Protein Alignment CG11898 and Abcc2

DIOPT Version :10

• Sequence 1: NP_651679.2
• Gene: CG11898 / 43451
• FlyBaseID: FBgn0039645
• Length: 1320
• Species: Drosophila melanogaster
• Sequence 2: NP_036965.1
• Gene: Abcc2 / 25303
• RGDID: 2366
• Length: 1541
• Species: Rattus norvegicus
• Alignment Length: 1417
• Identity: 425/1417 - (29%)
• Similarity: 701/1417 - (49%)
• Gaps: 213/1417 - (15%)

  Fly    12 PVTKANFFSKWFFIWTREILVKGLQRNLDPSDLYETEPSLESTQVSSFLLGHWEQELKRS----- 71
            |...|:|.|...|.|....::||.:..|...|:::.:...::..|:|.......::|:::
  Rat   193 PSVTASFLSSITFSWYDRTVLKGYKHPLTLEDVWDIDEGFKTRSVTSKFEAAMTKDLQKARQAFQ 257

  Fly    72 --------KPN-------------------------------------VLRMIFKAYGWSFVPAS 91
                    ||.                                     :::.:||.:....:.:.
  Rat   258 RRLQKSQRKPEATLHGLNKKQSQSQDVLVLEEAKKKSEKTTKDYPKSWLIKSLFKTFHVVILKSF 322

  Fly    92 IVYSIMAIAVHTTQPLMLGGLVSFFSESTGKITKHSAYLYAMGVVLCSLISGLFFHPFMKYLFRV 156
            |:..|..:.|. ..|.:|..|:.|...|...:  ...|:.|:.:...:||.......:.::.|.:
  Rat   323 ILKLIHDLLVF-LNPQLLKLLIGFVKSSNSYV--WFGYICAILMFAVTLIQSFCLQSYFQHCFVL 384

  Fly   157 GSRVRLACAGLVYRKFLRVSVAADNSGVSGYAISLMATDLPTFNESFYCFHELWRGPLEGVVFVY 221
            |..||......:|:|.|.:|..|......|..::||:.|.....::......:|...::..:.::
  Rat   385 GMCVRTTVMSSIYKKALTLSNLARKQYTIGETVNLMSVDSQKLMDATNYMQLVWSSVIQITLSIF 449

  Fly   222 IIYQLIGWPAVVGLGTIVAFIPLQAWAARAIARYKRSSADVGDERVKLMNEIIAAMQLIKMYAWE 286
            .:::.:|...:.|:|.:|..||:....|..|...:..:....|:|:|:||||::.::::|.:|||
  Rat   450 FLWRELGPSILAGVGVMVLLIPVNGVLATKIRNIQVQNMKNKDKRLKIMNEILSGIKILKYFAWE 514

  Fly   287 KSFAKLIGKVRKEEMDSIRGSTYIYAGLQCTGMISKLSLFL--------SLVTY-----VFTGDI 338
            .||.:.:..:||:|:.:          |...|.:..|.:|:        |:||:     |.:.::
  Rat   515 PSFQEQVQGIRKKELKN----------LLRFGQLQSLLIFILQITPILVSVVTFSVYVLVDSANV 569

  Fly   339 VTSQKVFIVASYYDHLNDSLLHSWPLAINMWVETFVVANRVKDFLFQHENPADGG---------- 393
            :.::|.|...:.::.|... |...|:..:..::..|..:|::.:|        ||
  Rat   570 LNAEKAFTSITLFNILRFP-LSMLPMVTSSILQASVSVDRLERYL--------GGDDLDTSAIRR 625

  Fly   394 VHNFKEAEDNPEHGNFFGRTHKPKAEVKSITVHKLSASWDQKKQEKRHRHIEDVSFQAQDQQFVG 458
            |.||.                      |::...:.|.:||...:..    |:||:...:..|.|.
  Rat   626 VSNFD----------------------KAVKFSEASFTWDPDLEAT----IQDVNLDIKPGQLVA 664

  Fly   459 IVGTVGAGKSTLLQVILGELDIISGSVEVNGVLSYAPQEPWLLRGSLRDNILFTEPYDEQRYLEV 523
            :|||||:|||:|:..:|||::.:.|.:.:.|..:|.||:.|:..|:::|||||...|:|::|.:|
  Rat   665 VVGTVGSGKSSLVSAMLGEMENVHGHITIQGSTAYVPQQSWIQNGTIKDNILFGSEYNEKKYQQV 729

  Fly   524 LRVCHLDRDVEQLPLGDSTRVGEGGASLSGGQKARVSLARAVYRKADIYLLDDPLSAVDSHVSKM 588
            |:.|.|..|:|.||.||...:||.|.:||||||.|||||||.|:.||||:|||||||||:||.|.
  Rat   730 LKACALLPDLEILPGGDMAEIGEKGINLSGGQKQRVSLARAAYQDADIYILDDPLSAVDAHVGKH 794

  Fly   589 LLDRCL--NEFLSKKIRILVTHRVQLLRHVDHLVLLEGGRISVQGHY-DALKKLIRF-------- 642
            :.::.:  |..|:.|.||.|||.:..|..||.:|:|..|.|..:|.| |.|.|...|
  Rat   795 IFNKVVGPNGLLAGKTRIFVTHGIHFLPQVDEIVVLGKGTILEKGSYRDLLDKKGVFARNWKTFM 859

  Fly   643 -------RMSVANDVE------------------VAKLRAMRTDSVYEEPEPRKSLSQEEHMD-- 680
                   ..:|.||.|                  .|.|...|.:|:      |::||:.....
  Rat   860 KHSGPEGEATVNNDSEAEDDDDGLIPTMEEIPEDAASLAMRRENSL------RRTLSRSSRSSSR 918

  Fly   681 --------------------RHEIEQQ---FKEQQQIGSVKLQTYKEYFKVLGHPLVVVLILLMF 722
                                ..|:|.|   .||..:.|.||...|.:|.:.:|. ..::.|:|.:
  Rat   919 RGKSLKNSLKIKNVNVLKEKEKEVEGQKLIKKEFVETGKVKFSIYLKYLQAVGW-WSILFIILFY 982

  Fly   723 VVARSSEATMDIFLSKWATWEETEPNQHEPIPEYHRTRLRMMILYTFLILCTLIFYVLRTFGFFM 787
            .:...:....:::||.| |.:....|.......:...|:.   ::..|.|...|..::.|.....
  Rat   983 GLNNVAFIGSNLWLSAW-TSDSDNLNGTNNSSSHRDMRIG---VFGALGLAQGICLLISTLWSIY 1043

  Fly   788 MTLRISLRIHDQLFQGVIRAFMHFFTLATSGRILNRFSSDVLAIDVNLPQAMMDSIE--FAVNAL 850
            .....|..:|.||...::||.|.||....:|||:||||.|:..:|..|||.:...:.  |.:...
  Rat  1044 ACRNASKALHGQLLTNILRAPMRFFDTTPTGRIVNRFSGDISTVDDLLPQTLRSWMMCFFGIAGT 1108

  Fly   851 AVLAVVSTANIWLLIPATVVVALLY-GCRCLYIGASRSLKRIETISRSPIYSHTNATFKGLATIR 914
            .|:..::|....::|   :.:::|| ..:..|:..||.|:|::::::||||||.:.|..||..||
  Rat  1109 LVMICMATPVFAIII---IPLSILYISVQVFYVATSRQLRRLDSVTKSPIYSHFSETVTGLPIIR 1170

  Fly   915 ALNGTKYMERDFHYYQNE---NTSALYLHVSINRAFAFWTDLICVLYILAVTFSFLLFDKHRGYY 976
            |.   ::.:|...:.:.:   |...::..::.||..|...:|:..|.:..   |.||...:|...
  Rat  1171 AF---EHQQRFLAWNEKQIDINQKCVFSWITSNRWLAIRLELVGNLVVFC---SALLLVIYRKTL 1229

  Fly   977 SGD-VGLAITQSMKLVLMCQAGMRQTVELENMMTSVERVMEYVNIPSEPAYETEESVNLPKHWPS 1040
            :|| ||..::.::.:.......:|.|.|.|..:.:|||:.||:|:.:|..:.|::  ..|..||.
  Rat  1230 TGDVVGFVLSNALNITQTLNWLVRMTSEAETNIVAVERISEYINVENEAPWVTDK--RPPADWPR 1292

  Fly  1041 GGQLDFRDLRLRYSNHGPYILKGLTFTIRGEEKIGIVGHTAAGKSSIVHALFR-LAHINGHISID 1104
            .|::.|.:.::||......:|||:|..|:..||:|:||.|.|||||:.:.||| |....|.|.||
  Rat  1293 HGEIQFNNYQVRYRPELDLVLKGITCNIKSGEKVGVVGRTGAGKSSLTNCLFRILESAGGQIIID 1357

  Fly  1105 GFETSQLGLHDLRRRISIIPQDPVLFSGSLRFNLDPFEEKTDEELWLALEAVKLKEFVSNLKDGI 1169
            |.:.:.:||||||.|::||||||:|||||||.|||||.:.:|||:|.|||...|:.|||.|:.|:
  Rat  1358 GIDVASIGLHDLRERLTIIPQDPILFSGSLRMNLDPFNKYSDEEVWRALELAHLRSFVSGLQLGL 1422

  Fly  1170 NCRLHDCGANFSMGQRQLVCLARALLRQNKILIMDEATANVDPETDNLIQEAIHTKFAHCTVLTI 1234
            ...:.:.|.|.|:|||||:||.||:||::|||::|||||.||.|||:|||..|..:|:.|||:||
  Rat  1423 LSEVTEGGDNLSIGQRQLLCLGRAVLRKSKILVLDEATAAVDLETDSLIQTTIRKEFSQCTVITI 1487

  Fly  1235 AHRLHTVMDNDRVMVVDMGRVVELGHPHELLHNRHGYLHRFVEKTGVGTAQH 1286
            ||||||:||:|::||:|.|::||.|.|.|||.|| |..:...::.|:....|
  Rat  1488 AHRLHTIMDSDKIMVLDNGKIVEYGSPEELLSNR-GSFYLMAKEAGIENVNH 1538

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11898	NP_651679.2	MRP_assoc_pro	2..1268	CDD:188098	420/1397 (30%)
Abcc2	NP_036965.1	MRP_assoc_pro	7..1533	CDD:188098	423/1410 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	862..881		4/18 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	901..923		5/27 (19%)