DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyt-c1L and Cyc1

DIOPT Version :9

Sequence 1:	NP_651683.1	Gene:	Cyt-c1L / 43457	FlyBaseID:	FBgn0039651	Length:	344	Species:	Drosophila melanogaster
Sequence 2:	NP_001264123.1	Gene:	Cyc1 / 300047	RGDID:	1306597	Length:	326	Species:	Rattus norvegicus

Alignment Length:	293	Identity:	162/293 - (55%)
Similarity:	208/293 - (70%)	Gaps:	12/293 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 RPR---------ISFPGRGSGFTGNRKLLGALGAL-TGTAGLLIYALETSVDASSDCVHPAHQHW 80
            |||         :|...:.....|.:.:|.|||.| .|.|||.: ||.::|.||...:||....|
  Rat    34 RPRHLPLRTPQAVSLSSKSGPSRGRKVMLSALGMLAAGGAGLAV-ALHSAVSASDLELHPPSYPW 97

  Fly    81 NHKGLLSALDKESVRRGYTVYKEVCSSCHSLQYMAYRNLVGVCMTEAEAKAEAEAITVRDGPNEE 145
            :|:||||:||..|:|||:.|||:|||||||:.|:|||:|||||.||.||||.||.:.|:|||||:
  Rat    98 SHRGLLSSLDHTSIRRGFQVYKQVCSSCHSMDYVAYRHLVGVCYTEEEAKALAEEVEVQDGPNED 162

  Fly   146 GEYYERPGKLSDHFPSPYANEEAARSANNGSYPPDLSYIVSARKGGEDYVFSLLTGYCDPPAGFA 210
            |..:.|||||||:||.||.|.||||:||||:.||||||||.||.||||||||||||||:||.|.:
  Rat   163 GNMFMRPGKLSDYFPKPYPNPEAARAANNGALPPDLSYIVRARHGGEDYVFSLLTGYCEPPTGVS 227

  Fly   211 LRDGLYFNPYFSGGAIAMGKVVDNEVVSFEDPNVPASAAQIAKDVCVFLKWTSEPETDERRLLLI 275
            ||:||||||||.|.||.|...:..||:.::| ..||:.:|:||||..||:|.||||.|.|:.:.:
  Rat   228 LREGLYFNPYFPGQAIGMAPPIYTEVLEYDD-GTPATMSQVAKDVATFLRWASEPEHDHRKRMGL 291

  Fly   276 KVTLISTFLIGISYYIKRFKWSTLKSRKIFFIP 308
            |:.|:...|:.::|.:||.|||.|||||:.:.|
  Rat   292 KMLLMMGLLLPLTYAMKRHKWSVLKSRKLAYRP 324

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyt-c1L	NP_651683.1	CYT1	73..300	CDD:225413	137/226 (61%)
Cyt-c1L	NP_651683.1	Cytochrom_C1	80..299	CDD:280350	135/218 (62%)
Cyc1	NP_001264123.1	CYT1	85..288	CDD:225413	130/203 (64%)
Cyc1	NP_001264123.1	Cytochrom_C1	97..315	CDD:280350	135/218 (62%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166348891
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2857
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	371	1.000	Inparanoid score	I2059
OMA	1	1.010	-	-		QHG54185
OrthoDB	1	1.010	-	-		D439021at33208
OrthoFinder	1	1.000	-	-		FOG0003553
OrthoInspector	1	1.000	-	-		otm45968
orthoMCL	1	0.900	-	-		OOG6_102032
Panther	1	1.100	-	-	O	PTHR10266
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2430
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.770