Protein Alignment CG11898 and abcc2

DIOPT Version :10

• Sequence 1: NP_651679.2
• Gene: CG11898 / 43451
• FlyBaseID: FBgn0039645
• Length: 1320
• Species: Drosophila melanogaster
• Sequence 2: XP_004915926.1
• Gene: abcc2 / 100485020
• XenbaseID: XB-GENE-1012796
• Length: 1552
• Species: Xenopus tropicalis
• Alignment Length: 1429
• Identity: 448/1429 - (31%)
• Similarity: 708/1429 - (49%)
• Gaps: 216/1429 - (15%)

  Fly     1 MSAVHEQRQPNPVTKANFFSKWFFIWTREILVKGLQRNLDPSDLYETEPSLESTQVSSFLLGHWE 65
            :|..:|..:.||...|:|.|:..|.|...|:|||.::.|:..||:|.....::..:......|.:
 Frog   192 ISEKNESTKENPELTASFLSRITFNWYNSIVVKGYKKPLEMEDLWELNEEDKTKNMYEIFEKHMK 256

  Fly    66 QELKRSKPNV---------------LRMIFKAYG------------------------------W 85
            .:::::|.::               :..|.||..                              |
 Frog   257 HDVRKAKKDLEKRKNKRKQKESGIEMNGISKAQSQDILVMEEKKKEKKKKEKSIDGTAKDYPKRW 321

  Fly    86 ----------SFVPASIVYSIMAIAVHTTQPLMLGGLVSFFSESTGKITKH--SAYLYAMGVVLC 138
                      |.:..|.::.::...:....|.:|..:|:|    |...::|  ..:.||:.:::.
 Frog   322 LIKTLIKTFPSTLLTSAIFKLLHDLLAFVSPQILKVMVTF----TADPSQHQWQGFFYAVLLLVT 382

  Fly   139 SLISGLFFHPFMKYLFRVGSRVRLACAGLVYRKFLRVSVAADNSGVSGYAISLMATDLPTFNESF 203
            :|:.......:....|.:|.|||......||:|.|.||.|.......|..::||:.|...|.:..
 Frog   383 ALLQSFLLQQYFHGCFVLGMRVRSLLMAAVYKKALTVSNAIRKESTVGETVNLMSADAQRFMDLT 447

  Fly   204 YCFHELWRGPLEGVVFVYIIYQLIGWPAVVGLGTIVAFIPLQAWAARAIARYKRSSADVGDERVK 268
            ...|.||..||:..:.:..:::.:|...:.|||.::..||:.|..|....:.:..:....|:|:|
 Frog   448 NFIHLLWSSPLQIAISIVFLWEELGPSVLAGLGVMILLIPINAVLATVSRKLQMKNMKNKDKRMK 512

  Fly   269 LMNEIIAAMQLIKMYAWEKSFAKLIGKVRKEEMDSIRGSTYIYAGLQCTGMISKLSLF------- 326
            :||||:..::::|:||||.||...:.::|::|:..:...||:::          :|||
 Frog   513 IMNEILNGIKILKLYAWEPSFENQVQEIREKELKDMLHFTYLHS----------VSLFVFTCAPF 567

  Fly   327 -LSLVTY-----VFTGDIVTSQKVFIVASYYDHLNDSLLHSWPLAINMWVETFVVANRVKDFLFQ 385
             :|:.|:     |...:::.::|.|...|.::.|...|. ..|:.|:..|:|.|.:.|::.:|
 Frog   568 LVSVATFAVYVAVDPSNVLNAEKAFTSISLFNILRFPLA-MLPMLISSMVQTSVSSARLEKYL-- 629

  Fly   386 HENPADGGVHNFKEAEDNPEHGNFFGRTHKPKAEVKSITVHKLSASWDQKKQEKRHRHIEDVSFQ 450
                  ||        ||.:....   ...|..:. ::.....:.||    :|..:..:.:|:..
 Frog   630 ------GG--------DNLDTSAI---RCDPNIDA-AVQFSDATFSW----EEDANPAVNNVNLD 672

  Fly   451 AQDQQFVGIVGTVGAGKSTLLQVILGELDIISGSVEVNGVLSYAPQEPWLLRGSLRDNILFTEPY 515
            .::...|.:||.||:|||:|:..:|||:|.:.|.:.:.|.::|.||:.|:...:|::||||....
 Frog   673 IKEGNLVAVVGGVGSGKSSLVSAMLGEMDHVGGYINIKGSIAYVPQQAWIQNATLKNNILFGSKM 737

  Fly   516 DEQRYLEVLRVCHLDRDVEQLPLGDSTRVGEGGASLSGGQKARVSLARAVYRKADIYLLDDPLSA 580
            ||:||.:||..|.|..|:|.||..|.:.:||.|.:||||||.|||||||||..||||:|||||||
 Frog   738 DEERYQKVLEACALLPDLEMLPGHDESEIGEKGINLSGGQKQRVSLARAVYNDADIYILDDPLSA 802

  Fly   581 VDSHVSKMLLDRCL--NEFLSKKIRILVTHRVQLLRHVDHLVLLEGGRISVQGHYDALKKLIRFR 643
            ||:||.|.:.::.:  |..|..|.||||||.|..|:|.|.:|:|...|::..|.|..|:
 Frog   803 VDAHVGKHIFEKVVGPNGLLKNKTRILVTHGVSFLKHADDIVVLVNSRVTETGSYKTLQ------ 861

  Fly   644 MSVAND---VEVAKLRAMRTDSVYEEPEPRKSLSQEEHMDRHEIEQQF----------------- 688
               ||:   .|..:|.|.:.|....|.........|:..|:.|..:..
 Frog   862 ---ANNGAFAEFLRLYAKQNDQTDNEATVFTGEDDEDDGDQVETAEVIEDIVASTVKRENSMRQR 923

  Fly   689 -------------------------------------KEQQQIGSVKLQTYKEYFKVLGHPLVVV 716
                                                 ||..:.|.||.:.|.:|.:.:|... ..
 Frog   924 KRSSVSMNGTLRRSVKDVTKKKTGIGSNDTKGQKLIEKETVETGKVKFKLYLKYLRAVGWGF-SF 987

  Fly   717 LILLMFVVARSSEATMDIFLSKWATWEETEPNQHEPIPEYHRTRLRMMILYTF--LILCTLIFYV 779
            .|.:.:::..::....:|:||.|....|...|...|..:      |.|.:..|  |.:...:|.:
 Frog   988 WIFVSYILQNAAFVGQNIWLSDWTGDAEKYYNITYPASQ------RDMRVGVFGALGVAQALFVL 1046

  Fly   780 LRTFGFFMMT---LRISLRIHDQLFQGVIRAFMHFFTLATSGRILNRFSSDVLAIDVNLPQAMMD 841
            |   |.|:::   :|.|..:|.||...::|..|.||....:|||:|||:.|:|.:|..:|.:...
 Frog  1047 L---GAFLVSGGAVRASRMLHTQLLHNILRVPMRFFDTTPTGRIVNRFAKDILTVDETIPMSFRS 1108

  Fly   842 SIEFAVNALAVLAVVSTANIWLLIPATVVVAL---LYGCRCLYIGASRSLKRIETISRSPIYSHT 903
            .|...:..:..|.::..|.   .|.|.|:|.|   .|..:..|:..||.|:|:::::|||||||.
 Frog  1109 WIACFLGVIGTLFIICLAT---PIFAAVIVPLAIFYYFVQRFYVTTSRQLRRLDSVTRSPIYSHF 1170

  Fly   904 NATFKGLATIRALNGTKYMERDFHYYQNENT-----SALYLHVSINRAFAFWTDLICVLYILAVT 963
            ..|..||:.|||     |..:|.....||:|     .::|..:..||..|...:.:   ..|.|.
 Frog  1171 GETVSGLSVIRA-----YGHQDRFLQHNEDTIDNNQKSVYSWIVSNRWLAIRLEFV---GNLTVF 1227

  Fly   964 FSFLLFDKHRGYY-SGDVGLAITQSMKLVLMCQAGMRQTVELENMMTSVERVMEYVNIPSEPAYE 1027
            |:.|.....||.. ||.|||:|:.::.:.......:|.|.|||..:.:||||.||:.:..|..:
 Frog  1228 FAALFAVLGRGTVDSGTVGLSISSALNITQTLNWLVRMTSELETNIVAVERVDEYIKVEREAQW- 1291

  Fly  1028 TEESVNLPKHWPSGGQLDFRDLRLRYSNHGPYILKGLTFTIRGEEKIGIVGHTAAGKSSIVHALF 1092
             .|....||.||..|.:.|.|.::||......:|:|::.||...||:||||.|.|||||:.:.:|
 Frog  1292 -VEDHRPPKDWPEKGVVQFVDYKVRYRPELDLVLQGISCTINSMEKVGIVGRTGAGKSSLTNCIF 1355

  Fly  1093 RLAH-INGHISIDGFETSQLGLHDLRRRISIIPQDPVLFSGSLRFNLDPFEEKTDEELWLALEAV 1156
            |:.. ..|.|.|||.:.:.:||||||::::|||||||||||:||.|||||.:.|||::|.|||..
 Frog  1356 RIIESAGGKIMIDGLDIASIGLHDLRQKLTIIPQDPVLFSGNLRMNLDPFNQYTDEDIWKALELS 1420

  Fly  1157 KLKEFVSNLKDGINCRLHDCGANFSMGQRQLVCLARALLRQNKILIMDEATANVDPETDNLIQEA 1221
            .||.||..|::.:...:.:.|.|.|:||||||||||||||::||||:|||||.||.|||||||..
 Frog  1421 HLKPFVEGLQEKLFHEVSEGGENLSVGQRQLVCLARALLRKSKILILDEATAAVDLETDNLIQRT 1485

  Fly  1222 IHTKFAHCTVLTIAHRLHTVMDNDRVMVVDMGRVVELGHPHELLHNRHGYLHRFVEKTGVGTAQ 1285
            |.::||.||||||||||||:||:.|:||:|.|:::|.|.|.||| .|.|:.....:..|:.:.|
 Frog  1486 IRSEFADCTVLTIAHRLHTIMDSSRLMVLDAGKIIEFGSPDELL-QRQGHFFSMAKDAGIDSTQ 1548

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11898	NP_651679.2	MRP_assoc_pro	2..1268	CDD:188098	444/1409 (32%)
abcc2	XP_004915926.1	MRP_assoc_pro	10..1544	CDD:188098	446/1423 (31%)