Protein Alignment Usp1 and usp46

DIOPT Version :10

• Sequence 1: NP_651687.3
• Gene: Usp1 / 43462
• FlyBaseID: FBgn0028476
• Length: 1078
• Species: Drosophila melanogaster
• Sequence 2: NP_001231910.1
• Gene: usp46 / 100148916
• ZFINID: ZDB-GENE-070705-213
• Length: 370
• Species: Danio rerio
• Alignment Length: 561
• Identity: 99/561 - (17%)
• Similarity: 155/561 - (27%)
• Gaps: 270/561 - (48%)

  Fly   269 GSSSNEIE-----SQEPQSHQYYGPNGGSNAAGAGAGLNGSAAALNHAPSMGTLCNIGNSCYLNS 328
            |::::.:|     .|.|.:..|:|                             |.|.||:||.||
Zfish    13 GTNASALEKDIGPEQFPINEHYFG-----------------------------LVNFGNTCYCNS 48

  Fly   329 VVYTLRFAPHFLHNLHHLIQDLNVVQQTIVRQQTARSASLGKNVSAAQLEHARSWSSKDLATSTD 393
            |:..|.|...|..|:                                            ||....
Zfish    49 VLQALYFCRPFRENV--------------------------------------------LAYKVQ 69

  Fly   394 QYSGQNGGVNSGNGGSGSSKSTHQSVTEKLHELYNNLHGNEMADSTEPYHADTLLHAIQDVNATF 458
            |...:|                   :...|.:|::::...:......|  ....:..::..|..|
Zfish    70 QKKKEN-------------------LLTCLADLFHSIATQKKKVGVIP--PKKFISRLRKENDLF 113

  Fly   459 EGNQQQDAHEFLMCVLNCIRETNQSLIKAIGECPEVIANGYIANPDEVDTGEGQDRTDSTASQNL 523
            :...||||||||..:||.:.:..|
Zfish   114 DNYMQQDAHEFLNYLLNTVADILQ----------------------------------------- 137

  Fly   524 NAGNGSLATSQTTTTKTSFFSRKSKRKDEVKPSKSTRVQSPLKENSPTAGGITGAGTAHATANSL 588
                                   .:||.|             |:|    |.:...|||.||
Zfish   138 -----------------------EERKQE-------------KQN----GRLKNNGTAIAT---- 158

  Fly   589 FYLNTVDLSGASSTSGSASTSASGVVSTSAALPTPPQATKYSSDDEMNSATVLKDKMRLEERIRE 653
                                            .|.|:..|
Zfish   159 --------------------------------DTEPEQNK------------------------- 166

  Fly   654 LNLNFFSSDFEGIVVLTTKCLSCETITRQKQGMLDISVPVPISGYDNADLQDKPSTYIQNSCIT- 717
            ::..:....|:|.:...|:||:|||::.:.:..||:||.|.                 ||:.||
Zfish   167 IDPTWVHEIFQGTLTNETRCLNCETVSSKDEDFLDLSVDVE-----------------QNTSITH 214

  Fly   718 -------KEYFRGENKYSCNQCTGYTEAIRSISYEVLPRLLVIQLNRFSGGMEKVSTYVPTTF-- 773
                   .|....|.||.|..|....||.:.:..:.||.:|.:.|.||. .||::..|...::
Zfish   215 CLRDFSNTETLCSEYKYYCEMCCSKQEAQKRMRVKKLPMILALHLKRFK-YMEQLHRYTKLSYRV 278

  Fly   774 TLPCFCATCCELGEGNKL-HVYKLYSVITHVGATLTVGHYI 813
            ..|.........|:...| .:|.|.:|:.|.|:....||||
Zfish   279 VFPLELRLFNTSGDAVNLDRMYDLVAVVVHCGSGPNRGHYI 319

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp1	NP_651687.3	Peptidase_C19	308..819	CDD:470612	93/517 (18%)
usp46	NP_001231910.1	Peptidase_C19G	36..367	CDD:239128	94/538 (17%)