Protein Alignment CG11898 and Mrp4

DIOPT Version :10

• Sequence 1: NP_651679.2
• Gene: CG11898 / 43451
• FlyBaseID: FBgn0039645
• Length: 1320
• Species: Drosophila melanogaster
• Sequence 2: NP_650086.2
• Gene: Mrp4 / 41387
• FlyBaseID: FBgn0263316
• Length: 1316
• Species: Drosophila melanogaster
• Alignment Length: 1333
• Identity: 514/1333 - (38%)
• Similarity: 762/1333 - (57%)
• Gaps: 85/1333 - (6%)

  Fly    11 NPVTKANFFSKWFFIWTREILVKGLQRNLDPSDLYETEPSLESTQVSSFLLGHW-EQELKRSKPN 74
            ||..:::..|...|.:...:|.||.::.|:..|||......:|..:...|...| ||..|...|.
  Fly    12 NPRERSSPLSSLMFCFALPVLFKGRKKTLEQKDLYRALKEHKSDSLGDRLCAAWDEQVAKNETPR 76

  Fly    75 VLRMIFKAYGWSFVPASIVYSIMAIAVHTTQPLMLGGLVSFFSESTGKITKHSAYLYAMGVVLCS 139
            :.|.:.|.:|:......:...........|||:.|.|::::|:.:....:|  |.|:|.|::..|
  Fly    77 LGRALTKVFGFHLFITGVFLLAQEFLTKVTQPICLIGVMAYFAGNDPDRSK--AQLWAAGLIAGS 139

  Fly   140 LISGLFFHPFMKYLFRVGSRVRLACAGLVYRKFLRVSVAADNSGVSGYAISLMATDLPTFNESFY 204
            :.|....||:|..|..:|.::|:|.:.|:|||.||:|..|......|..::|::.|:..|:....
  Fly   140 VFSVCIGHPYMLGLLHLGMKMRIALSSLIYRKALRLSRTALGDTTVGQVVNLLSNDVGRFDLVLI 204

  Fly   205 CFHELWRGPLEGVVFVYIIYQLIGWPAVVGLGTIVAFIPLQAWAARAIARYKRSSADVGDERVKL 269
            ..|.||..|||.:...|::|..||..::.|:..::.|:|.|::..:..:..:..:|...||||::
  Fly   205 NVHYLWIAPLELIAVTYLMYLEIGISSMFGVAIMLLFLPFQSYLGKRTSVLRLRTALRTDERVRM 269

  Fly   270 MNEIIAAMQLIKMYAWEKSFAKLIGKVRKEEMDSIRGSTYIYAGLQCTGMISKLSLFL------- 327
            |||||:.:|:||||||||.|.|::...|..||..|:...||      .|::...::||
  Fly   270 MNEIISGIQVIKMYAWEKPFGKVVEMTRFNEMLCIKQVNYI------RGILISFAMFLSRIFTSS 328

  Fly   328 SLVTYVFTGDIVTSQKVFIVASYYDHLNDSLLHSWPLAINMWVETFVVANRVKDFLFQHENPA-- 390
            ||:.:|..|:|:.::|.|.|.:||:.|..|:...:|..|:.:.|..|...|::.|:.:.|...
  Fly   329 SLIAFVLLGNILNAEKAFFVTAYYNILRRSVTMFFPQGISEFAELLVSVRRLEAFMHRPETKVRD 393

  Fly   391 DGGVHNFKEAEDNPEHGNFFGRTHKPKAE---VKSITVHKLSASWDQKKQEKRHRHIEDVSFQAQ 452
            ...|.|..:..::| :|:      .||..   ...|...:..|.|:....|..   :||::.|..
  Fly   394 KSKVKNANQKAESP-NGD------SPKGNGIPENLIEFSQFQARWESHSLEPT---LEDINLQLG 448

  Fly   453 DQQFVGIVGTVGAGKSTLLQVILGELDIISGSVEVNGVLSYAPQEPWLLRGSLRDNILFTEPYDE 517
            .::.|.::|.||||||:|:|.|||||...||::.:||..|||.|||||..|::|.||||...:|:
  Fly   449 RRKLVAVIGPVGAGKSSLIQAILGELPGESGTLRINGSYSYAAQEPWLFTGTVRQNILFGLDWDK 513

  Fly   518 QRYLEVLRVCHLDRDVEQLPLGDSTRVGEGGASLSGGQKARVSLARAVYRKADIYLLDDPLSAVD 582
            .||..|::.|.|:||.|.||.||.|.|||.|||||||||||:||||||||:||||||||||||||
  Fly   514 HRYRTVVKKCALERDFELLPFGDKTIVGERGASLSGGQKARISLARAVYRRADIYLLDDPLSAVD 578

  Fly   583 SHVSKMLLDRCLNEFLSKKIRILVTHRVQLLRHVDHLVLLEGGRISVQGHYDALKK-------LI 640
            :||.:.|.|:|:..:|..::.|||||::|.|...|.:|:::.||||..|.|.::|:       |:
  Fly   579 THVGRHLFDQCMRGYLRSELVILVTHQLQFLEQADLIVIMDKGRISAMGTYSSMKRSGLDFAQLL 643

  Fly   641 RFRMSVANDVE--------------VAKLRAMRTDSVYEEPEPRK----SLSQEEHMDRHEIEQQ 687
            ......|.|::              |..|  .|..|...:|..|.    |||........|...|
  Fly   644 TAPNKDAEDLDEIDGAGGDGLDLLNVPSL--SRRGSKNSKPSTRNNSFTSLSSMAESMAQEASLQ 706

  Fly   688 FKEQQQIGSVKLQTYKEYFKVLGHPLVVVLILLMFVVARSSEATMDIFLSKWA-------TWEET 745
            .:|.:..|.:.|..||||........::..::.:.:..:...:..|.|||.|.       |...|
  Fly   707 MQETRVEGKIGLGLYKEYLTSGSSWFMIFFMVFLCLATQILCSAADYFLSYWVDKNVDGQTDINT 771

  Fly   746 EPNQHEPIPEYHRTRLRMMILYTFLILCTLIFYVLRTFGFFMMTLRISLRIHDQLFQGVIRAFMH 810
            :|..              |..:..|.:..::|.::||..|:.|.:|.|.::|:.::||:.||.|:
  Fly   772 DPQD--------------MYYFAALNVAVVVFTIVRTMLFYKMAMRSSTQLHNAMYQGITRAAMY 822

  Fly   811 FFTLATSGRILNRFSSDVLAIDVNLPQAMMDSIEFAVNALAVLAVVSTANIWLLIPATVVVALLY 875
            ||....|||||||||.|:..:|..||..|:|.::..:..|.::.|:...|.:.||....:..:.|
  Fly   823 FFNTNPSGRILNRFSKDLGQLDEVLPSVMLDVVQLFLTLLGIIVVICITNPYYLILTLALAIIFY 887

  Fly   876 GCRCLYIGASRSLKRIETISRSPIYSHTNATFKGLATIRALNGTKYMERDFHYYQNENTSALYLH 940
            ..|..|:..||.:||:|.::|||||||.:||..||.|||||...|.:..:|...|:.::|..|..
  Fly   888 YIREFYLKTSRDVKRLEAVARSPIYSHLSATITGLPTIRALGAQKELIAEFDNLQDLHSSGYYTF 952

  Fly   941 VSINRAFAFWTDLICVLYILAVTFSFLLFDKHRGYYSGDVGLAITQSMKLVLMCQAGMRQTVELE 1005
            ::.||||.::.|..|.|||:.:..::.:   :.....|:|||||||:|.:..|.|..|||:.|||
  Fly   953 LATNRAFGYYLDCFCTLYIVIIILNYFI---NPPQSPGEVGLAITQAMGMTGMVQWAMRQSAELE 1014

  Fly  1006 NMMTSVERVMEYVNIPSEPAYETEESVNLPKHWPSGGQLDFRDLRLRY--SNHGPYILKGLTFTI 1068
            |.||:||||:||..|..|..:::.|.......||..|::...||.|||  .....|:||.|.|.|
  Fly  1015 NTMTAVERVVEYDEIEPEGEFDSREGKKPSPSWPEKGEIIAEDLCLRYFPDPQAKYVLKALNFRI 1079

  Fly  1069 RGEEKIGIVGHTAAGKSSIVHALFRLAHINGHISIDGFETSQLGLHDLRRRISIIPQDPVLFSGS 1133
            |..||:||||.|.|||||:::|||||::..|.|:||..:|:.:||.|||.:||||||:|||||||
  Fly  1080 RPCEKVGIVGRTGAGKSSLINALFRLSYNEGIITIDERDTADMGLFDLRSKISIIPQEPVLFSGS 1144

  Fly  1134 LRFNLDPFEEKTDEELWLALEAVKLKEFVSNLKDGINCRLHDCGANFSMGQRQLVCLARALLRQN 1198
            :|:|||||||..|.:||.|||.||||..:|.|.:|:..::.:.|:|||:|||||||||||:||:|
  Fly  1145 MRYNLDPFEEYNDAKLWDALEEVKLKPLISELPNGLQSKISEGGSNFSVGQRQLVCLARAILREN 1209

  Fly  1199 KILIMDEATANVDPETDNLIQEAIHTKFAHCTVLTIAHRLHTVMDNDRVMVVDMGRVVELGHPHE 1263
            ::|:||||||||||:||.|||..|.:||..||||||||||:|:||:|||:|:|.|.:||.|.|:|
  Fly  1210 RVLVMDEATANVDPQTDALIQATIRSKFRDCTVLTIAHRLNTIMDSDRVLVMDAGHLVEFGSPYE 1274

  Fly  1264 LLHNRHGYL-HRFVEKTGVGTAQHLRHLAEQSY 1295
            ||.:....: |..|.:||..|...|..:||:::
  Fly  1275 LLTSSESKIFHGMVMETGQNTFDSLLKVAEKAH 1307

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11898	NP_651679.2	MRP_assoc_pro	2..1268	CDD:188098	506/1303 (39%)
Mrp4	NP_650086.2	MRP_assoc_pro	13..1292	CDD:188098	507/1315 (39%)