Protein Alignment CG11898 and Abcc10

DIOPT Version :10

• Sequence 1: NP_651679.2
• Gene: CG11898 / 43451
• FlyBaseID: FBgn0039645
• Length: 1320
• Species: Drosophila melanogaster
• Sequence 2: NP_001334325.1
• Gene: Abcc10 / 224814
• MGIID: 2386976
• Length: 1526
• Species: Mus musculus
• Alignment Length: 1373
• Identity: 416/1373 - (30%)
• Similarity: 673/1373 - (49%)
• Gaps: 181/1373 - (13%)

  Fly    17 NFFSKWFFIWTREILVKGLQRNL-DPSDLYETEPSLESTQVSSFLLGHWEQELKRSKPNVLRMIF 80
            ::.|::.:.|...:|.:|::..| .|.|.......|....::.....||::..:     :.|.::
Mouse   220 SWLSRFSYAWLAPLLARGVRGELQQPRDTCRLPRRLHPAFLARVFQAHWKEGAQ-----LWRALY 279

  Fly    81 KAYGWSFVPASIVYSIMAIAVHTTQPLMLGGLVSFFSESTGKITKHSAYLYAMGVVLCSLISGLF 145
            :|:|..::...:: .::...:..:.||:|..||.|..|  |:.......||.:|:...::||.:.
Mouse   280 RAFGCCYLALGLL-KMVGTMLGFSGPLLLSLLVGFLEE--GQEPLSHGLLYVLGLAGGTVISAVL 341

  Fly   146 FHPFMKYLFRVGSRVRLACAGLVYRKFLRVSVAADNSGVSGYAISLMATDLPTFNESFYCFHELW 210
            .:.:...:.:|..:.|:|....:|||.|::   ..:...:|..::|:.||..........|||.|
Mouse   342 QNQYGYEVRKVTLQARVAVLSTLYRKALKL---GPSRPPTGEVLNLLGTDSERLLNFAGSFHEAW 403

  Fly   211 RGPLEGVVFVYIIYQLIGWPAVVGLGTIVAFIPLQAWAARAIARYKRSSADVGDERVKLMNEIIA 275
            ..||:..:.:|::||.:|...:.||...:..:|:....|..|....:......|.|||||.|:::
Mouse   404 GLPLQLAITLYLLYQQVGMAFLAGLVLALLLVPVNKVIATRIMASNQEMLRHKDARVKLMTELLS 468

  Fly   276 AMQLIKMYAWEKSFAKLIGKVRKEEMDSIRGSTYIYAGLQCTGMISKLSLFLSL---VTYVFTGD 337
            .:::||.:.||::....:...|.:|:..:|...|:.|.  |..:.:.|.:.:.:   :|||..|.
Mouse   469 GIRVIKFFRWEQALGDRVKACRTKELGRLRVIKYLDAA--CVYLWAALPVVICITIFITYVLMGH 531

  Fly   338 IVTSQKVFIVASYYDHLNDSLLHSWPLAINMWVETFVVANRVKDFLFQHENPADGGVHNFKEAED 402
            .:|:.|||...:....| ...|:::|..||..:|:.|..:|::.||                  |
Mouse   532 QLTATKVFTALALVRML-ILPLNNFPWVINGLLESKVSLDRIQRFL------------------D 577

  Fly   403 NPEHGNFFGRTHKPKAEVK-SITVHKLSASWDQ--KKQEKRHRHIEDVSFQAQDQQFVGIVGTVG 464
            .|.:......:..|.||.. ::.:|:...|||.  ..|:....|:     |.:....|||||.||
Mouse   578 LPSYSPEAYYSPDPPAEPSTALELHEALFSWDPIGASQKTFISHL-----QVKKGMLVGIVGKVG 637

  Fly   465 AGKSTLLQVILGELDIISGSVEVNGV---LSYAPQEPWLLRGSLRDNILFTEPYDEQRYLEVLRV 526
            .|||:||..|.|||..:.|.|.|:.:   ...|.||||:...::||||||.:.:|.|.|.|||..
Mouse   638 CGKSSLLAAITGELHRLCGWVAVSELSKGFGLATQEPWIQCATIRDNILFGKTFDAQLYREVLEA 702

  Fly   527 CHLDRDVEQLPLGDSTRVGEGGASLSGGQKARVSLARAVYRKADIYLLDDPLSAVDSHVSKMLLD 591
            |.|:.|:..||.||.|.|||.|.:|||||:||::||||||::..:|||||||:|||:.|:..||.
Mouse   703 CALNDDLSILPAGDQTEVGEKGVTLSGGQRARIALARAVYQEKALYLLDDPLAAVDADVANHLLH 767

  Fly   592 RCLNEFLSKKIRILVTHRVQLLRHVDHLVLLEGGRISVQGHYDALKKLIRFRMSVANDVEVAKLR 656
            ||:...||...|:|.|||.:.|...|.::|:|.|::...|....:..|::
Mouse   768 RCILGVLSHTTRLLCTHRTEYLERADVVLLMEAGQLVRTGPPSEILPLVQ--------------- 817

  Fly   657 AMRTDSVYEEPEPRKSLSQ-----------EEHMDRHEIEQQF------KEQQQIGSVKLQTYKE 704
              ...:.:.|.|...:..|           ||.:   |:||..      :|.:..|:|.|..|:.
Mouse   818 --AVPTAWAEKEQVATSGQSPSVCDLERTTEEEL---EVEQSTCGCLVQEESKSEGAVALHVYRA 877

  Fly   705 YFKVLGHPL-VVVLILLMFVVARSSEATMDIFLSKWATWEETEPNQHEPIP---EYHRTRL---R 762
            |::.:|..| ..:|:.|:.:.|..:.|  |.:|:.|.:..:...|.....|   ....|.|   |
Mouse   878 YWRAMGSGLAAAILVSLLLMQATRNGA--DWWLAHWLSQLKAGRNGSREDPASCSPGSTALFSPR 940

  Fly   763 MMI-----LYTFLI------------------------------LCTLIFYVLRTFGFFMMTLRI 792
            :::     |||.|:                              ||||:..||...|    .|:.
Mouse   941 LLLFSPGNLYTPLLSTPLHKAASNGTADVHFYLIVYATIAGVNSLCTLLRAVLFAAG----ALQA 1001

  Fly   793 SLRIHDQLFQGVIRAFMHFFTLATSGRILNRFSSDVLAIDVNLPQAMMDSIEFAVNALAVLAVVS 857
            :..:|.:|...::.|.:.|:....|||:||||||||..:|.:||..:...:..:|..|.:|||:.
Mouse  1002 AASLHHRLLHRLLMAPVTFYDSTPSGRVLNRFSSDVACVDDSLPFLLNILLANSVGLLGLLAVLG 1066

  Fly   858 TANIWLLIPATVVVALLYGCRCLYIGASRSLKRIETISRSPIYSHTNATFKGLATIRALNGTKYM 922
            :...|||:....:..:.|..:..|..:.|.|:|:.:::.||:|||...|..||..:||...|
Mouse  1067 SGLPWLLLLLPPLSFVYYSVQGYYRASFRELRRLGSLTWSPLYSHLADTLAGLPVLRAAGAT--- 1128

  Fly   923 ERDFHYYQNENTSALYLHVSINRAFAF-------WTDLICVLY---ILAVTFSFLLFDKHRGYYS 977
                :.::.||...|    .:|:...|       |.|:...|.   :::......|....:|..:
Mouse  1129 ----YRFEEENQRLL----ELNQRCQFASYATMQWLDIRLQLMGAAVVSAIAGIALVQHQQGLAN 1185

  Fly   978 -GDVGLAITQSMKLVLMCQAGMRQTVELENMMTSVERVMEY-VNIPSEPAYETEESVNLPK-HWP 1039
             |.|||.::.::.|..:....:....:.|.||.||||:.|| .::|.||..:..:|.:..: .|.
Mouse  1186 PGLVGLVLSYALSLTGLLSGLVSSFTQTEAMMVSVERLEEYSCDVPQEPHSQPLQSPHQQRISWL 1250

  Fly  1040 SGGQLDFRDLRLRYSNHGPYILKGLTFTIRGEEKIGIVGHTAAGKSSIVHALFRLAHIN-GHISI 1103
            :.|.::|:|:.|.|....|..|.|:||.:...||:||||.|.:||||:...||||...| |.:.:
Mouse  1251 TQGSVEFQDVVLVYRPGLPNALDGVTFRVEPGEKLGIVGRTGSGKSSLFLVLFRLLEPNAGRVLL 1315

  Fly  1104 DGFETSQLGLHDLRRRISIIPQDPVLFSGSLRFNLDPFEEKTDEELWLALEAVKLKEFV------ 1162
            |..:||||.|.:||.::::|||:|.||||::|.||||.....|..||.|||...|.|..
Mouse  1316 DNVDTSQLELAELRSQLAVIPQEPFLFSGTIRENLDPQGLHEDRALWQALEQCHLSEVAVAMGES 1380

  Fly  1163 ------------------SNLKDGINCRLHDCGANFSMGQRQLVCLARALLRQNKILIMDEATAN 1209
                              :.|..|::..|.:.|.|.|:|||||:|||||||...|||.:|||||:
Mouse  1381 QACQRSQREAKNGHWQCSALLTGGLDGELGERGQNLSLGQRQLLCLARALLTDAKILCIDEATAS 1445

  Fly  1210 VDPETDNLIQEAIHTKFAHCTVLTIAHRLHTVMDNDRVMVVDMGRVVELGHPHELLHNRHGYLHR 1274
            ||.:||.|:|:.|..:||:.|||||||||:|::::|||:|:..||||||..|..|.:..|....:
Mouse  1446 VDQKTDQLLQQTICKRFANKTVLTIAHRLNTILNSDRVLVLQAGRVVELDSPSALRNQPHSLFQQ 1510

  Fly  1275 FVEKTGVG 1282
            .::.:..|
Mouse  1511 LLQSSQQG 1518

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11898	NP_651679.2	MRP_assoc_pro	2..1268	CDD:188098	414/1357 (31%)
Abcc10	NP_001334325.1	MRP_assoc_pro	203..1503	CDD:188098	414/1356 (31%)