
Mosquito   254 QLAIASWSKPSSVHLLSYSVDASKRFMRAMEEYFDQLYSMSKIDNVAIKDEDYAAGAMENWGLVT 318

  Fly   309 FAESTLLYSPEYSSQEAKQETANIVAHELAHQWFGNLVTMKWWTDLWLNEGFAT----YVASLCV 369
            :.||.:.|.|| ..::.:.....||.||..||:||||:..|||:.||||||||.    |:.::.
Mosquito   319 YKESAISYGPE-DGEQRQVGVVTIVGHEFTHQFFGNLLAPKWWSYLWLNEGFARLYQYYLGAIS- 381

  Fly   370 EDIHPQWRTLQLESMSNLLTIFRKDSLESSHPISRPIEMTSQISESFDEISYQKGSSVIRMMHLF 434
               ||:.:..:........|..|.|:..:..|::...|....||..||.|:|.|.:.|:|||:..
Mosquito   382 ---HPELQLRERFVTGPFQTALRADNSLTVRPMTYYTETRPSISRLFDSIAYDKSACVLRMMNYA 443

  Fly   435 LGEEAFRTGLKSYLEKYTYKN-AEQDNLWESLTQAAHKTGSLPKDYNIKTIMDSWTLQTGYPVIN 498
            |||..|:.||:.||::...:. .|:.||::||.|||.:...||...:|..|..||:.|.|.|::.
Mosquito   444 LGERTFQKGLRYYLQQNKERGVVEESNLFDSLEQAAKEDAVLPISLSIHEIFGSWSHQPGVPLVK 508

  Fly   499 VTRDYTSRTAKLSQERYLLNTDVSRAHKGCWWVPLSYTNQEEKDFNNTAPKEWM-----ECTETG 558
            |.||  ......:||||:.||......:..||:|:|::......|.. .|..||     |...|.
Mosquito   509 VRRD--GNEYLFTQERYIANTPPEEPFENSWWIPISFSTPSNNAFEK-LPAFWMPPNVSEVAYTI 570

  Fly   559 ESVPKTIHDLPGPDQWVIFNNQLSAPYKVNYDAQNWKLLIETLNSEDYHSIHVVNRAQLIDDVLY 623
            |:|         .|:.|.||...:..|:|.|:....:.|||.:| :|:.......||:||||.|.
Mosquito   571 ETV---------QDEVVSFNPHSTGYYRVEYEESMLRELIERIN-KDHTGFEPATRARLIDDTLN 625

  Fly   624 FAWTGEQDYEIALQVISYLERERELLPWKSAFDNLQFVSGILRQTPNF-RFFKNFTRRLITPIYE 687
            .|.:...:|::.||:::||:||.:.:||..|::||:.:..:||..... :..:.|..::.:|:.|
Mosquito   626 IAQSRGGNYDVVLQLLNYLQRETDYVPWAVAYENLRHMQSMLRTNEAVSQLLERFIEKIASPLLE 690

  Fly   688 -----HLNGINDTVASEEQQDKTILKAIVADWACSFEVSDCVTQALSFYRSWRSEANPDEVNPVP 747
                 |..|.:.:|..        |:.|..|.|||...| |...|.|..||..|:
Mosquito   691 RYGVDHRTGESASVGE--------LRTIAIDLACSGSQS-CKDDAQSAVRSLASK---------- 736

  Fly   748 LGIRGVVYCTAIKHGCDEDWDFLWTRYQKANV---------------------ATEKQIILDSLG 791
                        ||...||...|....|::|.                     .:.||.:|.||.
Mosquito   737 ------------KHYTMEDNALLCHGLQQSNAEQRKSLQAQFSQVLSDKNLDNPSAKQFLLQSLS 789

  Fly   792 CSQEVWVLQRYLERNFDGMGDIRK-QDSTSVFQAIADSEVGFLLAKKYLMDNVDSISKFYHPQSE 855
            |..                ||:.| |.......|:::|:....|.:..:..||        |.:|
Mosquito   790 CLG----------------GDMTKVQSFAKYLLALSESDRTKALHRLLVELNV--------PLAE 830

  Fly   856 SMSELLPPLSEQ-------------IFTQRDY------DEFMNFMASSKDQ--LKDIEQTISQSL 899
            .:..|...||::             ||....|      .:.::.:|||.|.  ..:|||.::
Mosquito   831 IVQSLQSELSQRRSNSVYYKHGPKLIFEIARYVTDPADVQLLSSVASSYDSWVASEIEQQVN--- 892

  Fly   900 ETMLINVQWKERNYERFTRAISKHF 924
                .|:.|.|:|.|....|::::|
Mosquito   893 ----ANLNWVEQNVEPLKNALARYF 913

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11951	NP_001350853.2	M1_APN-Q_like	35..490	CDD:341064	156/467 (33%)
		ERAP1_C	574..902	CDD:463368	89/376 (24%)
LOC1275101	XP_314331.5	None