DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mesh1 and ZK909.3

DIOPT Version :9

Sequence 1:	NP_651682.1	Gene:	Mesh1 / 43456	FlyBaseID:	FBgn0039650	Length:	179	Species:	Drosophila melanogaster
Sequence 2:	NP_493608.2	Gene:	ZK909.3 / 191461	WormBaseID:	WBGene00014148	Length:	229	Species:	Caenorhabditis elegans

Alignment Length:	166	Identity:	81/166 - (48%)
Similarity:	117/166 - (70%)	Gaps:	1/166 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 MECLQYAAFKHRQQRRKDPQETPYVNHVINVSTILSVEACITDEGVLMAALLHDVVEDTDASFED 74
            ::...:||.:||.|:||| ..|||:||.|.|..||:.||.:.|...|.||:||||||||..:.|:
Worm    62 LKATDFAARRHRHQKRKD-NATPYINHPIGVMYILTNEAKVYDPVTLAAAVLHDVVEDTKTTPEE 125

  Fly    75 VEKLFGPDVCGLVREVTDDKSLEKQERKRLQIENAAKSSCRAKLIKLADKLDNLRDLQVNTPTGW 139
            :::.||.:|..:|:|.||||:|.|.|||:|||||..|.|.:|||:.|||||.|||||:...|.||
Worm   126 IQQEFGNEVFQVVKECTDDKNLAKAERKKLQIENYGKHSHQAKLVHLADKLYNLRDLERKAPIGW 190

  Fly   140 TQERRDQYFVWAKKVVDNLRGTNANLELKLDEIFRQ 175
            .::|.::||.|:::|:..::|||.:||..||::..:
Worm   191 DKKRVNEYFKWSREVIGEMKGTNESLEYALDDVINR 226

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mesh1	NP_651682.1	SpoT	13..>147	CDD:223394	70/133 (53%)
Mesh1	NP_651682.1	HD_4	13..136	CDD:290067	66/122 (54%)
ZK909.3	NP_493608.2	SpoT	61..>204	CDD:223394	73/142 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160165446
Domainoid	1	1.000	123	1.000	Domainoid score	I3464
eggNOG	1	0.900	-	-		E1_COG0317
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H12279
Inparanoid	1	1.050	163	1.000	Inparanoid score	I2830
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG63160
OrthoDB	1	1.010	-	-		D1372331at2759
OrthoFinder	1	1.000	-	-		FOG0002754
OrthoInspector	1	1.000	-	-		oto18626
orthoMCL	1	0.900	-	-		OOG6_101946
Panther	1	1.100	-	-	LDO	PTHR46246
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3518
SonicParanoid	1	1.000	-	-		X4722
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	15	14.840