Protein Alignment CG11951 and LOC100004744

DIOPT Version :10

• Sequence 1: NP_001350853.2
• Gene: CG11951 / 43463
• FlyBaseID: FBgn0039656
• Length: 842
• Species: Drosophila melanogaster
• Sequence 2: XP_001920418.2
• Gene: LOC100004744 / 100004744
• -ID: -
• Length: 935
• Species: Danio rerio
• Alignment Length: 961
• Identity: 325/961 - (33%)
• Similarity: 503/961 - (52%)
• Gaps: 78/961 - (8%)

  Fly     1 MKCVFLILAALGLSFAGEGS---------------TYDH------FRLPTALRPQSYDVRILTQL 44
            ||.:......||.:|.|..|               |..|      :|||..|.|..|::.:..:|
Zfish     1 MKRIHFSAMCLGCTFLGMASLATIVGLWTVQLLPTTESHVEPWKEYRLPDTLFPHYYNITLWPRL 65

  Fly    45 ENPDD---FHFNGTVKIQIEVLQNTHNITLHSKDLTIDDTEITLSQIGGEETTE-NCITSTAVNP 105
            : |||   :.|.|...:..:.|:.|..|.:|...|.:...:..|:::....|:| ..:..|.:..
Zfish    66 Q-PDDHGLYVFTGNSSVVFKCLRETDIIIIHCNKLNLTSEDGYLAKLSAFSTSEVPSVKKTWIEE 129

  Fly   106 THDFYILNTCKELLAGQFYELSLPFSAKLQDQLAGYYRSSYVNTVANETRWISVTQFEPAAARLA 170
            ...:.:|....:|.||:.|.|...|..:|.|.|||.|||.|...  .|.:.::.:|..|..||..
Zfish   130 MTQYLVLQLNGKLKAGELYVLYTEFVGELADDLAGLYRSEYDED--GEKKIVATSQMHPTHARKT 192

  Fly   171 FPCFDEPGYKASFAITLGYHKKYTGLSN-MPVNETRPHESIPD---YVWTSFEESLPMSTYLVAY 231
            |||||||..||.|.|||.:.:....||| |.:...   ::|.|   ...|:||.:..||:||:|.
Zfish   193 FPCFDEPAMKAVFHITLIHDRGTVALSNGMEIENV---DTIVDGQPVTVTTFEPTKIMSSYLLAL 254

  Fly   232 SLNDFSHKPSTLPNGTLFRTWARPNAID--QCDYAAELGPKVLKYYEELFGIKFPLPKVDQIAVP 294
            .::|:::..|.  :|||.|.|||..||:  ..|||..:...:||::|..:.:.:||.|.||||:|
Zfish   255 VVSDYTNVTSA--DGTLIRIWARKKAIEDGHGDYALNITGPILKFFENYYNVPYPLSKSDQIALP 317

  Fly   295 DFSAGAMENWGLVTFAESTLLYSPEYSSQEAKQETANIVAHELAHQWFGNLVTMKWWTDLWLNEG 359
            ||..|||||||||.:.||.|||.|..||...|:.||.|:||||||.|||||||:|||.::|||||
Zfish   318 DFYFGAMENWGLVMYRESNLLYDPTVSSNANKERTATIIAHELAHMWFGNLVTLKWWNEVWLNEG 382

  Fly   360 FATYVASLCVEDIHPQWRTLQLESMSNLLTIFRKDSLESSHPIS---RPIEMTSQISESFDEISY 421
            ||:||:.|..:...|.|....|..:.::..:|..|:|.||||:|   ..|....||.|.||.:||
Zfish   383 FASYVSYLGADFAEPSWNVKDLIILKDVHRVFAVDALASSHPLSSKEEDIIKPEQIIEQFDTVSY 447

  Fly   422 QKGSSVIRMMHLFLGEEAFRTGLKSYLEKYTYKNAEQDNLWESLTQAAHKTGS-LPKDYNIKTIM 485
            .||:||:||:..||.|..|..||.:||..:..:|...::||:.|..|.:|||: ||  .::|.||
Zfish   448 SKGASVLRMLSDFLTEPVFVQGLNTYLTMFADQNTVGEDLWDHLQTAVNKTGTVLP--LSVKVIM 510

  Fly   486 DSWTLQTGYPVINVTRDYTSRTAKLSQERYLLNTDVSRAHKGC----WWVPLSYTNQEEKDFNNT 546
            |.|.||.|:||:.|    .:.|.::||..:||:.:.|......    |.||:::...:     ..
Zfish   511 DRWVLQMGFPVVTV----NTTTGQVSQMHFLLDPESSLQRTSPFNYEWIVPINWMKSK-----MV 566

  Fly   547 APKEW-MECTETGESVPKTIHDLPGPDQWVIFNNQLSAPYKVNYDAQNWKLLIETLNSEDYHSIH 610
            ..:.| :|.|.....:..|      ..:||:.|..::..|:||||..||:.|:..| :|::..|.
Zfish   567 QSRFWLLERTAVYNDMKTT------GSEWVLLNLNITGYYRVNYDIGNWERLLNQL-AENHKVIS 624

  Fly   611 VVNRAQLIDDVLYFAWTGEQDYEIALQVISYLERERELLPWKSAFDNLQFVSGILRQTPNFRFFK 675
            |:||||::||....|........:||:..:||..|||.:||:||.:||.:...:..||..:|..:
Zfish   625 VINRAQIVDDAFNLARAKIIPVTLALKTTTYLSEEREYMPWQSALNNLDYFYLMFTQTEVYRLLQ 689

  Fly   676 NFTRRLITPIYEHLNGIND---TVASEEQQDKTILKAIVADWACSFEVSDCVTQALSFYRSWRSE 737
            ::|::.:||::::...|.:   .|.|........:.||  .:|||..|.:|.....|:|:.|..:
Zfish   690 SYTKKQVTPLFDYFKTITEDWSDVPSGHTDQYNQVNAI--RFACSTGVDECQNLTSSWYKQWMDQ 752

  Fly   738 ANPDEVNPVPLGIRGVVYCTAIKHGCDEDWDFLWTRYQKANVATEKQIILDSLGCSQEVWVLQRY 802
            .|.   ||:...:|..|||:||..|..|:|||.||.::.|.:..:|  ::.||.|::...:|:||
Zfish   753 PNH---NPIHPNLRSTVYCSAIATGGAEEWDFGWTMFKNAAIEADK--LMSSLACAKNQTLLKRY 812

  Fly   803 LERNFDGMGDIRKQDSTSVFQAIADSEVGFLLAKKYLMDNVDSISKFYHPQSESMSELLPPLSEQ 867
            |....| ...|||||:|||...||.:..|..||.:::.:..:.:...|...|.:.:.|:..:::.
Zfish   813 LGYTLD-PSMIRKQDATSVIVYIASNPDGQKLAWEFVRNKWEYMFTEYGVGSFNFASLISGITKT 876

  Fly   868 IFTQRDYDEFMNFMA-SSKDQLKDIEQTISQSLETMLINVQWKERNYERFT 917
            ..|:.:.::.:.|.: :|:.........:.|::|....|::|...|.|..|
Zfish   877 FSTEAELEQLLKFKSDNSEIGFGSATAALEQAIEKTKANIKWVAENQEDIT 927

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11951	NP_001350853.2	M1_APN-Q_like	35..490	CDD:341064	186/468 (40%)
		ERAP1_C	574..902	CDD:463368	101/331 (31%)
LOC100004744	XP_001920418.2	M1_APN-Q_like	57..515	CDD:341064	186/467 (40%)
		ERAP1_C	589..914	CDD:463368	101/333 (30%)