Protein Alignment Brd8 and Brd8

DIOPT Version :10

• Sequence 1: NP_651685.2
• Gene: Brd8 / 43460
• FlyBaseID: FBgn0039654
• Length: 872
• Species: Drosophila melanogaster
• Sequence 2: XP_063133293.1
• Gene: Brd8 / 291691
• RGDID: 1307003
• Length: 1206
• Species: Rattus norvegicus
• Alignment Length: 1029
• Identity: 250/1029 - (24%)
• Similarity: 403/1029 - (39%)
• Gaps: 286/1029 - (27%)

  Fly     1 MSAGVQERLQLSRMPLDTWSKREQLILASAVSCSGDQNWITVSRTLKTICGNGSSNRPADWFSQK 65
            |:.|..:...||..|.:.||.||:|.|||:|..||||||::|||.:|.....|   ||.||||||
  Rat     1 MATGTGKHKLLSTGPTEPWSIREKLCLASSVMRSGDQNWVSVSRAIKPFAEPG---RPPDWFSQK 62

  Fly    66 NCAMQYGNLLESVEATKRKKRSSESSAGVSSPATVETPTELLLRRLTEERQAEIKAQMRQDQETY 130
            :||.||..|||:.|..|||:.....        .|||..::::|:||.||..|:|..:::.||.|
  Rat    63 HCASQYSELLETTETPKRKRGEKGE--------VVETVEDVIVRKLTAERVEELKKVIKETQERY 119

  Fly   131 RRIQREIESLQSDAVTEQELQDMWLEIEKEQEARRIEEMKLENRMREREQRKKDLASNWRNSSLA 195
            ||::|:.|.:|:..: :..|.::..:|..::        |||....|.:::..|.|...|.   |
  Rat   120 RRLKRDAELIQAGHM-DSRLDELCSDIAMKK--------KLEEEEAEVKRKATDAAYQARQ---A 172

  Fly   196 VKRSNQAADTTSVDMDVEDINTSGN---------------------------------------- 220
            ||...:...|..|...::..:..|:
  Rat   173 VKTPPRRLPTVMVRSPIDSASPGGDYPLGDLTPTTMEEATSGVTPGTLPSTPVTSFPGIPDTLPP 237

  Fly   221 ----------------------GKQQT-GPSPLLTSLLKS----PTG----NAPATPTP------ 248
                                  |::.| .|||||:.|||.    ||.    |....|.|
  Rat   238 GSAPLEAPMTPVTDDSPQKKMLGQKATPPPSPLLSELLKKGSLLPTSPRLVNESEMPVPSGHLSS 302

  Fly   249 -------GGAAPAAGGTGSVARAT-----------APTITSLLTSGPS---------SAVANQPV 286
                   ||..|...| |.:..||           |||::.||.:||:         :.||::|.
  Rat   303 TGVLLEVGGVLPMIHG-GDIQPATSAVAASPAASGAPTLSRLLEAGPTQFSTPLPSFTTVASEPP 366

  Fly   287 ITMKSP-----TDAAFMSRP-ITGPPASEASTTPTLERSPSQAAP-------------------- 325
            :.:..|     :.|..:..| :..|.::.|.:||......||..|
  Rat   367 VKLVPPPVESVSQATIVMMPALPAPSSAPAVSTPESVAPVSQPEPCVPLEAVGDPQTVTVSMDSS 431

  Fly   326 TLSMLLEKNMAAAKANESGSLVKPEGSGNQEQGVDEATSSAAGTADSDEADPNEAQLLEVFKNID 390
            .:||::  |....:...||....|.||         ...|..|..|.|.|:..:..:....:.:|
  Rat   432 EISMII--NSIKEECFRSGVAEAPGGS---------KAPSIDGKEDLDLAEKMDIAVSYTGEELD 485

  Fly   391 -QIIDDIDIDMASVIDDEILKNVDDVVASPSNDKAEVIDFEDKLDALKREQSKSSPAS------- 447
             :.:.||    .::|:|::            :|..||:|......||...:....|.|
  Rat   486 FETVGDI----IAIIEDKV------------DDHPEVLDVAAVEAALSFCEENDDPQSLPGPWEH 534

  Fly   448 ------DKPKSVELVIGSSDDSNDNIPLAA---VASQESKDRGQSGGESTRGTEDAESEPLTSEV 503
                  |||                :||.|   ...||..|           .|::|::.:...|
  Rat   535 PIQQERDKP----------------VPLPAPEMTVKQERLD-----------FEESETKGIHELV 572

  Fly   504 AVEEIGETITIIST-------SSEDTAGSPPTKMEEDGATDSLPKKEDAAEDKSEQ-ESSSQGQ- 559
            .:.:.|..|.:..|       .:|..||.        |...||...|..::|..|: .||:.|:
  Rat   573 DIRDSGVEIKVEPTEPEPGMSGAEIVAGV--------GPVPSLEPPELRSQDLDEEPRSSAAGEM 629

  Fly   560 NKAGGSTDEPE-----LIDHQATREAQSKSGKDTAGKPVTMQEKTTTQSAPVPVDLHDTDEESSS 619
            .:|.||:.:.|     .:..:|:.|  |.........|:....:..||.   ..::.|:.:|.|.
  Rat   630 GEADGSSGKGEERPLPAVKTEASPE--SMLSPSHGSNPIEDPLEAETQH---KFEMSDSLKEESG 689

  Fly   620 LTDSSKHDDHPRSAKAKPPALKLA-LDDSKSELELSGTPQPPSAPARTPLLRKLPHRDRSESPMV 683
            ....|:..|.|...:.:....:.| |::.|.|.:..|               .|...| :|.|:.
  Rat   690 TIFGSQIKDAPGEEEEEDGVSEAASLEEPKEEDQGEG---------------YLSEMD-NEPPVS 738

  Fly   684 DDDATTASDHSTARSTRRRCSSTPVIDSIPNSPASSEH---TDDRRETRAAS--KKLFLSIYAML 743
            :.|...:..::|.:       |..:.||||:|||||:.   ::|:...:|..  ||..:.::...
  Rat   739 ESDDGFSIHNATLQ-------SHTLGDSIPSSPASSQFSVCSEDQEAIQAQKIWKKAIMLVWRAA 796

  Fly   744 LDSKHAAPFKRPFHDEHAQRHADLCLRPMDFPTIKRNIDSGFIRSLSELHRDVLLMAHN-VLVAY 807
            .:.::|..|.:|..|:.|..:..:..||||..|||:||::|.|||.:|..||::||..| |:...
  Rat   797 ANHRYANVFLQPVTDDIAPGYHSIVQRPMDLSTIKKNIENGLIRSTAEFQRDIMLMFQNAVMYNS 861

  Fly   808 KPHTAQHKTARLFVQDCQAIKEF--SQL--PDVQAGITATPVSNTGSLRADKSS 857
            ..|...|....:.....:.|::|  :||  ...::||:|..:....|.|...:|
  Rat   862 SDHDVYHMAVEMQRDVLEQIQQFLATQLIMQTSESGISAKSLRGRDSTRKQDAS 915

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Brd8	NP_651685.2	PTZ00108	<111..367	CDD:240271	80/385 (21%)
		PHA03307	403..>708	CDD:223039	65/335 (19%)
		Bromo_brd8_like	729..833	CDD:99939	32/108 (30%)
Brd8	XP_063133293.1	None