Protein Alignment CG11898 and abcc6a

DIOPT Version :10

• Sequence 1: NP_651679.2
• Gene: CG11898 / 43451
• FlyBaseID: FBgn0039645
• Length: 1320
• Species: Drosophila melanogaster
• Sequence 2: XP_009300481.1
• Gene: abcc6a / 566555
• ZFINID: ZDB-GENE-050517-18
• Length: 1507
• Species: Danio rerio
• Alignment Length: 1395
• Identity: 470/1395 - (33%)
• Similarity: 699/1395 - (50%)
• Gaps: 202/1395 - (14%)

  Fly     3 AVHEQRQPNPVTKANFFSKWFFIWTREILVKGLQRNLDPSDLYETEPSLESTQVSSFLLGHWEQE 67
            |||  :...||..|:|.||..|.|...::.||.:..|...||:    ||.....|..::...|:|
Zfish   198 AVH--KNACPVQDASFLSKILFWWFSGLIFKGYRSPLQAEDLW----SLREEDTSERIISDLEEE 256

  Fly    68 --LKRSK------------------PN-----------------VLRMIFKAYGWSFVPAS---I 92
              .||:|                  |:                 :||.:.:::|..|:..:   |
Zfish   257 WTAKRTKLQQQENHMSTSAALGSRLPDQAQLLRKIQKEQSSGFCLLRTLARSFGPYFLTGTLCLI 321

  Fly    93 VYSIMAIAVHTTQPLMLGGLVSFFSESTGKITKHSAYLYAMGVVLCSLISGLFFHPFMKYLFRVG 157
            |:.:...:|    |.:|..|:.|..:....:.|  .|.||..:.|.|.:..:|.|.:....|.||
Zfish   322 VHDVFMFSV----PQVLSLLLGFMKDEDTPLWK--GYFYATLMFLLSCLQSVFNHQYTYTCFTVG 380

  Fly   158 SRVRLACAGLVYRKFLRVSVAADNSGVSGYAISLMATDLPTFNESFYCFHELWRGPLEGVVFVYI 222
            .||:.|..||||||.|.::.:|..:...|..::|::.|.....:....|:.:|..|:|..:.::.
Zfish   381 MRVKTAVMGLVYRKSLVMNSSARRTCTVGEIVNLVSADTQKLMDFVVYFNAVWLAPIEVTLCLFF 445

  Fly   223 IYQLIGWPAVVGLGTIVAFIPLQAWAARAIARYKRSSADVGDERVKLMNEIIAAMQLIKMYAWEK 287
            ::|.:|..|:.|:.|::...||..:.||..::.:.......|.||||||||:..::::|.|||||
Zfish   446 LWQHLGPSALAGIATVIFIFPLNGFIARKRSKLQEIQMKYMDGRVKLMNEILNGIKILKFYAWEK 510

  Fly   288 SFAKLIGKVRKEEMDSIRGSTYIYA-GLQCTGMISKLSLFLSLVTYVFTGD--IVTSQKVFIVAS 349
            :|.:.:...|::|:.:::.|..:|: .|......|.|..|.....||...|  ::.:||:|:..:
Zfish   511 AFLEQVLGYREKELKTLKKSQILYSVSLASFNSSSFLIAFAMFGVYVLIDDKNVLDAQKIFVSMA 575

  Fly   350 YYDHLNDSLLHSWPLAINMWVETFVVANRVKDFLFQHE-NPADGGVHNFKEAEDNPEHGNFFGRT 413
            ..:.|. :.|...|.|::..::..|...|:..||.|.| .|            ||....:|
Zfish   576 LINILK-TPLSQLPFAMSTTMQALVSLKRLGKFLCQDELKP------------DNVARESF---- 623

  Fly   414 HKPKAEVKSITVHKLSASWDQKKQEKRHRHIEDVSFQAQDQQFVGIVGTVGAGKSTLLQVILGEL 478
               |::|..:.....:.||.:.......|    :|.:......|.:||.||:|||:||..:|||.
Zfish   624 ---KSDVDGVVFDNGTFSWSKDGPPCLKR----ISVKVPCGSLVAVVGHVGSGKSSLLSAMLGET 681

  Fly   479 DIISGSVEVNGVLSYAPQEPWLLRGSLRDNILFTEPYDEQRYLEVLRVCHLDRDVEQLPLGDSTR 543
            :..||:|.|.|.::|.||:.|:...||:|||||.....|..|..||..|.|..|::.||.||:|.
Zfish   682 EKRSGTVSVKGSIAYVPQQAWIQNASLQDNILFGREKKESWYQRVLEACALLPDLDNLPAGDATE 746

  Fly   544 VGEGGASLSGGQKARVSLARAVYRKADIYLLDDPLSAVDSHVSKMLLDRCLNE--FLSKKIRILV 606
            :||.|.:||||||.|||||||||||.|:|||||||||||:||.:.:.::.:..  .|..|.|:||
Zfish   747 IGEKGLNLSGGQKQRVSLARAVYRKGDVYLLDDPLSAVDAHVGQHIFNKVIGPKGILRDKTRVLV 811

  Fly   607 THRVQLLRHVDHLVLLEGGRISVQGHYDAL-------------------------------KKLI 640
            ||.:..|...|.:::|..|.||.:|.|..|                               :|.:
Zfish   812 THGMSFLPQADLILVLVDGEISERGSYQELLNRNGAFADFIHTFANSERKECFSEALQRGSRKSV 876

  Fly   641 RFR----MSVANDVEVAKLRAMRTDSVYEEPEPRKSLSQEEHMDRHEIEQQFKEQQQIGSVKLQT 701
            |..    |..:.|:...:|....|:|:..||.|.   |.|:|:.....:....::.:||.|||:.
Zfish   877 RLSVTDYMPFSRDLSQEQLIGGDTNSIAIEPLPD---SDEDHIPEDLGKLTKVDKARIGRVKLEM 938

  Fly   702 YKEYFKVLGHPLVVVLILLMFVVARSSEATMDIFLSKWATWEETEPNQHEPIPEYHRTRLRMMIL 766
            |.|||:.:|.||::.::.| :...:::..:.:.:||.||..           |..:.|:|.
Zfish   939 YIEYFRTIGLPLIISIVFL-YAFQQAASLSNNYWLSLWADQ-----------PVINGTQLN---- 987

  Fly   767 YTFLILCTLIFYVLRTFGF------FMMTLRISL-------RIHDQLFQGVIRAFMHFFTLATSG 818
                  ..|...|....||      |..|:.|||       .:|..|...|:.:.|.||....||
Zfish   988 ------TDLKLGVYGALGFAQGISIFGTTVAISLGCIIASRHLHLDLLNNVLHSPMSFFESTPSG 1046

  Fly   819 RILNRFSSDVLAIDVNLPQA--MMDSIEFAVNALAVLAVVSTANIWLLIPATVVVAL----LYG- 876
            .:||||:.::.|||..:|..  ||.|..|.:..:.::.:::|       |...|:.|    |||
Zfish  1047 NLLNRFAKEIDAIDNMIPDGLKMMLSYFFKLTEVCIIVLMAT-------PFAAVIILPMVFLYGF 1104

  Fly   877 CRCLYIGASRSLKRIETISRSPIYSHTNATFKGLATIRALNGTKYMERDFHYYQNENTSALYLHV 941
            .:..|:..|..|:|:|::||||||:|.|.|.:|.:.|||.|.........::..:.|.:|.:...
Zfish  1105 IQSFYVATSCQLRRLESVSRSPIYTHLNETVQGASVIRAFNEQSRFIMGANHKVDHNQTAYFPRF 1169

  Fly   942 SINRAFAFWTDLICVLYILAVTFSFL----------LFDKHRGYYS-GDVGLAITQSMKLVLMCQ 995
            ...|    |         |.|...||          |....:|..| |.||||::.|:::.....
Zfish  1170 IATR----W---------LGVNLEFLGNGIVLAASILSVMAKGTLSPGMVGLAVSHSLQVTGFLS 1221

  Fly   996 AGMRQTVELENMMTSVERVMEYVNIPSEPAYETEESVNLPKHWPSGGQLDFRDLRLRYSNHGPYI 1060
            ..:|...::||.:.|||||.||.:.|.|.|:..|.| :||..||..|.::|:|..|:|.......
Zfish  1222 WIVRSWTDVENNIVSVERVKEYADTPKEAAWSIEGS-SLPPSWPQTGTIEFQDYGLQYRKGLELA 1285

  Fly  1061 LKGLTFTIRGEEKIGIVGHTAAGKSSIVHALFR-LAHINGHISIDGFETSQLGLHDLRRRISIIP 1124
            |||::..|...|||||||.|.|||||:...:|| |....|.|.|||...:::||||||.||:|||
Zfish  1286 LKGISVHIHEREKIGIVGRTGAGKSSLALGIFRILEAAKGEIYIDGINIAEIGLHDLRSRITIIP 1350

  Fly  1125 QDPVLFSGSLRFNLDPFEEKTDEELWLALEAVKLKEFVSNLKDGINCRLHDC---GANFSMGQRQ 1186
            |||||||||||.|||||...:|||:|.|||...||.|||.|.|.:|   |:|   |.|.|:||||
Zfish  1351 QDPVLFSGSLRMNLDPFNAYSDEEVWNALELAHLKNFVSELPDKLN---HECSEGGENLSLGQRQ 1412

  Fly  1187 LVCLARALLRQNKILIMDEATANVDPETDNLIQEAIHTKFAHCTVLTIAHRLHTVMDNDRVMVVD 1251
            ||||||||||:.|:|::|||||.:|.|||.|||..|.::|..|.||||||||:|:||..:|:|:|
Zfish  1413 LVCLARALLRKTKVLVLDEATAALDLETDTLIQSTIRSQFEDCAVLTIAHRLNTIMDYTKVIVMD 1477

  Fly  1252 MGRVVELGHPHELLHNRHGYLHRFVEKTGV 1281
            .|.|||:..|..|:..| |..:....:.|:
Zfish  1478 KGHVVEMDSPSNLIAKR-GQFYYMCREAGL 1506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11898	NP_651679.2	MRP_assoc_pro	2..1268	CDD:188098	467/1380 (34%)
abcc6a	XP_009300481.1	MRP_assoc_pro	5..1506	CDD:188098	469/1393 (34%)