Protein Alignment CG11898 and tap2

DIOPT Version :9

• Sequence 1: NP_651679.2
• Gene: CG11898 / 43451
• FlyBaseID: FBgn0039645
• Length: 1320
• Species: Drosophila melanogaster
• Sequence 2: XP_002942649.3
• Gene: tap2 / 100489020
• XenbaseID: XB-GENE-481680
• Length: 728
• Species: Xenopus tropicalis
• Alignment Length: 647
• Identity: 163/647 - (25%)
• Similarity: 286/647 - (44%)
• Gaps: 126/647 - (19%)

  Fly   669 PRKSLSQEEHMDRHEIEQQFKEQQQIGSVKLQTYK--EYFKVLGHPLVVVLILL--MFV---VAR 726
            |.||.         |.|...|::::...::|..|.  ::..:.|..:.:.|.|:  ||:   :.|
 Frog   136 PNKSA---------EGEANSKKRERENFIRLLKYSIPDWLPLCGAFVFLTLALIGEMFIPYYMGR 191

  Fly   727 SSEATMDIFLSKWATWEETEPNQHEPIPEYHRTRLRMMILYTFLILCTLIFYVLRTFGFFMMTL- 790
                .:||.        .|..|:.|        .||.|.......:.:.||...|. |.||.:|
 Frog   192 ----VIDIL--------STNYNERE--------FLRAMSFMAMFSITSSIFAGSRG-GLFMFSLA 235

  Fly   791 RISLRIHDQLFQGVIRAFMHFFTLATSGRILNRFSSDV------LAIDVNLPQAMM------DSI 843
            |::.|:...||:.||:..:.||....||.|.:|.::|.      :|.:||:...|:      .|.
 Frog   236 RLTQRLRLLLFRSVIKQEIAFFEATKSGDITSRLTNDTARVSRSIAANVNITLRMLVKCVGVYSF 300

  Fly   844 EFAVN-ALAVLAVVSTANIWLLIPATVVVALLYGCRCLYIGASRSLKRI-ETISRSPIYSHTNAT 906
            .|::: .|.:|..:|:       |.|.::..:|.    |.... .:||: ::|:||     :...
 Frog   301 MFSLSWQLTLLTFISS-------PLTWIIQKVYN----YYHQD-LVKRVQDSIARS-----SELA 348

  Fly   907 FKGLATIRALNGTKYMERDFHYYQNENTSALYLHVSINRAFAFWTDLICVLYILAVTFSFLLFDK 971
            .:.:.::|.:......|.:...|:|   |....||...|     .|.:..||:|......|....
 Frog   349 KEIIESVRNVYSFAAEEEEAKRYEN---SLQETHVLQTR-----RDFVTALYLLVTRLVNLGTQV 405

  Fly   972 HRGYY-----------SGDVGLAITQSMKLVLMCQAGMRQTVELENMMTSVERVMEYVNIPSEPA 1025
            ...||           ||.:...|...|:.....:..:....|:.:...:.|:|.:|::  .||.
 Frog   406 TMLYYGQILIRSGFISSGKMVSFILYQMESDSYIRTLVHMLSEITHAAGAAEKVFQYLD--REPQ 468

  Fly  1026 YETEESVNLPKHWPSG--------GQLDFRDLRLRYSNHGPYI--LKGLTFTIRGEEKIGIVGHT 1080
            ...           ||        |:.:|.::...|.:. |.|  |:.::||:.......:||.:
 Frog   469 VSA-----------SGCLCPGTLQGRFEFSNVTFSYPSR-PEILALQNVSFTLPPGSVTALVGPS 521

  Fly  1081 AAGKSSIVHALFRLAH-INGHISIDGFETSQLGLHDLRRRISIIPQDPVLFSGSLRFNLD----- 1139
            ..||::.|..|.|... ..|:|.:||....:.....|..:::::.|:||||:||:|.|:.
 Frog   522 GGGKTTCVSLLERFYEPQGGNILLDGKPLKEYKHEYLHSKVALVAQEPVLFAGSVRENISYGLYN 586

  Fly  1140 -PFEEKTDEELWLALEAVKLKEFVSNLKDGINCRLHDCGANFSMGQRQLVCLARALLRQNKILIM 1203
             |     :|:|..|....|.::|:..::...:..:.:.||..|.||:|.|.|||||.|:.|:||:
 Frog   587 IP-----EEKLKAAARKAKAEDFIEGMEKAYDTDVGNSGAQLSAGQKQRVALARALARKPKLLIL 646

  Fly  1204 DEATANVDPETDNLIQEAIHTKFAHCTVLTIAHRLHTVMDNDRVMVVDMGRVVELGHPHELL 1265
            |||::.:|.||::.||:::.: ....::|.|||||.||...|:::|::.|.:||.| .||.|
 Frog   647 DEASSCLDAETEHEIQKSLQS-IEDLSLLIIAHRLRTVQKADQILVLEAGNLVEQG-THEKL 706

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11898	NP_651679.2	CFTR_protein	9..1268	CDD:273530	163/647 (25%)
		ABC_membrane	92..358	CDD:294371
		ABCC_MRP_domain1	423..626	CDD:213217
		ABC_membrane	762..988	CDD:294371	58/251 (23%)
		ABCC_MRP_domain2	1042..1261	CDD:213211	73/227 (32%)
tap2	XP_002942649.3	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000