Protein Alignment Brd8 and RSC2

DIOPT Version :9

• Sequence 1: NP_651685.2
• Gene: Brd8 / 43460
• FlyBaseID: FBgn0039654
• Length: 872
• Species: Drosophila melanogaster
• Sequence 2: NP_013461.1
• Gene: RSC2 / 851071
• SGDID: S000004349
• Length: 889
• Species: Saccharomyces cerevisiae
• Alignment Length: 652
• Identity: 118/652 - (18%)
• Similarity: 192/652 - (29%)
• Gaps: 232/652 - (35%)

  Fly   126 DQETYRRIQREIESLQSDAVTEQELQDMWLEIEKEQEARRIEEMKLENRMREREQRKKDLASNWR 190
            |:..|...|:::.                   ||.:|..|....:.|:   .......:.|...|
Yeast   138 DEPGYEEFQQKLR-------------------EKAEEVARANAARAES---SSSMNSTEAARRLR 180

  Fly   191 NSSLAVKRSNQAADTTSVDMDVE----DINTSGNGKQQTGPSPLLTSLL-------------KSP 238
            .:..:|||.::....|:.|.|.|    ||:   |.|....|..:...|:             :|.
Yeast   181 KTRTSVKRESEPGTDTNNDEDYEATDMDID---NPKDADFPDLIRKPLININPYTRKPLRDNRST 242

  Fly   239 TGNAPATPTPGGAAPAAGGTGSVARATAPTI----------------TSLLTSG----------- 276
            |.:...||.|.|..........|.|...|.|                ..:|.||
Yeast   243 TPSHSGTPQPLGPRHRQVSRTQVKRGRPPIIDLPYIQRMKNVMKVLKKEVLDSGIGLTDLFERLP 307

  Fly   277 --------------PSSAV-ANQPVITMKSPTDAAFMSRPITGPPASEASTTPTLERSPSQAAP- 325
                          |.|.. .|:.|.|.:..|...|.         ::.:...|..|...:..|
Yeast   308 DRHRDANYYIMIANPISLQDINKKVKTRRYKTFQEFQ---------NDFNLMLTNFRISHRGDPE 363

  Fly   326 --TLSMLLEKNMAAAKANESGSLVKPEGS----GNQEQGVDEATSS---------AAGTADSDEA 375
              .:|.:|||...:....|   |.||:.|    |.....:||...:         |.....:|..
Yeast   364 SIKISNILEKTFTSLARFE---LSKPDRSFIPEGELRYPLDEVIVNNISYHVGDWALLRNQNDPQ 425

  Fly   376 DPNEAQLLEVFKNID--------------QIIDDIDIDMASVIDDEILK--NVDDVVASPSNDKA 424
            .|...|:..::|..|              |.:..:|   .....:|::|  ...|.:.|....|.
Yeast   426 KPIVGQIFRLWKTPDGKQWLNACWYYRPEQTVHRVD---RLFYKNEVMKTGQYRDHLVSNLVGKC 487

  Fly   425 EVIDF-------------------------EDKL------------DALKREQSKSSPASDK--- 449
            .||.|                         .||:            :.::.....:.|.:.:
Yeast   488 YVIHFTRYQRGNPDMKLEGPLFVCEFRYNESDKIFNKIRTWKACLPEEIRDLDEATIPVNGRKFF 552

  Fly   450 --PKSVELVIGSSDDSNDNIPLAAVASQESKDRGQSGGESTRGTEDAESEPLTSEVAV------E 506
              |..:..::.::...:|.:|                 |.|.|:.||  .||...|.:      :
Yeast   553 KYPSPIRHLLPANATPHDRVP-----------------EPTMGSPDA--PPLVGAVYMRPKMQRD 598

  Fly   507 EIGETITIISTSSEDTAGSP-----PTKMEEDGATD--------------SLPKKEDAAEDKSEQ 552
            ::||..|     |:|   .|     |....|:|..|              :|||     ...|..
Yeast   599 DLGEYAT-----SDD---CPRYIIRPNDSPEEGQVDIETGTITTNTPTANALPK-----TGYSSS 650

  Fly   553 ESSSQGQNKAGGSTDEPELIDHQATREAQSKSGKDTAGKPVTMQEKTTTQSAPVPVDLHDTDEES 617
            :.||...|::..|.:....|..|  :...|:.|...||.|:|:|.....|...:....|...::.
Yeast   651 KLSSLRYNRSSMSLENQNAIGQQ--QIPLSRVGSPGAGGPLTVQGLKQHQLQRLQQQQHQYQQQK 713

  Fly   618 SS 619
            .|
Yeast   714 RS 715

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Brd8	NP_651685.2	PaaSYMP	<105..188	CDD:291408	9/61 (15%)
		PHA03249	402..>582	CDD:223023	42/248 (17%)
		Bromo_brd8_like	729..833	CDD:99939
RSC2	NP_013461.1	Bromo_Rsc1_2_I	17..121	CDD:99952
		COG5076	123..503	CDD:227408	74/404 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900