DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyt-c1L and cyc1

DIOPT Version :9

Sequence 1:	NP_651683.1	Gene:	Cyt-c1L / 43457	FlyBaseID:	FBgn0039651	Length:	344	Species:	Drosophila melanogaster
Sequence 2:	NP_001032470.1	Gene:	cyc1 / 564379	ZFINID:	ZDB-GENE-031105-2	Length:	307	Species:	Danio rerio

Alignment Length:	301	Identity:	169/301 - (56%)
Similarity:	210/301 - (69%)	Gaps:	9/301 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 LAMSGIQRTSVRPRISF--PGRGSGFT----GNRKLLGALGAL-TGTAGLLIYALETSVDASSDC 72
            :..||..||.:....:|  |.....|.    |.:..|..:|.| ||.|||.: .|:.||.||...
Zfish     7 VVFSGTGRTLLNTSKAFHTPRASMSFASLPKGKKIALTTIGVLTTGGAGLAL-MLQQSVKASDLE 70

  Fly    73 VHPAHQHWNHKGLLSALDKESVRRGYTVYKEVCSSCHSLQYMAYRNLVGVCMTEAEAKAEAEAIT 137
            :||....|:|.|.||:||..||||||.|||:|||:|||::|:|:||||||..||.|.|..||.|.
Zfish    71 LHPPTYPWSHGGFLSSLDHASVRRGYQVYKQVCSACHSMEYLAFRNLVGVSHTEDEVKTLAEEIE 135

  Fly   138 VRDGPNEEGEYYERPGKLSDHFPSPYANEEAARSANNGSYPPDLSYIVSARKGGEDYVFSLLTGY 202
            |.|||::.||.:.|||||||:||.||||.||||:||||:.||||||||:||.|||||||||||||
Zfish   136 VVDGPDDNGEMFTRPGKLSDYFPKPYANPEAARAANNGALPPDLSYIVNARHGGEDYVFSLLTGY 200

  Fly   203 CDPPAGFALRDGLYFNPYFSGGAIAMGKVVDNEVVSFEDPNVPASAAQIAKDVCVFLKWTSEPET 267
            ||||||.:||:|||:||||.|.||.|...:.|||:.::| ..||:.:|:|||||.||:|.:|||.
Zfish   201 CDPPAGVSLREGLYYNPYFPGQAIGMAPPIYNEVLEYDD-GTPATMSQVAKDVCTFLRWAAEPEH 264

  Fly   268 DERRLLLIKVTLISTFLIGISYYIKRFKWSTLKSRKIFFIP 308
            |:|:.:.:||.|....||.:.|||||.|||.||||||.:.|
Zfish   265 DDRKRMGLKVLLGGALLIPLIYYIKRHKWSVLKSRKIAYRP 305

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyt-c1L	NP_651683.1	CYT1	73..300	CDD:225413	141/226 (62%)
Cyt-c1L	NP_651683.1	Cytochrom_C1	80..299	CDD:280350	139/218 (64%)
cyc1	NP_001032470.1	CYT1	66..297	CDD:225413	143/231 (62%)
cyc1	NP_001032470.1	Cytochrom_C1	78..296	CDD:280350	139/218 (64%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170590047
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2857
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	370	1.000	Inparanoid score	I2087
OMA	1	1.010	-	-		QHG54185
OrthoDB	1	1.010	-	-		D439021at33208
OrthoFinder	1	1.000	-	-		FOG0003553
OrthoInspector	1	1.000	-	-		otm24321
orthoMCL	1	0.900	-	-		OOG6_102032
Panther	1	1.100	-	-	O	PTHR10266
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2430
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	14	13.770