Protein Alignment Brd8 and RSC1

DIOPT Version :9

• Sequence 1: NP_651685.2
• Gene: Brd8 / 43460
• FlyBaseID: FBgn0039654
• Length: 872
• Species: Drosophila melanogaster
• Sequence 2: NP_011570.1
• Gene: RSC1 / 852947
• SGDID: S000003288
• Length: 928
• Species: Saccharomyces cerevisiae
• Alignment Length: 711
• Identity: 127/711 - (17%)
• Similarity: 220/711 - (30%)
• Gaps: 273/711 - (38%)

  Fly    36 DQNWITVSRTLKTICGN--GSSNRPADWFS---QKNCAMQYGNLLESVEATKRKKRSSESSAGVS 95
            |||    ::|| |:|..  ...|....::|   ...|.|.....::|     ||.|:..
Yeast   253 DQN----NKTL-TLCFEKLPDRNEEPTYYSVITDPICLMDIRKKVKS-----RKYRNFH------ 301

  Fly    96 SPATVETPTELLLRRL----TEERQAEIKAQMRQDQETYRRIQR-EIESLQSDAVTEQELQ---- 151
               |.|...:|:|...    ::::...|:||:.  ::.:.|:.| |:.....|.:.|.||:
Yeast   302 ---TFEEDFQLMLTNFKLYYSQDQSNIIRAQLL--EKNFNRLVRIELSKPDEDYLPEGELRYPLD 361

  Fly   152 ----------------------------------------DMWLE----IEKEQEARRIEEMKLE 172
                                                    :.||.    ...||...|::.:..:
Yeast   362 DVEINDEKYQIGDWVLLHNPNDINKPIVGQIFRLWSTTDGNKWLNACWYFRPEQTVHRVDRLFYK 426

  Fly   173 NRMREREQRKKDLASNWRNSSLAV--KRSNQAADTTSV--------------------------- 208
            |.:.:..|.:.....:.:.....:  .|..:...:|.|
Yeast   427 NEVMKTGQYRDHPIQDIKGKCYVIHFTRFQRGDPSTKVNGPQFVCEFRYNESDKVFNKIRTWKAC 491

  Fly   209 ------DMDVEDINTSGNGKQQTGPSPL---------LTSLLKSPTGNAPATPTPGGAAPAAGGT 258
                  |.|...|..:|. |....|||:         |...:..||..||..|      |..|..
Yeast   492 LPEELRDQDEPTIPVNGR-KFFKYPSPIADLLPANATLNDKVPEPTEGAPTAP------PLVGAV 549

  Fly   259 ---------------------------------GSVARATAPTITSLLTSGPSSAVANQPVITMK 290
                                             |.:...|...||..||:.....|.:..  |::
Yeast   550 YLGPKLERDDLGEYSTSDDCPRYIIRPNDPPEEGKIDYETGTIITDTLTTSSMPRVNSSS--TIR 612

  Fly   291 SPTDAAFMSRPITGPPASEASTTPTLERSPSQAAPTLSMLLEKNMAAAKAN-------------- 341
            .||.....|.|.:...:|  |.||.|.::.:|   |.:.|..:||..:..|
Yeast   613 LPTLKQTKSIPSSNFRSS--SNTPLLHQNFNQ---TSNFLKLENMNNSSHNLLSHPSVPKFQSPS 672

  Fly   342 --ESGSLVKPEGSGNQEQGVDEATSSAAG------------TADSDEADPNEAQL---------L 383
              |..|..|...:..|.|....|....|.            ||.:.:.:.|...:         :
Yeast   673 LLEQSSRSKYHSAKKQTQLSSTAPKKPASKSFTLSSMINTLTAHTSKYNFNHIVIEAPGAFVVPV 737

  Fly   384 EVFKNIDQI---------------------IDDIDIDMASV---------IDDEILKNVDDVVAS 418
            .:.|||..|                     |:||:.....:         |.:.::.:.:|:|..
Yeast   738 PMEKNIRTIQSTERFSRSNLKNAQNLGNTAINDINTANEQIIWFKGPGVKITERVIDSGNDLVRV 802

  Fly   419 PSN-----DKAEVIDFEDKLDALKREQSKSSPASD-----------KPKSVEL-----VIGSSDD 462
            |.|     :|...:|:||      .|:....|.:|           .|.|:.|     :..||::
Yeast   803 PLNRWFCKNKRRKLDYED------IEEDVMEPPNDFSEDMIANIFNPPPSLNLDMDLNLSPSSNN 861

  Fly   463 SNDNIPLAAVASQESKDRGQSGGESTRGTEDA--ESEPLTSEVAVEEIGETITI-ISTSSE 520
            |::.:.|:.:||      |.:.|:.....|::  |:|....|..:|:|..|... :::|:|
Yeast   862 SSNFMDLSTIAS------GDNDGKECDTAEESEDENEDTEDEHEIEDIPTTSAFGLNSSAE 916

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Brd8	NP_651685.2	PaaSYMP	<105..188	CDD:291408	19/135 (14%)
		PHA03249	402..>582	CDD:223023	32/152 (21%)
		Bromo_brd8_like	729..833	CDD:99939
RSC1	NP_011570.1	Bromo_Rsc1_2_I	8..113	CDD:99952
		COG5076	115..463	CDD:227408	37/230 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900