Protein Alignment CG11951 and rnpepl1

DIOPT Version :10

• Sequence 1: NP_001350853.2
• Gene: CG11951 / 43463
• FlyBaseID: FBgn0039656
• Length: 842
• Species: Drosophila melanogaster
• Sequence 2: NP_001335117.1
• Gene: rnpepl1 / 100535895
• ZFINID: ZDB-GENE-030131-5522
• Length: 692
• Species: Danio rerio
• Alignment Length: 745
• Identity: 171/745 - (22%)
• Similarity: 273/745 - (36%)
• Gaps: 192/745 - (25%)

  Fly     3 CVFLILAALGLSFAGEGSTYDHFRLPTALRPQSYDVRILTQLENPDDFHFNGTVK---------- 57
            |...:|...|.|..| |.:..|.||.......::....|.....  |.|.|..||
Zfish    11 CCRKVLTVPGKSCEG-GRSLAHCRLVDIASASNFHCFKLRHFHL--DLHLNFAVKRITGWQVLEL 72

  Fly    58 ------IQIEVLQNTHNITLHSKDLTIDDTEITLSQIGGEETTENCITST-AVNPTHDFYILNTC 115
                  :|..:|....::.:||.|..:.         |.....:..::.| .|.|..|:
Zfish    73 TPVQPGVQSLILDTHPSLLIHSVDCKVP---------GASGAPDVFLSLTYRVEPFTDY------ 122

  Fly   116 KELLAGQFYELSLPFSAKLQDQLAGYYRSSYVNT------------VANETRWISVTQFEPAAAR 168
                 |....::|| :|.::...|......|..|            ...:||.:..||......|
Zfish   123 -----GSSLNITLP-AAVIRPHRAFRVTVRYTTTDGPAIWWLDAELTCGQTRPLVFTQGHSVCNR 181

  Fly   169 LAFPCFDEPGYKASFAITLGYHKKYTGLSNMPVNETRPHESIPDYVWTSFEESLPMSTYLVAYSL 233
            ..|||||.|..|::::.|:...:..|.|    ::.:|...|..|.|: .|....|:..||||...
Zfish   182 SFFPCFDTPAVKSTYSATVRVPEGVTVL----MSASRSAYSKQDRVF-QFSMEYPVPAYLVALVA 241

  Fly   234 NDFSHKPSTLPNGTLFRTWARPNAIDQCDYAAELGPKV---LKYYEELFGIKFPLPKVDQIAV-P 294
            .|..|...    |...|.||.| .|..| ..::||..|   |...|.||| .:...:.|.:.: |
Zfish   242 GDLQHADI----GPRSRVWAEP-CILTC-AVSKLGGSVERWLNVAEGLFG-PYVWGRYDLVFLPP 299

  Fly   295 DFSAGAMENWGLVTFAESTLLYSPEYSSQEAKQETANIVAHELAHQWFGNLVTMKWWTDLWLNEG 359
            .|...|||| ..:||..|::|.|.|:...:        |.||:||.||||.||...|.::||:||
Zfish   300 SFPIVAMEN-PCLTFIISSILESQEFLLID--------VIHEIAHGWFGNAVTNATWEEMWLSEG 355

  Fly   360 FATYVASLCVEDIHPQWRTLQLESMSNLLTIFRKDSLE-------SSHPISR---PIEMTSQISE 414
            .|||.......:.:.       |:.:.|.|:||.|:|.       .::|:|:   ..|.....|.
Zfish   356 LATYAQRRITTEAYG-------EAFTCLETVFRLDALHRQMRLLGDNNPVSKLQAKFEPGVNPSS 413

  Fly   415 SFDEISYQKGSSVIRMMHLFLGE-EAFRTGLKSYLEKYTYKNAEQDNLWESLTQAAHKTGSLPKD 478
            ..:..:|:||...:..:....|: :.|.:.|::|:||:.:.:....:|.:..      .|..|:
Zfish   414 LMNLFTYEKGFCFVSYLSQLCGDIKRFDSFLRAYIEKFRFSSVIAQDLLDFF------LGFFPE- 471

  Fly   479 YNIKTIMDSWTLQTGYPVINVTRDYTSRTAKLSQERYLLNTDVSRAHKGCWWVPLSYTNQEEKDF 543
                       |:.|         ..::...|..||:|         .|| ..||.     |.|.
Zfish   472 -----------LKEG---------CVAQREGLEFERWL---------NGC-GPPLC-----EPDL 501

  Fly   544 NN----TAPKEWMECTETGESVPKTIHDLPGPDQWVIFNNQLSAPYKVNYDAQNWKLLIETLNSE 604
            :.    |.|.:.: |...|..         .||..||          ..:|..:|......|..:
Zfish   502 SAGRTLTGPVQHL-CDLWGND---------APDTQVI----------STFDLSSWSTFQTVLFLD 546

  Fly   605 DYHSIHVVNRAQLIDDVL------YFAWTGEQDYEIALQVISYLERERELLPWKSAFDNLQFVSG 663
                 .:::|:.|..:|:      |.|...:.:.|:.::.:..:.|       .|.:.:|
Zfish   547 -----RLLDRSPLSQEVMSLLSSCYAALLDDMNAEVQIRWLQIVVR-------NSFYPDL----- 594

  Fly   664 ILRQTPNFRFF--KNFTRRLITPIYEHLNG 691
                 |..|.|  |:.:|....|:||.|.|
Zfish   595 -----PRVRSFLHKHTSRMYTVPLYEDLCG 619

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11951	NP_001350853.2	M1_APN-Q_like	35..490	CDD:341064	120/498 (24%)
		ERAP1_C	574..902	CDD:463368	24/126 (19%)
rnpepl1	NP_001335117.1	M1_LTA4H	36..490	CDD:341062	126/540 (23%)
		Leuk-A4-hydro_C	536..649	CDD:462686	21/106 (20%)