Protein Alignment CG11898 and abcc4

DIOPT Version :10

• Sequence 1: NP_651679.2
• Gene: CG11898 / 43451
• FlyBaseID: FBgn0039645
• Length: 1320
• Species: Drosophila melanogaster
• Sequence 2: NP_001007039.2
• Gene: abcc4 / 368620
• ZFINID: ZDB-GENE-030616-511
• Length: 1331
• Species: Danio rerio
• Alignment Length: 1339
• Identity: 480/1339 - (35%)
• Similarity: 766/1339 - (57%)
• Gaps: 77/1339 - (5%)

  Fly     1 MSAVHEQRQPNPVTKANFFSKWFFIWTREILVKGLQRNLDPSDLYETEPSLESTQVSSFLLGHWE 65
            |..:.:..:.||...||.||:.||.|...:...|.:|.|:..|::...|...|.::...|..:|:
Zfish     5 MEPIKKDAKSNPSASANLFSQIFFCWLNPLFSIGSKRRLEEDDMFNVLPEDRSKKLGEELQSYWD 69

  Fly    66 QELKRS-----KPNVLRMIFKAYGWSFVPASIVYSIMAIAVHTTQPLMLGGLVSFFSESTGKITK 125
            ||.:::     .|.:.:.|.:.| |.......|::::..::...||:.||.|:.:|..     .:
Zfish    70 QEKEKAAKELKTPKLTKAIIRCY-WKSYAVLGVFTLIEESIKVIQPVFLGKLIKYFEN-----YR 128

  Fly   126 H-------SAYLYAMGVVLCSLISGLFFHPFMKYLFRVGSRVRLACAGLVYRKFLRVSVAADNSG 183
            |       .||.||.||.|.:|...|..|.:..::.|.|.::|:|...::|||.|.:|.||....
Zfish   129 HDDMAALSEAYGYATGVCLSTLGLALLHHLYFYHVQRAGMKIRIAMCHMIYRKALCLSAAAMGQT 193

  Fly   184 VSGYAISLMATDLPTFNESFYCFHELWRGPLEGVVFVYIIYQLIGWPAVVGLGTIVAFIPLQAWA 248
            .:|..::|::.|:..|:|.....|.||.|||:....:.:::|.||...:.|:..:|..:|||...
Zfish   194 TTGQIVNLLSNDVNKFDELTIFLHFLWVGPLQAAAVIGLLWQEIGPSCLAGMAVLVFLMPLQTMF 258

  Fly   249 ARAIARYKRSSADVGDERVKLMNEIIAAMQLIKMYAWEKSFAKLIGKVRKEEMDSIRGSTYIYAG 313
            .:..::|:..:|.:.|.|::.|||:::.:::||||||||.||.|:..||::|:..|..|:|: .|
Zfish   259 GKLFSKYRSKTAALTDSRIRTMNEVVSGIRIIKMYAWEKPFAMLVNDVRRKEISKIMSSSYL-RG 322

  Fly   314 LQCTGMI--SKLSLFLSLVTYVFTGDIVTSQKVFIVASYYDHLNDSLLHSWPLAINMWVETFVVA 376
            |......  :|:.||::...||..|:.:::.:||:..|.|..:..::...:|.||....|:.:..
Zfish   323 LNMASFFTANKIILFVTFTVYVLVGNTMSASRVFVAVSLYSAVRLTVTLFFPAAIEKVSESAISI 387

  Fly   377 NRVKDFLFQHENPADGGVHNFKEAEDNPEHGNFFGRTHKPKAEVK----SITVHKLSASWDQKKQ 437
            .|:|.||...|                      ..:.|.|.::.:    |:.:..|...||:...
Zfish   388 RRIKKFLLLDE----------------------LVKNHLPLSQEEKKEPSVEMQDLICYWDKTLD 430

  Fly   438 EKRHRHIEDVSFQAQDQQFVGIVGTVGAGKSTLLQVILGELDIISGSVEVNGVLSYAPQEPWLLR 502
            ...   :::|.|..:..|.:.::|.||||||:||..:||||....|.::|.|.|:||.|:||:..
Zfish   431 APT---LQNVCFTVKPGQLLAVIGPVGAGKSSLLSTVLGELPAEKGVIKVKGELTYASQQPWVFP 492

  Fly   503 GSLRDNILFTEPYDEQRYLEVLRVCHLDRDVEQLPLGDSTRVGEGGASLSGGQKARVSLARAVYR 567
            |::|.||||.:....|||..|||.|.|.||:|.||.||.|.:|:.||:|||||||||:||||||:
Zfish   493 GTIRSNILFGKELQPQRYERVLRACALKRDMELLPDGDLTVIGDRGATLSGGQKARVNLARAVYQ 557

  Fly   568 KADIYLLDDPLSAVDSHVSKMLLDRCLNEFLSKKIRILVTHRVQLLRHVDHLVLLEGGRISVQGH 632
            .||||||||||||||:.||:.|.::|:...|..|.||||||::|.|:..:.:::|:.|.:..:|.
Zfish   558 DADIYLLDDPLSAVDAEVSRHLFEQCVCGILKDKPRILVTHQLQYLKAANQILVLKEGHMVARGS 622

  Fly   633 YDALKKL-IRFRMSVANDVE------------VAKLRAMRTDSVYEEPEPRKSLSQE-EHMDRHE 683
            |..|::. :.|...:..|.|            ..:.|.:..:||........|:..: :.:....
Zfish   623 YSELQQSGLDFTSLLKKDEEEESGSEKGEAPRSPRSRTVSQNSVRSHSSSVLSVKDDSDQLPAEP 687

  Fly   684 IEQQFKEQQQIGSVKLQTYKEYFKVLGHPLVVVLILLMFVVARSSEATMDIFLSKWATWEE---- 744
            :....:|.:..|::.::.|.:||:...:.:::||:||:.::|::.....|.:||.|||.:|
Zfish   688 VHTMAEELRSEGNIGIRMYWKYFRAGANVVMLVLLLLLNLLAQTFYILQDWWLSYWATEQEKLDH 752

  Fly   745 ----TEPNQHEPIPEYHRTRLRMMI-LYTFLILCTLIFYVLRTFGFFMMTLRISLRIHDQLFQGV 804
                |..|.........:..|...: :|..|...|::|..:|....|...:..:..:|:::|..:
Zfish   753 NTNNTNTNNTSAGNTTQQLDLNFYLGIYAGLTGATIVFGFMRCLIMFNALVSSAEMLHNRMFNSI 817

  Fly   805 IRAFMHFFTLATSGRILNRFSSDVLAIDVNLPQAMMDSIEFAVNALAVLAVVSTANIWLLIPATV 869
            :|..:.||.:...||||||||.|:..:|..||...:|.|:..:..:.|:||.|:...|:|||...
Zfish   818 LRTPVRFFDINPIGRILNRFSKDIGHLDSLLPWTFVDFIQVFLQIVGVIAVASSVIPWILIPVLP 882

  Fly   870 VVALLYGCRCLYIGASRSLKRIETISRSPIYSHTNATFKGLATIRALNGTKYMERDFHYYQNENT 934
            ::......|..::..||.:||||:.:|||::||.:::.:||.||||....:..::.|..:|:.::
Zfish   883 LLICFLFLRRYFLRTSRDVKRIESTTRSPVFSHLSSSLQGLWTIRAFKAEERFQQTFDAHQDLHS 947

  Fly   935 SALYLHVSINRAFAFWTDLICVLYILAVTFSFLLFDKHRGYYSGDVGLAITQSMKLVLMCQAGMR 999
            .|.:|.::.:|.||...|.:|.:::....|..||......  :||||||::.::.|:.|.|.|:|
Zfish   948 EAWFLFLTTSRWFAVRLDGMCSVFVTITAFGCLLLKDTMN--AGDVGLALSYAVTLMGMFQWGVR 1010

  Fly  1000 QTVELENMMTSVERVMEYVNIPSEPAYETEESVNLPKHWPSGGQLDFRDLRLRYSNHGPYILKGL 1064
            |:.|:||||||||||:||..:.||..:||::..:  ..||:.|.:.|..:...||:.||.:||.:
Zfish  1011 QSAEVENMMTSVERVVEYTELESEAPWETQKRPS--PDWPNRGLITFDRVNFSYSSDGPVVLKNI 1073

  Fly  1065 TFTIRGEEKIGIVGHTAAGKSSIVHALFRLAHINGHISIDGFETSQLGLHDLRRRISIIPQDPVL 1129
            :...|..||:||||.|.|||||::.|||||:...|.|.:||..||::||||||:::|||||||||
Zfish  1074 SAMFRPREKVGIVGRTGAGKSSLISALFRLSEPEGKILVDGVLTSEIGLHDLRQKMSIIPQDPVL 1138

  Fly  1130 FSGSLRFNLDPFEEKTDEELWLALEAVKLKEFVSNLKDGINCRLHDCGANFSMGQRQLVCLARAL 1194
            |:|::|.|||||.:.:|.:||.|||.|:||..|..|...:...|.:.|:|||:|||||||||||:
Zfish  1139 FTGTMRKNLDPFNQHSDHDLWKALEEVQLKAAVEELPGKLETELAESGSNFSVGQRQLVCLARAI 1203

  Fly  1195 LRQNKILIMDEATANVDPETDNLIQEAIHTKFAHCTVLTIAHRLHTVMDNDRVMVVDMGRVVELG 1259
            ||:|::||:|||||||||.||.|||:.|..||..||||||||||:|::|:||::|:|.||:.|..
Zfish  1204 LRKNRVLIIDEATANVDPRTDELIQKTIRDKFKECTVLTIAHRLNTIIDSDRILVLDAGRIHEYD 1268

  Fly  1260 HPHELLHNRHGYLHRFVEKTGVGTAQHLRHLAEQSYRKR 1298
            .||.||.|:.|..::.|::||...|..|...|:|:|..|
Zfish  1269 APHVLLQNQSGIFYKMVQQTGKAEATSLLQTAKQAYANR 1307

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11898	NP_651679.2	MRP_assoc_pro	2..1268	CDD:188098	468/1306 (36%)
abcc4	NP_001007039.2	MRP_assoc_pro	11..1289	CDD:188098	471/1313 (36%)