DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Brd8 and C29F9.5

DIOPT Version :9

Sequence 1:	NP_651685.2	Gene:	Brd8 / 43460	FlyBaseID:	FBgn0039654	Length:	872	Species:	Drosophila melanogaster
Sequence 2:	NP_001355379.1	Gene:	C29F9.5 / 183022	WormBaseID:	WBGene00016220	Length:	261	Species:	Caenorhabditis elegans

Alignment Length:	248	Identity:	53/248 - (21%)
Similarity:	94/248 - (37%)	Gaps:	52/248 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SAGVQERLQLSRMPLDTWSKREQLILASAVSCSGDQNWITVSRTLKTICGNGSSNRPADWFSQKN 66
            |..||::.::|...::|...|:..:|..|..|        |.|.:| |......|.||   ....
Worm    22 SDNVQQQPRVSTATMNTLISRQLGLLLHAHEC--------VRRDIK-IREAAEKNEPA---PHAM 74

  Fly    67 CAMQYGNLLESV--EATKRKKRSSESSAGVSSPATV----------ETPT-ELLLRRLTEERQAE 118
            |.:|...:::.|  ..|..|:....:|...:|..|:          |.|. :.::.:.|...|..
Worm    75 CKIQDCVIMKEVLKHMTSCKEGPKCNSVHCASSRTILSHWKKCFNEECPVCKPIIEQRTAPPQDT 139

  Fly   119 IKAQMRQ---DQ-------ETYR-----RIQREIESLQSDAVTEQELQDMWLEIEKEQE------ 162
            ..|:.::   ||       :|||     :|.:.|.|........:...|.|.|..:..|
Worm   140 TPAEPKKPEHDQIWHLEVPKTYRSELIEKIYKGIMSNVKPGTLSEAQMDTWKEYSRSAELQIFDT 204

  Fly   163 ARRIE---EMKLENRMREREQRKKDLASNWRNSSLAVKRSNQAADT---TSVD 209
            |:::|   .|..|...|.:|...:...:..::.|...::.::|.|.   ||.|
Worm   205 AQKLEAYYHMAREKVCRYQEGFPRRQKTEEKDESDGSEKEDEADDRLEGTSTD 257

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Brd8	NP_651685.2	PaaSYMP	<105..188	CDD:291408	21/106 (20%)
		PHA03249	402..>582	CDD:223023
		Bromo_brd8_like	729..833	CDD:99939
C29F9.5	NP_001355379.1	ZnF_TAZ	40..128	CDD:214717	21/99 (21%)
C29F9.5	NP_001355379.1	KIX	153..223	CDD:280354	15/69 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900