DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Brd8 and AT3G60110

DIOPT Version :9

Sequence 1:	NP_651685.2	Gene:	Brd8 / 43460	FlyBaseID:	FBgn0039654	Length:	872	Species:	Drosophila melanogaster
Sequence 2:	NP_567092.4	Gene:	AT3G60110 / 825181	AraportID:	AT3G60110	Length:	641	Species:	Arabidopsis thaliana

Alignment Length:	709	Identity:	135/709 - (19%)
Similarity:	243/709 - (34%)	Gaps:	220/709 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 WSKREQLILASAVSCSGDQNWITVSRTLKTICGNGSSNRPADWFSQKNCAMQYGNLLESVEATKR 83
            |...|:|:|..||......:|.:|::.::      :.:|.:...|..||.::|.:|       ||
plant    52 WGTWEELVLTCAVKRHAFSDWDSVAKEVQ------ARSRSSLIVSAVNCRLKYQDL-------KR 103

  Fly    84 KKRSSESSAGVSSPATVETPTEL----LLRRLTEERQAEIKAQMRQDQETYRRIQREIESLQ--- 141
            :.:.|......::.|......|:    .|.:|.....||::.::::..::...:|.:::.|:
plant   104 RFQDSVDVGDENTEAAANEEDEVGEISWLEQLRSLHMAELRREVQRCDDSILSLQLKVKKLEEEK 168

  Fly   142 --SDAVTEQELQDMWLEIEKEQEARRIEEMKLENRMREREQRKKDLASNWRNSSLAVKRSNQAAD 204
              .|...:.:|        |..|.:.:.    .||......|..:.:.|..||:.:|   ::.||
plant   169 DGDDGDNKPDL--------KNDETKPVR----VNRETTESDRDDNRSMNESNSTASV---DKIAD 218

  Fly   205 TTSVDMD--VEDINTSGN------GKQQTGPSPLLTSLLKSPTGNAPATPTPG---------GAA 252
            ...:|.|  |:....|.|      .|.:|......|...:|...|:......|         |..
plant   219 HDRLDGDKMVKANENSRNPDPDPVNKAETPEEEERTVSKRSEMSNSGELDESGTSNCLGKRKGQK 283

  Fly   253 PAAGGTGSVARATAPTITSLLTSGPSSAVANQPVITM-----KSPTDAAFMSRPITGPPASEAST 312
            ..:||.|...:              |:...:||:|.:     ..|..:.|.||       ..:..
plant   284 YRSGGGGGGVK--------------SAGDKSQPLIDIIKLIRSHPRGSVFESR-------LRSQD 327

  Fly   313 TPTLERSPSQAAPTLSM-LLEKNMAAAKANESGSLVKPEGSGNQEQG-------VDEATSSAAGT 369
            |...:|...|   .|.| .:||.|      |.||.|....|..::..       |...|||:...
plant   328 TKDYKRLIRQ---HLDMKTIEKKM------EKGSYVSSSLSFYRDLKLLFTNAIVFFPTSSSESI 383

  Fly   370 ADSDEADPNEAQLLEVFKNIDQIIDDIDIDMASVIDDEILKNV---------DDVVASPSNDKAE 425
            |         ||                 ::.:::.:|:.|..         .:..:|.|..|:.
plant   384 A---------AQ-----------------ELRTLVSNEMKKRTGKLGHCVIKSEAESSVSRQKSS 422

  Fly   426 VIDF---EDKLDALKR-EQSKSSPASDKPKSVELVIGSSDDSNDNIPLAAVASQESKDRGQSGGE 486
            |:..   :.|..|||: ..|.||...|:.||.|:       |.:.|                  .
plant   423 VLSLVPCKKKSSALKKTSPSSSSRQKDEKKSQEV-------SEEKI------------------V 462

  Fly   487 STRGTEDAESEPLTSEVAVEEIGETITIISTSSEDTAGSPPTKMEEDGATDSLPKKEDAAEDKSE 551
            :|..|..|.|...||        :.|.:::..::........|.:.|..|:|....:|..|:.|:
plant   463 TTTATTSARSSRRTS--------KEIAVVAKDTKTGRAKNNIKKQTDTKTESSDDDDDEKEENSK 519

  Fly   552 ----------------------------QESSSQGQNKAGGSTDEPELIDHQATREAQSKSGKDT 588
                                        :|::|:.|.|..|:..:..  |||...:...|. :::
plant   520 TEKKTVADKKKSVADFLKRIKKNSPQKGKETTSKNQKKNDGNVKKEN--DHQKKSDGNVKK-ENS 581

  Fly   589 AGKPVTMQEKTTTQSAPVPVDLHDTDEESSSL----------------TDSSKHDDHPR 631
            ..||..::..|..:.    |::.:.:.:|||.                .:|.|.|..||
plant   582 KVKPRELRSSTGKKK----VEVENNNSKSSSKRKQTKETAEVATGKRGRESGKDDKQPR 636

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Brd8	NP_651685.2	PaaSYMP	<105..188	CDD:291408	14/91 (15%)
		PHA03249	402..>582	CDD:223023	41/220 (19%)
		Bromo_brd8_like	729..833	CDD:99939
AT3G60110	NP_567092.4	SANT	49..104	CDD:197842	15/64 (23%)
		BROMO	300..398	CDD:197636	28/139 (20%)
		PTZ00121	<430..>638	CDD:173412	48/247 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR15398
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100