Protein Alignment CG11951 and LOC1273751

DIOPT Version :10

• Sequence 1: NP_001350853.2
• Gene: CG11951 / 43463
• FlyBaseID: FBgn0039656
• Length: 842
• Species: Drosophila melanogaster
• Sequence 2: XP_003436384.2
• Gene: LOC1273751 / 1273751
• VectorBaseID: AGAMI1_009321
• Length: 1054
• Species: Anopheles gambiae
• Alignment Length: 904
• Identity: 295/904 - (32%)
• Similarity: 467/904 - (51%)
• Gaps: 51/904 - (5%)

  Fly    25 FRLPTALRPQSYDVRILTQLENPDDFHFNGTVKIQIEVLQNTHNITLHSKDLTIDDTEITLSQIG 89
            ||||..:||..|::.:...|:...   |:|.|.|::.|.::|:.|.||||.|:|.:|.:.....|
Mosquito   171 FRLPRHIRPVHYELWLQPDLQRET---FSGRVGIELNVSESTNYIVLHSKKLSITETVLRTLGTG 232

  Fly    90 GEETTENCITSTAVNPTHDFYILNTCKELLAGQFYELSLPFSAKLQDQLAGYYRSSYVNTVANET 154
            .||.|   |......|.|:::::.|..|:.||. |.||:.|:..|.|::.|:|.|.|::...|.|
Mosquito   233 PEEVT---IARAYELPEHEYWVIETQGEIGAGA-YRLSVQFNGSLADRIIGFYSSKYLDKTTNRT 293

  Fly   155 RWISVTQFEPAAARLAFPCFDEPGYKASFAITLGYHKK---YTGLSNMPVNETRPHESIPDYVWT 216
            |.|:.::|||..||.||||||||..||.:.|.: .|..   |..||||.|.||...:.......|
Mosquito   294 RTIATSKFEPTFARQAFPCFDEPHLKAEYTIHM-VHPSGDGYAALSNMNVKETVADKPSAGLSTT 357

  Fly   217 SFEESLPMSTYLVAYSLNDFSHKPSTL--PNGTLF--RTWARPNAIDQCDYAAELGPKVLKYYEE 277
            :||.|:.||||||.:.::||.|:...:  .:|:.|  |.:|.|...:...||......:::||.:
Mosquito   358 TFERSVSMSTYLVVFIVSDFLHQEVLIVPEHGSSFPLRVYATPFQQENTAYALATARTIIQYYVK 422

  Fly   278 LFGIKFPLPKVDQIAVPDFSAGAMENWGLVTFAESTLLYSPEYSSQEAKQETANIVAHELAHQWF 342
            .|||.:||||:|..|:|||.:||||.|||||:.|:::||:...||...||..|.::||||||.||
Mosquito   423 YFGIAYPLPKLDMAAIPDFVSGAMETWGLVTYRETSILYNSVTSSTANKQRVAGVIAHELAHMWF 487

  Fly   343 GNLVTMKWWTDLWLNEGFATYVASLCVEDIHPQWRTLQLESMSNLLTIFRKDSLESSHPISRPIE 407
            |||||||||.:||||||||:|:....::..||.|...:...:.:|..:...|:...||||...:|
Mosquito   488 GNLVTMKWWNELWLNEGFASYIEYKGMDAAHPDWGIEEQFIIDDLHGVLNLDATLGSHPIVMSVE 552

  Fly   408 MTSQISESFDEISYQKGSSVIRMMHLFLGEEAFRTGLKSYLEKYTYKNAEQDNLWESLTQAAHKT 472
            ..:||:|.||.|:|.||:|||||:..|:....|:.|:|.||||..|.|:..::|...|.:
Mosquito   553 NPNQITEIFDTITYSKGASVIRMLEDFVTPPVFQQGVKRYLEKLAYANSVSEDLMRELDE----- 612

  Fly   473 GSLPKDYNIKTIMDSWTLQTGYPVINVTRDYTSRTAKLSQERYLLNTDVSRAHKG----CWWVPL 533
              |..|.::..:||::|.|.|.||:.|..:.....  |.|:|:|.:.|.:...:.    .|::|:
Mosquito   613 --LVPDVSVTGVMDTFTRQKGLPVVTVAENALQYV--LRQQRFLADQDANETEESPYGYRWYIPI 673

  Fly   534 SYTNQEEKDFNNTAPKE-WMECTETGESVPKTIHDLPGPDQWVIFNNQLSAPYKVNYDAQNWKLL 597
            :|....: |....||:. |.   ....|.|:.:.|.|....|:..|.:....|:|||....|:..
Mosquito   674 TYLASTD-DPATAAPRRIWF---PNDASRPELVIDKPAGSSWIKLNYRQIGYYRVNYPIAMWQQF 734

  Fly   598 IETLNSEDYHSIHVVNRAQLIDDVLYFAWTGEQDYEIALQVISYLERERELLPWKSAFDNLQFVS 662
            .|.|..| .::..:.:|..|::|....|......|..||::..||..|.|.:||.:....|:.:.
Mosquito   735 GEALRKE-VNTFTIGDRTGLLNDAFALADASLLAYNHALELTRYLSGETEYVPWSAIASKLKNIR 798

  Fly   663 GILRQTPNFRFFKNFTRRLITPIYEHLNGINDTVASEEQQDKTILKAIVADWACSFEVSDCVTQA 727
            .:|.   |::.:.:.|....|.:...:..:...|.:|......:|:..:.|.||||....|:.:|
Mosquito   799 NLLY---NYQSYDDITTYTQTLVDAAVKSVGWDVPAEGGHMTNLLRTTILDLACSFGHPACLEEA 860

  Fly   728 LSFYRSWRSEA---NPDEVNPVPLGIRGVVYCTAIKHGCD-EDWDFLWTRYQKANVATEKQIILD 788
            ...:|.|.::.   :||        :|.|||...|:.|.. .|||.:..|:::.|.|.||..::.
Mosquito   861 SKQFRGWLNDGAVIHPD--------LRSVVYTYGIQSGVTVADWDKVLERFRQENDANEKTKLMV 917

  Fly   789 SLGCSQEVWVLQRYLERNFDGMGDIRKQDSTSVFQAIADSEVGFLLAKKYLMDNVDSISKFYHPQ 853
            :|....:...::|:|:.::| ...:|.||..|..|.||.:..|...|.:::.:|...:...:...
Mosquito   918 ALASYPDQRTMRRFLDLSWD-TALVRTQDQLSCIQYIAANRAGEQAAWEHVRENWPRLVARFGIG 981

  Fly   854 SESMSELLPPLSEQIFTQRDYDEFMNFMASSKDQLKDIEQTISQSLETMLINVQWKERN 912
            ..::..::|.::.:..||....|..:|.|...:........ .|:||.:..|:.|.|||
Mosquito   982 ERNLGRMIPSVTGRFTTQARLTELEDFFARYPESGAGATAR-RQALENIQNNISWLERN 1039

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11951	NP_001350853.2	M1_APN-Q_like	35..490	CDD:341064	183/461 (40%)
		ERAP1_C	574..902	CDD:463368	79/331 (24%)
LOC1273751	XP_003436384.2	None