DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Brd8 and brd2a

DIOPT Version :9

Sequence 1:	NP_651685.2	Gene:	Brd8 / 43460	FlyBaseID:	FBgn0039654	Length:	872	Species:	Drosophila melanogaster
Sequence 2:	NP_571275.2	Gene:	brd2a / 30445	ZFINID:	ZDB-GENE-990415-248	Length:	836	Species:	Danio rerio

Alignment Length:	362	Identity:	85/362 - (23%)
Similarity:	124/362 - (34%)	Gaps:	81/362 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   569 PELIDHQATREAQSKSGKDTAGKPVTMQEKTTTQSAPVPVDLHDTDEESSSLTDSSKHDDHPRSA 633
            ||:.:.......:.|..|...|:.:.....||....|....|       |.|..|....|.|.|.
Zfish   179 PEVEEEIPAPVPRGKQSKPKKGQKLFSGGITTAHQVPAISSL-------SQLAYSPPTPDTPDSV 236

  Fly   634 KAKPPALKLALDDSKSELELSGTPQ----PPSAP------------ARTPLLRKLP--------- 673
            .:.||  :..:..:.....|..||.    ||:.|            ..||....:|
Zfish   237 LSTPP--QTLITKNFPPPPLHSTPALLGLPPTQPTAKKKGVKRKADTTTPTTTVMPLTLGVGGMG 299

  Fly   674 --------------HRDRSESPMVDDDATTASDHSTARS----------TRRRCSSTPVIDSIPN 714
                          .....:||:...:....|..|.:.|          .||..|..|:.....:
Zfish   300 MGMGMGMSMGMGMGMGLGGDSPLTLSNMGMDSKQSLSLSLGMSLEDKVPARRGGSGRPIKPPRKD 364

  Fly   715 SPAS-SEHTDDRRETRAASKKLFLSIYAMLLDSKHAA---PFKRP-------FHDEHAQRHADLC 768
            .|.| ::|...||...:...:...:|...||..||.|   ||.:|       .||     :.|:.
Zfish   365 LPDSQNQHQPVRRGKLSQQLRYCSTILKELLSKKHTAYAWPFYKPVDVSSLGLHD-----YYDII 424

  Fly   769 LRPMDFPTIKRNIDSGFIRSLSELHRDVLLMAHNVLVAYKPHTAQHKTARLF--VQDCQAIKEFS 831
            :.|||..||||.:|....|...:...||.||..|   .||.:...|....:.  :||....: |:
Zfish   425 MYPMDLSTIKRKMDHREYRDALQFAADVRLMFSN---CYKYNPPDHDVVAMARRLQDVFEFR-FA 485

  Fly   832 QLPDVQAGITATPVSNTGSLRADKSSGSKARSGSRKS 868
            ::|| :...:..|.|..|.|..|.||.|.:.|.|.:|
Zfish   486 KMPD-EPLESLPPASLGGGLGGDSSSSSSSSSSSSES 521

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Brd8	NP_651685.2	PaaSYMP	<105..188	CDD:291408
		PHA03249	402..>582	CDD:223023	2/12 (17%)
		Bromo_brd8_like	729..833	CDD:99939	32/115 (28%)
brd2a	NP_571275.2	Bromo_Brdt_I_like	72..178	CDD:99929
		Bromo_Brdt_II_like	383..484	CDD:99930	31/109 (28%)
		BET	676..738	CDD:293640
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810