DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14507 and AgaP_AGAP003846

DIOPT Version :9

Sequence 1:	NP_001097964.1	Gene:	CG14507 / 43461	FlyBaseID:	FBgn0039655	Length:	373	Species:	Drosophila melanogaster
Sequence 2:	XP_310404.4	Gene:	AgaP_AGAP003846 / 1271582	VectorBaseID:	AGAP003846	Length:	523	Species:	Anopheles gambiae

Alignment Length:	503	Identity:	160/503 - (31%)
Similarity:	219/503 - (43%)	Gaps:	179/503 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 GQASGAANVTVIEDIRSAFRGVTNDTELLNHIIPEMYGASMRSANPSFVFKMPSKSNGGGDDFEL 80
            |.....:::..|.:||.  ...|.|:.||:..       ::.:.||::||.:|.:   |.:....
Mosquito    49 GPTKMKSHIKRILNIRE--ENSTLDSYLLSLF-------NVDNLNPTYVFLLPME---GKNHVRK 101

  Fly    81 LTMQRSDFAEPIFPNISQSATAIDSPSTIPPETSVKTSLMVSPQQD------------------- 126
            |..|||||.|..|||:    |.|:..|..|..|.  .|::..|..|
Mosquito   102 LIYQRSDFEEAEFPNV----TTINKFSGRPNRTG--ASIVACPGSDMQLEKKIFDHLDKDTMDDG 160

  Fly   127 ----------------------------------------------------------------- 126

Mosquito   161 TRKVVEENVRTERNFIKFMDELNRDLEEEENRRMLKESMRKSASTAGRTSSTALFTPYAYKHTPT 225

  Fly   127 --WQQMGLDGWTGELKPPVASLEQDHRDTRPPISW-QNSYPHDEIRLEFQNHHFD-------GRV 181
              |..:||:||.|.|:.     ...||...|.:.. :.::.....:|:..   |:       ||.
Mosquito   226 IGWDDLGLEGWAGGLRE-----NHGHRFDHPVLEKPKTTFAPQTTQLQAS---FNAAQQLPSGRP 282

  Fly   182 T--------------------------------DIRVITQ-----------------TTSKPAEM 197
            |                                |:.|..|                 |.|:.|..
Mosquito   283 TAALGPASKATVNQTVVASAAARYKQTGVLLSEDVGVKLQEIYKRTNGSNARIKWPITNSRDAHR 347

  Fly   198 EDLMNVQNVYIARVNDPFGYSMKWSFTNDSSREKELLPE-----GDRGKRDVARLYSMIKCSTGC 257
            :     ::|:|||.|:|||:|.||.::|::.:|..|..|     ..|.||.|..|||||||:|||
Mosquito   348 D-----EDVFIARANNPFGHSTKWRWSNETEQEDPLKVEVQSSRDGRAKRGVYNLYSMIKCATGC 407

  Fly   258 DPLIYKGYGCYCGFGGHGVPADGIDRCCRVHDKCYGQSNCISYLEYFVPYVWKCYRGKPLCAVDH 322
            ||||||||||||||.|.|...|||||||::||.||..::|..:|||||||:||||||:||||:||
Mosquito   408 DPLIYKGYGCYCGFLGSGQALDGIDRCCKMHDYCYSTASCPMFLEYFVPYLWKCYRGRPLCAIDH 472

  Fly   323 GEFGGPDSCAARLCQCDLRLSRCLKRYYCPHRRSICHSSRSRRLQNLI 370
            ||:|||.|||:|||.|||.||:||:|||||.:|::|.:|..|.||||:
Mosquito   473 GEWGGPGSCASRLCHCDLSLSKCLRRYYCPRKRNVCTTSPLRLLQNLV 520

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14507	NP_001097964.1	PLA2c	243..357	CDD:153091	82/113 (73%)
AgaP_AGAP003846	XP_310404.4	PLA2c	393..506	CDD:153091	81/112 (72%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	194	1.000	Domainoid score	I6654
eggNOG	1	0.900	-	-		E1_KOG4087
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	285	1.000	Inparanoid score	I5240
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000342
OrthoInspector	1	1.000	-	-		oto108944
Panther	1	1.100	-	-	LDO	PTHR11716
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X246
TreeFam	1	0.960	-	-
	10	9.920