Protein Alignment Usp1 and Usp5

DIOPT Version :10

• Sequence 1: NP_651687.3
• Gene: Usp1 / 43462
• FlyBaseID: FBgn0028476
• Length: 1078
• Species: Drosophila melanogaster
• Sequence 2: NP_647773.1
• Gene: Usp5 / 38375
• FlyBaseID: FBgn0035402
• Length: 827
• Species: Drosophila melanogaster
• Alignment Length: 821
• Identity: 140/821 - (17%)
• Similarity: 235/821 - (28%)
• Gaps: 335/821 - (40%)

  Fly   199 ELEIQSPETAAAIAAAQAELNAAGKSGAAG-----ARSSRKRTNTMSLYD--RRFQTTTEE---- 252
            ||.::..::..||.||.:.:....|:...|     .|.:.|..:.:...|  :|...:..:
  Fly   143 ELPMRVTQSVEAILAADSAIAKLEKATLMGTWDGEVRQASKYADNLQQLDNGKRIPPSGWQCEKC 207

  Fly   253 ------------------RRVANGYGGN--------------AAR--SVTGSSSNEIESQEPQSH 283
                              |:..:|.|||              |.:  ::|....:::.|. |:..
  Fly   208 DLTNNLWLNLTDGSIMCGRKFFDGSGGNDHAVEHYRVTGFPLAVKLGTITADGKSDVFSY-PEDE 271

  Fly   284 QYYGP-------NGGSNAA--------------------GAGAGLNGSAAALN--HAPSMGTLCN 319
            ....|       :.|.|.|                    |....|..|.:.|.  ..|....:.|
  Fly   272 MVLDPHLERHLSHFGINMAAMKKSEKSMVELELDINQRIGEWTALTESESELQPVAGPGYTGMRN 336

  Fly   320 IGNSCYLNSVVYTLRFAPHFLHNLHHLIQDLNVVQQTIVRQQTARSASLGKNVSAAQLEHARSWS 384
            :|||||:|||:..|...|.|              ||..|
  Fly   337 LGNSCYINSVMQVLFVIPDF--------------QQRFV-------------------------- 361

  Fly   385 SKDLATSTDQY-------SGQNGGVNSGNGGSGSSKSTHQSVTEKLHE----------LYNNLHG 432
                .|..::|       ...:..:.....|:|.....:.|:.|...:          ::.|:.|
  Fly   362 ----GTGAERYFKEFPSDPANDFNIQMAKLGTGLQSGKYSSIAENTLDTDHSTGISPAMFKNIVG 422

  Fly   433 NEMADSTEPYHADTLLHAIQDVNATFEGNQQQDAHEFLMCVLNCI--RETNQSLIKAIGECPEVI 495
            ..        |.|            |...|||||::|.:.:|..:  ...||:
  Fly   423 KN--------HPD------------FSTKQQQDANDFYLHLLTLLDRNSRNQT------------ 455

  Fly   496 ANGYIANPDEVDTGEGQDRTDSTASQNLNAGNGSLATSQTTTTKTSFFSR------KSKRKDEV- 553
                  ||.:......:||.:..||..:.           ..|:..:..|      |:...|||
  Fly   456 ------NPADALKFLLEDRVECLASHKVK-----------YNTREEYSFRLPVPLDKATNLDEVR 503

  Fly   554 ------KPSKST----------RVQSPLKE--------------NSPTAGGITGAG--TAHATAN 586
                  |.::.|          |.:.||:.              .|...|..|.|.  |..||..
  Fly   504 EFQERKKAARETGQRLPDRDIVRHKVPLQACLERFFGPELIEQFYSTAIGSKTNARKITRLATMP 568

  Fly   587 SLFYLN-----------------TVDLSGASSTSGSASTSASGVVSTSAALPTP-PQATKYSSDD 633
            ....::                 :||:......|.  ..||.|:.....|||.| .:..|::.|:
  Fly   569 DCLMIHVGKFTLGDDWVPKKLDVSVDMPDELDLSN--WRSAGGLQPGEEALPEPATEEVKFAFDE 631

  Fly   634 EMNSATVLKDKMRLEERIRELNLNF---------FSSDFEGIVVLTTKCLSCETITRQKQGMLDI 689
            .:.|..              |.:.|         :.:...|:...:...:  |.|..:     ||
  Fly   632 AVMSEL--------------LTMGFPPEACKRACYHTKNSGLEAASNWLM--EHIADE-----DI 675

  Fly   690 SVPVPISGYDNADLQDKPSTYIQNSCITKEYFRGENKYSCNQCTGYTEAIRSISYEVLPRLLVIQ 754
            |.|..:           |:..| ..|...::.......:.....|:.|           |..|..
  Fly   676 SEPFVV-----------PNNSI-GDCAANQFVANPESLAMLMSMGFDE-----------RQAVAA 717

  Fly   755 LNRFSGGMEKVSTYV-------------PTTFTLPCFCA-----TCCELGEGNKLHVYKLYSVIT 801
            |....|.:|:.:.::             |...:.....:     |....|.|.    |:|.:.|:
  Fly   718 LKATDGNVERATDWIFSHADSIGVEDAAPAANSSAAAASSTPNKTNYRDGRGK----YRLVAFIS 778

  Fly   802 HVGATLTVGHYIAYTCFLDLASDYV-----------NCPKD 831
            |:|.:..||||:   |.:....::|           |.|||
  Fly   779 HMGTSAQVGHYV---CHIRKKGEWVIFNDSKVAKSQNPPKD 816

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp1	NP_651687.3	Peptidase_C19	308..819	CDD:470612	107/615 (17%)
Usp5	NP_647773.1	zf-UBP_var	11..77	CDD:407678
		zf-UBP	204..278	CDD:460464	10/74 (14%)
		Peptidase_C19B	333..823	CDD:239123	110/630 (17%)
		UBA1_UBP5_like	631..674	CDD:270480	6/63 (10%)
		UBA2_UBP5	696..737	CDD:270569	7/51 (14%)