Protein Alignment Brd8 and brd8b

DIOPT Version :9

• Sequence 1: NP_651685.2
• Gene: Brd8 / 43460
• FlyBaseID: FBgn0039654
• Length: 872
• Species: Drosophila melanogaster
• Sequence 2: XP_017214481.1
• Gene: brd8b / 337414
• ZFINID: ZDB-GENE-030722-10
• Length: 864
• Species: Danio rerio
• Alignment Length: 942
• Identity: 247/942 - (26%)
• Similarity: 399/942 - (42%)
• Gaps: 224/942 - (23%)

  Fly     1 MSAGVQERLQLSRMPLDTWSKREQLILASAVSCSGDQNWITVSRTLKTICGNGSSNRPADWFSQK 65
            ||.|:.:...||..|.:.||.||:|.|||:|..||||||::|||.:|..   ..|.||.||||||
Zfish     1 MSTGMGKHKMLSLGPTEPWSIREKLCLASSVMRSGDQNWVSVSRAIKPF---SESGRPPDWFSQK 62

  Fly    66 NCAMQYGNLLESVEATKRKKRSSESSAGVSSPATVETPTELLLRRLTEERQAEIKAQMRQDQETY 130
            :||.||..|||:.||.|||:.....        .|||..::::||||.||..|:|..::..||.|
Zfish    63 HCASQYSQLLETTEAPKRKRGEKGE--------VVETIEDVIVRRLTAERIEELKRLIKDTQEKY 119

  Fly   131 RRIQREIESLQSDAVTEQELQDMWLEIE--KEQEARRIEEMKLENRMREREQRKKDLASNW--RN 191
            |::::|::.:|:..| :.:|:::|.|||  |:||....|:.|   |..|...:.:..|.|.  |.
Zfish   120 RKLKKEVDLIQAGHV-DPKLEELWAEIELKKKQEEEEAEQKK---RATEAAYQIRQAAKNTPKRV 180

  Fly   192 SSLAVKRSNQAADTTSVD--------------------------MDVEDINTSGNGKQQTGPSPL 230
            .|:.| ||...|.:.|:|                          |.|.|:  .|.|.:::|.|.|
Zfish   181 PSVTV-RSPPGASSPSMDILQPDASQPMTDESCASPMAQGVTVFMPVSDV--MGPGPKESGLSSL 242

  Fly   231 LTSLLKSPTGN--AP-ATPTPGGAAPAAGGTGSVARATAPTITSLLTSGPSSAVANQPVITMKSP 292
            :..   ||...  || |||.|                 :|.::.||..|...|.:::.|:..:..
Zfish   243 VDD---SPQKKHLAPKATPPP-----------------SPLLSELLKKGSLIAASSRLVVEGEVA 287

  Fly   293 TDAAFMSRPITGPPASEASTTPTL---ERSPSQAAPTLSMLLEKNMAAAK--------------- 339
            |..:      .|..|.|..|:.|:   .:..:..|||||.|||....|.:
Zfish   288 TGLS------NGSHAVELHTSATVLPATQDITADAPTLSRLLESVTPAQQPVSADPPKPPTVVPP 346

  Fly   340 ------ANESGSLVKPEGSGNQEQGVDEATSSAAGTADSDEADPNEAQLLEVFKNIDQIIDDIDI 398
                  ..:||.....||||        |.:..||::...|.:..|.:|:|         :|..:
Zfish   347 APDHLSVPKSGDAAIAEGSG--------AEAVMAGSSTPAEVEGKETELVE---------EDTVV 394

  Fly   399 DMASVIDDEILKNVDDVVASPSNDKAEVIDFEDKLDALKREQSKS---SPASDKPKSVELVIG-- 458
            .::.:..:..|:.|.|::|.   .:.:|.|..:.|||...|.:.|   .||          :|
Zfish   395 SVSYMGHELDLETVGDIIAI---IEEKVDDPVEALDAAAVEAALSLCEDPA----------VGGH 446

  Fly   459 --SSDDSNDNIPLAAVASQESKDRGQSGGESTRGTEDAESEPLTSEVAVEEIGETITIISTSSE- 520
              :|...:.....|.......:....:|.||...:...:.|   .||.|||..||..:...:.|
Zfish   447 PLTSPWESQTFKAAEPEPMIQQSAIPAGAESAPNSAIVQGE---MEVLVEEATETEAVEGVTEEP 508

  Fly   521 DTAGSPPTKMEEDGATDSLPKKEDAAEDKSEQESSSQGQNKAGGSTDEPELIDHQATREAQSKSG 585
            :...:|.|:..:|            :|.|:|.|...:|:    |..:|....:::....|....|
Zfish   509 EVPSAPETEQSQD------------SEVKTEVERGGEGE----GGVEETAQPENRTPSPAVKCEG 557

  Fly   586 KDTAGKPVTMQEKTTTQSAPVPVDLHDTDEESSSLTDSSKHDDHPRSAKAKPPALKLALDDSKSE 650
            :|      .:|.:|.|...       |:::.|:|..|:       :..|.:....::.:|:. .|
Zfish   558 ED------WVQPETVTPCL-------DSEDSSASAKDA-------KEVKEEDGGSEVDVDEG-ME 601

  Fly   651 LELSGTPQPPSAPARTPLLRKLPHRDRSESPMVDDDATTASDHSTARSTRRRCSSTPVIDSIPNS 715
            ::..|     ......|.|.:           ||..|:.:.|...:.|.|...:     ||..:|
Zfish   602 MKECG-----DGDGEGPYLSE-----------VDPPASESEDGYGSHSQRYTTA-----DSTASS 645

  Fly   716 PASSEH---TDDRRETRAAS--KKLFLSIYAMLLDSKHAAPFKRPFHDEHAQRHADLCLRPMDFP 775
            ||||:.   ::|:...:|..  ||..:.::....:.::|:.|.:|..|:.|..:..:..||||..
Zfish   646 PASSQFSMCSEDQEALQAQKIWKKAIMLVWRAAANHRYASVFLQPVSDDIAPGYHSIVHRPMDLS 710

  Fly   776 TIKRNIDSGFIRSLSELHRDVLLMAHN-VLVAYKPHTAQHKTARLFVQDCQAIKEF--SQL--PD 835
            .||:||:||.||:.:|..||::||..| |:.....|...|....:.....:.|::|  :||  ..
Zfish   711 AIKKNIESGQIRTTAEFQRDIMLMFQNAVMYNSSDHDVYHMALEMQRDVLEQIQQFLATQLIMQT 775

  Fly   836 VQAGITATPVSNTGSLRADKSSGSKARSGSRK 867
            .::||      :|.|||        .|..:||
Zfish   776 SESGI------STKSLR--------GREANRK 793

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Brd8	NP_651685.2	PaaSYMP	<105..188	CDD:291408	28/84 (33%)
		PHA03249	402..>582	CDD:223023	39/187 (21%)
		Bromo_brd8_like	729..833	CDD:99939	31/108 (29%)
brd8b	XP_017214481.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170595295
Domainoid	1	1.000	151	1.000	Domainoid score	I4318
eggNOG	1	0.900	-	-		E1_COG5076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	195	1.000	Inparanoid score	I3810
OMA	1	1.010	-	-		QHG46231
OrthoDB	1	1.010	-	-		D1509761at2759
OrthoFinder	1	1.000	-	-		FOG0004061
OrthoInspector	1	1.000	-	-		otm24393
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR15398
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X5075
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	11	10.960