Protein Alignment Brd8 and GCN5

DIOPT Version :9

• Sequence 1: NP_651685.2
• Gene: Brd8 / 43460
• FlyBaseID: FBgn0039654
• Length: 872
• Species: Drosophila melanogaster
• Sequence 2: NP_011768.1
• Gene: GCN5 / 853167
• SGDID: S000003484
• Length: 439
• Species: Saccharomyces cerevisiae
• Alignment Length: 555
• Identity: 104/555 - (18%)
• Similarity: 176/555 - (31%)
• Gaps: 159/555 - (28%)

  Fly   310 ASTTPTLERSPSQAAPTLSMLLEKNMAAAKANESGSLVKPEGSGNQEQGVDEATSSAAGTADSDE 374
            |:|.|.::|          :.||.|:...:. |.....|.||:..:.:|..|..:...|.:
Yeast    15 ATTDPEVKR----------VKLENNVEEIQP-EQAETNKQEGTDKENKGKFEKETERIGGS---- 64

  Fly   375 ADPNEAQLLEVFKNIDQIIDDIDID--------MASVIDDEILKNVDDVVASPSNDKAEVIDFED 431
                     ||..::::.|...:.|        ..||:::...| ::..|.:..|.|..::
Yeast    65 ---------EVVTDVEKGIVKFEFDGVEYTFKERPSVVEENEGK-IEFRVVNNDNTKENMM---- 115

  Fly   432 KLDALKREQSKSSPASDKPKSVELVIGSSDDSNDNI--PLAAVASQESKDRGQSGGESTRGTEDA 494
            .|..||....|..|...|.....||...|..|...|  ||..|           ||.:.|..:.
Yeast   116 VLTGLKNIFQKQLPKMPKEYIARLVYDRSHLSMAVIRKPLTVV-----------GGITYRPFDK- 168

  Fly   495 ESEPLTSEVAVEEIGETITIISTSSEDTAGSPPTKMEEDGATDSLPKKEDAAEDKSEQESSSQGQ 559
                       .|..|.:....:|:|...|.....|..  ..|.:....:.....:..::.:.|.
Yeast   169 -----------REFAEIVFCAISSTEQVRGYGAHLMNH--LKDYVRNTSNIKYFLTYADNYAIGY 220

  Fly   560 NKAGGSTDEPELIDHQATREAQSKSGKDTAGKPVTMQEKTTTQSAPVPVDLHDTDEESSSLTDSS 624
            .|..|.|.|                  .|..|.:.|.              :..|.|..:|...|
Yeast   221 FKKQGFTKE------------------ITLDKSIWMG--------------YIKDYEGGTLMQCS 253

  Fly   625 -----KHDDHPRSAKAKPPALKLALDD-SKSELELSGTPQ-------PPSAPARTPLLRKLPHRD 676
                 ::.|..:....:..||:..:.. |||.:...|..|       .|..|...|.|::
Yeast   254 MLPRIRYLDAGKILLLQEAALRRKIRTISKSHIVRPGLEQFKDLNNIKPIDPMTIPGLKE----- 313

  Fly   677 RSESPMVDDDATTASDHSTARSTRRRCSSTPVIDSIPNSPASSEHTDDRRETRAASKKLFLSIYA 741
                                      ...||.:|::...|....|.       ||.:.:...:
Yeast   314 --------------------------AGWTPEMDALAQRPKRGPHD-------AAIQNILTEL-- 343

  Fly   742 MLLDSKHAA--PFKRPFHDEHAQRHADLCLRPMDFPTIKRNIDSGFIRSLSELHRDVLLMAHNVL 804
                ..|||  ||.:|.:.|....:.|....|||..|::..::|...:.:.:...|..|:.:|..
Yeast   344 ----QNHAAAWPFLQPVNKEEVPDYYDFIKEPMDLSTMEIKLESNKYQKMEDFIYDARLVFNNCR 404

  Fly   805 VAYKPHTAQHKTA----RLFVQDCQAIKEFSQLPD 835
            :....:|:.:|.|    :.|....:.|.|:|.|.|
Yeast   405 MYNGENTSYYKYANRLEKFFNNKVKEIPEYSHLID 439

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Brd8	NP_651685.2	PaaSYMP	<105..188	CDD:291408
		PHA03249	402..>582	CDD:223023	35/181 (19%)
		Bromo_brd8_like	729..833	CDD:99939	25/109 (23%)
GCN5	NP_011768.1	COG5076	77..439	CDD:227408	86/467 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900