Protein Alignment Brd8 and Brd3

DIOPT Version :9

• Sequence 1: NP_651685.2
• Gene: Brd8 / 43460
• FlyBaseID: FBgn0039654
• Length: 872
• Species: Drosophila melanogaster
• Sequence 2: NP_001107046.1
• Gene: Brd3 / 67382
• MGIID: 1914632
• Length: 743
• Species: Mus musculus
• Alignment Length: 566
• Identity: 116/566 - (20%)
• Similarity: 193/566 - (34%)
• Gaps: 132/566 - (23%)

  Fly   242 APATPTPGGAAPAAGGTGSVARATAPTITSLLTSGPSSAVA-----NQPVITMKSPTDAAFMSRP 301
            :||||.. ...|....|..:|....||||:.:||.|....|     ..|::.:..||......:.
Mouse   177 SPATPFQ-NIPPTVSQTPVIAATPVPTITANVTSVPVPPPAAPPPPATPIVPVVPPTPPVVKKKG 240

  Fly   302 ITGPPASEASTTPTLERSPSQAAPTLSMLLEKNMA--AAKANESGSLVKP------EGSGNQEQG 358
            :.....:...||..:..|.|::.|.||   |...|  .|:....|..:||      :|...|..|
Mouse   241 VKRKADTTTPTTSAITASRSESPPPLS---EPKQAKVVARRESGGRPIKPPKKDLEDGEVPQHAG 302

  Fly   359 VDEATSSAAGTADSDEAD---------------PNEAQLLEVFKNIDQIIDDIDIDMASVIDDEI 408
            .....|......||...:               |.:|:.||:....|.|...:|:       ..:
Mouse   303 KKGKLSEHLRHCDSILREMLSKKHAAYAWPFYKPVDAEALELHDYHDIIKHPMDL-------STV 360

  Fly   409 LKNVD------------DVVASPSN------DKAEVIDFEDKLD-------ALKREQSKSSPASD 448
            .:.:|            |:....||      ...||:....||.       |...::...:||..
Mouse   361 KRKMDSREYPDAQGFAADIRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPMEAPALP 425

  Fly   449 KPKSVELVIGSSDDSNDNIPLAAVASQESKDRGQSGGESTRGTEDAESEPLT------------S 501
            .| :..:|...::.|..       :.:.|.|.|.|..|..|.|..||.:..|            |
Mouse   426 AP-TAPIVSKGAESSRS-------SEESSSDSGSSDSEEERATRLAELQEQTGCGAFQDQLLNVS 482

  Fly   502 EVAVEEIGETITIISTSSEDTAGSPPTKMEEDGATDSLPKKEDAAEDKSEQESSSQGQNKAGGST 566
            .|.::.:.|.:..:|.:..    :.|.|.:|....:...|.:|..::|.:.::.|:.:.||..:
Mouse   483 SVQLKAVHEQLAALSQAPV----NKPKKKKEKKEKEKKKKDKDKDKEKEKHKAKSEEEKKAKAA- 542

  Fly   567 DEPELIDHQATREAQSKSGKDTAGKPVTMQEKTTTQSAPVPVDLHDTDEESSSLTDSSKHDDHPR 631
                    .|.::||.|..      |......|||.|.    .|....:::|:..||.:.::
Mouse   543 --------PAAKQAQQKKA------PTKKANSTTTASR----QLKKGGKQASASYDSEEEEE--- 586

  Fly   632 SAKAKPPALKLALDDSKSELELSGTPQPPSAPARTPLLRKLPHRDRSESPMVDDD--ATTASDHS 694
                   .|.::.|: |.:|.|.....|...      |.::.|..:|..|.:.|.  .....|..
Mouse   587 -------GLPMSYDE-KRQLSLDINRLPGEK------LGRVVHIIQSREPSLRDSNPDEIEIDFE 637

  Fly   695 TARSTRRRCSSTPVIDSI------PNSPASSEHTDDRRETRAASKK 734
            |.:.|..|.....|...:      |.|.:..:.....:|..|..||
Mouse   638 TLKPTTLRELERYVKSCLQKKQRKPLSTSGKKQAAKSKEELAQEKK 683

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Brd8	NP_651685.2	PaaSYMP	<105..188	CDD:291408
		PHA03249	402..>582	CDD:223023	39/216 (18%)
		Bromo_brd8_like	729..833	CDD:99939	3/6 (50%)
Brd3	NP_001107046.1	Bromo_Brdt_I_like	33..139	CDD:99929
		Bromo_Brdt_II_like	310..411	CDD:99930	17/107 (16%)
		BET	589..653	CDD:374956	15/70 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900