Protein Alignment Usp1 and Usp35

DIOPT Version :10

• Sequence 1: NP_651687.3
• Gene: Usp1 / 43462
• FlyBaseID: FBgn0028476
• Length: 1078
• Species: Drosophila melanogaster
• Sequence 2: XP_006507886.1
• Gene: Usp35 / 244144
• MGIID: 2685339
• Length: 1072
• Species: Mus musculus
• Alignment Length: 685
• Identity: 131/685 - (19%)
• Similarity: 214/685 - (31%)
• Gaps: 194/685 - (28%)

  Fly   279 EPQSHQYYGPNGGSNAAGAGAGLNGSAAALNHAPSMGTLCNIGNSCYLNSVVYTLRFAPHFLHNL 343
            |.:..|..|.:..::.....||......|.:....:| |.|:||:||:|||:..|..|..|.|.:
Mouse   469 EDRIKQLLGQDAWTSQKSELAGFYPRLMAKSDTGKIG-LINLGNTCYVNSVLQALFMASDFRHCV 532

  Fly   344 HHLIQDLNVVQQTIVRQQTARSASLGKNVSAAQLEHARSWSSKDLATSTDQYSGQNGGVNSGNGG 408
            ..|.:  |..|..:.:.|..          .|.|||:                 |...::..|..
Mouse   533 LRLTE--NNSQPLMTKLQWL----------FAFLEHS-----------------QRPAISPENFL 568

  Fly   409 SGS-----SKSTHQSVTEKLHELYNNLHGNE---------MADSTEPYHADTLLHAIQDVNATFE 459
            |.|     |..|.|..:|.|..|.:.||..|         :..|:.|...:.|    ...|||..
Mouse   569 SASWTPWFSPGTQQDCSEYLKYLLDRLHEEEKTGMRICQKLKQSSLPSPQEEL----PSSNATSV 629

  Fly   460 GNQQQDAHEFLMCVLNCIRETNQSLIKAIGECPEVIANGYIANPDEVDTGEGQDRTDSTASQNLN 524
            ...........:|.|:|:..:::.         |...:..:|.|            ....|::..
Mouse   630 EKMFGGKIVTRICCLHCLNVSSRE---------EAFTDLSLAFP------------PPERSRHRR 673

  Fly   525 AGNGSLATSQTTTTKTSFFSRKSKRKDEVKPSKSTRVQSPLKENSPTAGGITGAGTAHATANSLF 589
            .|:..|.|......:.:...|        .|....:.:..:..::|.. |:...|
Mouse   674 LGSVMLPTEDVRVQELTLAPR--------APGAQRQRKRCITGDAPRT-GLDSEG---------- 719

  Fly   590 YLNTVDLSGASSTSGSASTSASGVVSTSAALPTPPQATKYS--SDDEMNSATVLKDKMRLEERIR 652
                ||..|....||.......             ||.|..  ::|.....|..::|...||:.:
Mouse   720 ----VDTIGTGGRSGQEKVERE-------------QAGKEKEVAEDREEEGTREEEKEEGEEKDK 767

  Fly   653 ELNLNFFSSDFEGIVVLTTKCLSCETITRQKQGMLDISVPVPISGYDNADLQDKPSTY------- 710
            |........:.|.            ...::|:|  |...|   ..:..|....:..|.
Mouse   768 EKEKKEDEKEKEA------------ENGKEKEG--DSLGP---GTHREAATPPREQTCGPEGSRS 815

  Fly   711 ---IQNSCITKEYFRGENKYSCNQCTGYTEAIRSISYEVLPRLLVIQLNRFSGGMEKV------- 765
               :.|..::.|....||:|.|..|....:|.:.:.....||.|::.|.|||..:..:
Mouse   816 VLDLVNYFLSPERLTAENRYYCESCASLQDAEKVVELSQGPRYLILTLLRFSFDLRTMRRRKILD 880

  Fly   766 STYVPTTFTLPCFCATCCELGEGNKLHVYKLYSVITHVGATLTVGHY------------------ 812
            ...:|....||.         .|.:...|.|.||:.|.|.:...|||
Mouse   881 DVTIPLLLRLPL---------AGGQGQAYDLCSVVVHSGVSSESGHYYCYAREGAARPAPVLGST 936

  Fly   813 ----------------IAYTCFLDLASDYVNCPKDRRNTMTNSQTMASQAVPSNENAAPNNGSSS 861
                            ::|:.|..:::.....|||....:...|.       ..|:.|...||..
Mouse   937 ERPEPENQWYLFNDTRVSYSSFESVSNVTSFFPKDTAYVLFYRQR-------PREDPAAEPGSPR 994

  Fly   862 VASTPVIAAASALA-SSGNI--LMKKMKFGRSKAS 893
            |.:.|.:......| |..|:  |.::.|..||:|:
Mouse   995 VRAEPTLHKDLMEAISKDNVLYLQEQEKEARSRAA 1029

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp1	NP_651687.3	Peptidase_C19	308..819	CDD:470612	106/577 (18%)
Usp35	XP_006507886.1	Peptidase_C19	505..979	CDD:470612	110/590 (19%)