DRSC/TRiP Functional Genomics Resources

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Protein Alignment Cisd2 and CISD1

DIOPT Version :9

Sequence 1:NP_651684.1 Gene:Cisd2 / 43459 FlyBaseID:FBgn0062442 Length:133 Species:Drosophila melanogaster
Sequence 2:NP_060934.1 Gene:CISD1 / 55847 HGNCID:30880 Length:108 Species:Homo sapiens


Alignment Length:99 Identity:42/99 - (42%)
Similarity:65/99 - (65%) Gaps:5/99 - (5%)


- Green bases have known domain annotations that are detailed below.


  Fly    35 DWLALIPPTVVVAGLGYTAYLAYCPAARASCAAKNSGRCNNHIRKNEPKVVDMIDVEDIAEKAAF 99
            :|:|.:......|.:||.||..:.....     :|....|.||:|:.||:|...|:||:.:||.:
Human    12 EWIAAVTIAAGTAAIGYLAYKRFYVKDH-----RNKAMINLHIQKDNPKIVHAFDMEDLGDKAVY 71

  Fly   100 CRCWKTKNWPYCDGSHGEHNKQTGDNVGPIVIKK 133
            ||||::|.:|:|||:|.:||::|||||||::|||
Human    72 CRCWRSKKFPFCDGAHTKHNEETGDNVGPLIIKK 105

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Cisd2NP_651684.1 MitoNEET_N 1..62 CDD:287613 7/26 (27%)
ZnF_CDGSH 83..121 CDD:197836 19/37 (51%)
CISD1NP_060934.1 MitoNEET_N <12..41 CDD:313801 7/33 (21%)
ZnF_CDGSH 55..93 CDD:197836 19/37 (51%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165155014
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3461
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1393750at2759
OrthoFinder 1 1.000 - - FOG0002260
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 1 0.900 - - OOG6_103419
Panther 1 1.100 - - LDO PTHR13680
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R4512
SonicParanoid 1 1.000 - - X1493
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 1 0.960 - -
User_Submission 00.000 Not matched by this tool.
109.740

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