Protein Alignment CG11898 and abc4

DIOPT Version :10

• Sequence 1: NP_651679.2
• Gene: CG11898 / 43451
• FlyBaseID: FBgn0039645
• Length: 1320
• Species: Drosophila melanogaster
• Sequence 2: NP_594558.1
• Gene: abc4 / 2543059
• PomBaseID: SPAC30.04C
• Length: 1469
• Species: Schizosaccharomyces pombe
• Alignment Length: 1252
• Identity: 376/1252 - (30%)
• Similarity: 587/1252 - (46%)
• Gaps: 101/1252 - (8%)

  Fly    64 WEQELKRSK-PNVLRMIFKAYGWSFVPASIVYSIMAIAVHTTQPLMLGGLVSFFSESTGKITKHS 127
            |....:|.| |::...|.|.: |..:....|.|.|........|:.|..|:......:.......
pombe   272 WTYRFERMKTPSLFITIHKIF-WRQILGMGVSSFMVSVCQFLSPIALNRLLKHLESPSSSSVNPL 335

  Fly   128 AYLYAM--GVVLCSLISGLFFHPFMKYLFRVGSRVRLACAGLVYRKFLRVSVAADNSGVS--GYA 188
            .::..:  |..|.||.:..:.....:||    :|........:|.|.:|.....:.||.|  |.:
pombe   336 VWIVLLLTGPFLTSLFTQFYLFMSTRYL----ARSYTTLVQQIYNKVIRSRFVQNKSGDSKVGRS 396

  Fly   189 ISLMATDLPTFNESFYCFHELWRGPLEGVVFVYIIYQLIGWPAVVGLGTIVAF----IPLQAWAA 249
            .:|::||:....|.....|.:.|.|:|....:|::.:|:||.|.|||...|..    |.|....|
pombe   397 NNLISTDVDDIGEIREFIHIIVRAPVEIAGSIYLLQKLLGWSAYVGLALTVLTCSVPIVLGPLVA 461

  Fly   250 RAIARYKRSSADVGDERVKLMNEIIAAMQLIKMYAWEKSFAKLIGKVRKEEMDSIRGSTYIYAGL 314
            :...|..|::    |.|::||:|::.::::.|.:.||......:.:.|:.|::  |....:...:
pombe   462 KLTLRANRAT----DSRIELMSELLQSIRITKFFGWELPMLDRVKQRRQVELN--RTWKLLLMEI 520

  Fly   315 QCTGMISKLSLFLSLVTY-VFT---GDIVTSQKVFIVASYYDHLNDSLLHSW-PLAINMWVETFV 374
            ....::..|.:|....|: |||   |..:|....|...|.:..:....  || ...:...|:.||
pombe   521 CIQVLVESLPVFSMFATFVVFTTIMGQTITPSIAFTSISLFSFIRTQF--SWIAYLMRQIVQIFV 583

  Fly   375 VANRVKDFLFQHENPADGGVHNFKEAEDNPEHGNFFGRTHKPKAEVKSITVHKLSASWDQKKQEK 439
            ...||.|||    |..| .|......||..:...||                ..|.:| ......
pombe   584 SIGRVSDFL----NDPD-EVDPVNTIEDTSQEIGFF----------------NASLTW-VSNPSP 626

  Fly   440 RHRHIEDVSFQAQDQQFVGIVGTVGAGKSTLLQVILGELDIISGSVEV---NGVLSYAPQEPWLL 501
            ....:.|::......:...::|..|:|||:|:..:||||.:..||..:   .|| ||..|.|||.
pombe   627 GDFCLRDLNIVFPRNKLSIVIGPTGSGKSSLISALLGELSLNKGSYNLPRSKGV-SYVSQVPWLR 690

  Fly   502 RGSLRDNILFTEPYDEQRYLEVLRVCHLDRDVEQLPLGDSTRVGEGGASLSGGQKARVSLARAVY 566
            ..::||||||..||.|:||.:|::.|.|..|::.....|.|.:||.|.:||||||.|::||||||
pombe   691 NATIRDNILFDYPYIEERYKKVIQACGLLTDLQSFVASDLTEIGEKGVTLSGGQKQRIALARAVY 755

  Fly   567 RKADIYLLDDPLSAVDSHVSKMLLDRCL-NEFLSKKIRILVTHRVQL-LRHVDHLVLLEGGRISV 629
            ....|.|:||..||:|.|.|..:...|. :..:..:..|||||.|.| :.....:|.::.|  |.
pombe   756 SPTSIVLMDDVFSALDIHTSNWIYKHCFQSSLMENRTVILVTHNVHLFMDSAAFIVTVKNG--SA 818

  Fly   630 QGHYDALKKLIRFRMSVANDVEVA--KLRAMRTDSVYEEPEPRKSLSQEEHMDRHEIEQQFKEQQ 692
            ....|....|:......|:..|.|  .|.|:        |.|.: :...|..|..:.:...:||:
pombe   819 FPVTDKSSPLLFLAEQAASASEAAAPDLAAI--------PIPNE-VDDAEAADEKDGKLVEEEQR 874

  Fly   693 QIGSVKLQTYKEYFKVLGHPLVVVLILLMFVVARSSEATMDIFLSKWATWEETEPNQHEPIPEYH 757
            ..|.|.......|.|..|....|..:||.||..:::...:|::::.|.......|:.:..
pombe   875 VTGDVVFSEIFSYMKHFGSGFYVAAVLLFFVTTQATSILIDLWVAFWTNSSVNSPDVNNN----- 934

  Fly   758 RTRLRMMILYTFLILCTLIFYVLRTFGFFMMTLRISLRIHDQLFQGVIRAFMHFFTLATSGRILN 822
                :.:.:|..::|...:...|||..:.......|.::||.:.:.|...|..:|....:|||:|
pombe   935 ----KFLFVYGTMLLAYSLLDFLRTVSYDRGAWWASRKLHDSMLESVFGTFASWFDKTPTGRIVN 995

  Fly   823 RFSSDVLAIDVNLPQAMMDSIEFAVNALAVLAVVSTANIWLLIPATVVVALLYGCRCLYIGASRS 887
            ||:.|:.:||:||...:..||...::....:..||:|....:|||.:|....|....||..|...
pombe   996 RFAKDIRSIDMNLSGWLFFSINCFLSVAGGILSVSSAMPIFMIPAVIVCLAGYYFGLLYTRAQVG 1060

  Fly   888 LKRIETISRSPIYSHTNATFKGLATIRALN-----GTKYMERDFHYYQNENTSALYLHVSINRAF 947
            :||:.:|..|||:|....:..|::.|||.|     ...:.||..:..:.::||     .::||..
pombe  1061 VKRLISIYTSPIFSLLGESIVGVSVIRAFNRQTIFKQMFSERLDNLVRLQSTS-----YNLNRWV 1120

  Fly   948 AFWTDLICVLYILAVTFSFLLFDKHRGYYSGDVGLAITQSMKLVLMCQAGMRQTVELENMMTSVE 1012
            |..||.|..| :.|:.....|..|...  .|.||.::.|::.........:|....|:..|.|.|
pombe  1121 AVRTDGISGL-VGAIAGLIALLQKDLS--PGVVGFSLNQAVIFSSSVLLFVRSCNSLQAEMNSYE 1182

  Fly  1013 RVMEYVNIPSEPAYETEESVNLPKHWPSGGQLDFRDLRLRYSNHGPYILKGLTFTIRGEEKIGIV 1077
            ||:||..:|.|||......|  |..||..|.:.|..:.:.||..||.|||.:...|...||:.:|
pombe  1183 RVLEYSKLPQEPAPTIAGQV--PATWPKEGDIVFNHVSVSYSAAGPTILKDVNLHINPSEKVAVV 1245

  Fly  1078 GHTAAGKSSIVHALFRLAH-INGHISIDGFETSQLGLHDLRRRISIIPQDPVLFSGSLRFNLDPF 1141
            |.|.:|||::...|.|..| |:|.|.|:|.||..:.|:.||:|||.|||||:||||::|.|||||
pombe  1246 GRTGSGKSTLGLTLLRFTHRISGEIYINGRETQSVNLNALRQRISFIPQDPILFSGTVRSNLDPF 1310

  Fly  1142 EEKTDEELWLALEAVKLKEFVSNLKDG-------INCRLHDCGANFSMGQRQLVCLARALLRQNK 1199
            :|..|..|..||:.......:....|.       ::..:...|:|||.||:|::.||||::|::|
pombe  1311 DELEDNFLNEALKTSGASSMIMAHTDDQKPIHITLDTHVASEGSNFSQGQKQVLALARAIVRRSK 1375

  Fly  1200 ILIMDEATANVDPETDNLIQEAIHTKFAHCTVLTIAHRLHTVMDNDRVMVVDMGRVVELGHPHEL 1264
            |:|:||.||:||...|..||:.:...|...|:|.|||||.|::|.|:|||:|.|.:||.|.|..|
pombe  1376 IIILDECTASVDDAMDQKIQKTLREAFGDATMLCIAHRLKTIVDYDKVMVLDKGVLVEYGPPAVL 1440

  Fly  1265 LHNRHGYLHRFVEKTGV 1281
            .|| :|:..|..:.:|:
pombe  1441 YHN-NGHFRRMCDGSGI 1456

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11898	NP_651679.2	MRP_assoc_pro	2..1268	CDD:188098	372/1237 (30%)
abc4	NP_594558.1	MRP_assoc_pro	277..1456	CDD:188098	374/1245 (30%)