DRSC/TRiP Functional Genomics Resources

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Protein Alignment Brd8 and Brd2

DIOPT Version :9

Sequence 1:NP_651685.2 Gene:Brd8 / 43460 FlyBaseID:FBgn0039654 Length:872 Species:Drosophila melanogaster
Sequence 2:NP_001191902.1 Gene:Brd2 / 14312 MGIID:99495 Length:798 Species:Mus musculus


Alignment Length:362 Identity:90/362 - (24%)
Similarity:127/362 - (35%) Gaps:92/362 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly   559 QNKAGGSTDEPELI------DHQATREAQSKSGKDTAGKPVTMQEKTT-----TQSAPVPVDLHD 612
            |..|....:|.||:      .|:...:..:..|..|:...|......:     |....:|..:.:
Mouse   174 QKVASMPQEEQELVVTIPKNSHKKGAKLAALQGSITSAHQVPAVSSVSHTALYTPPPEIPTTVLN 238

  Fly   613 TDEES--SSLTDSSKHDDHP--RSAKAKPPALKLALDDSKSELELSGTPQP-----PSAPAR--- 665
            ....|  ||....|.|...|  .:..|.|||..||..........:.||.|     |.:||.   
Mouse   239 IPHPSVISSPLLKSLHSAGPPLLAVSAAPPAQPLAKKKGVKRKADTTTPTPTAILAPGSPASPPG 303

  Fly   666 --TPLLRKLPHRDRSESPMVDDDATTASDHSTARSTRRRCSSTPVIDSIPNSPASSEHTDDRRET 728
              .|...:||       ||                  ||.|..|:.....:.|       |.::.
Mouse   304 SLEPKAARLP-------PM------------------RRESGRPIKPPRKDLP-------DSQQQ 336

  Fly   729 RAASKKLFLS--------IYAMLLDSKHAA---PFKRP-------FHDEHAQRHADLCLRPMDFP 775
            ..:|||..||        |...||..||||   ||.:|       .||.|     |:...|||..
Mouse   337 HQSSKKGKLSEQLKHCNGILKELLSKKHAAYAWPFYKPVDASALGLHDYH-----DIIKHPMDLS 396

  Fly   776 TIKRNIDSGFIRSLSELHRDVLLMAHNVLVAYKPHTAQHKTARLFVQDCQAIKEF--SQLPD--V 836
            |:||.:::...|...|...||.||..|   .||.:...|....: .:..|.:.||  :::||  :
Mouse   397 TVKRKMENRDYRDAQEFAADVRLMFSN---CYKYNPPDHDVVAM-ARKLQDVFEFRYAKMPDEPL 457

  Fly   837 QAG----ITATPVSNTGSLRADKSSGSKARSGSRKSQ 869
            :.|    .||.|...|.|.....|..|.:.|.|.:.:
Mouse   458 EPGPLPVSTALPPGLTKSSSESSSEESSSESSSEEEE 494

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Brd8NP_651685.2 PaaSYMP <105..188 CDD:291408
PHA03249 402..>582 CDD:223023 6/28 (21%)
Bromo_brd8_like 729..833 CDD:99939 38/123 (31%)
Brd2NP_001191902.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..21
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 53..72
Bromo_Brdt_I_like 73..179 CDD:99929 2/4 (50%)
PHA03247 <215..332 CDD:223021 30/148 (20%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 267..348 27/112 (24%)
Bromo_Brdt_II_like 348..449 CDD:99930 33/109 (30%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 454..645 11/41 (27%)
Nuclear localization signal. /evidence=ECO:0000255 553..557
BET 639..701 CDD:407211
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 736..798
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5076
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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