Protein Alignment rdog and NFT1

DIOPT Version :10

• Sequence 1: NP_651678.1
• Gene: rdog / 43450
• FlyBaseID: FBgn0039644
• Length: 1374
• Species: Drosophila melanogaster
• Sequence 2: NP_013029.3
• Gene: NFT1 / 853978
• SGDID: S000001811
• Length: 1218
• Species: Saccharomyces cerevisiae
• Alignment Length: 1067
• Identity: 242/1067 - (22%)
• Similarity: 455/1067 - (42%)
• Gaps: 238/1067 - (22%)

  Fly    63 AELWEDELKRSNPSVV----------RM---ILRAYGKIFV-PMGLAF--SISETICKSLMPLFL 111
            |::|:.::...:.:::          |:   |:..:..:|: .:.|||  |....:...|||..|
Yeast   272 ADIWDLDINNKSIAILANFEMSSKKGRLLPNIICYFKAVFISQLFLAFVSSFLNFVPSLLMPRIL 336

  Fly   112 GGLVGYFATNQTDISENTAYLYAMGIVICMLVPVITFHPFIFYIFQVGT-KLRLALSGLIYRKVL 175
            .     :..:....|.|...||...:::..:: ..|......::.:.|| :||..|...||.|.|
Yeast   337 S-----YVNDPKSKSWNLVSLYVSSMLVSKII-ATTCRGQGLFLGEKGTMQLRTVLISNIYSKTL 395

  Fly   176 QVS------------------------------KSSSNDGLRGRAINILSNDLGRFDVALCFLHD 210
            :.:                              |||..|   ....|::|.|..:...|:...:.
Yeast   396 RRTILKDSTTSLQKNASTSFEENPDSSEAEPRKKSSRKD---NSVNNVMSIDAFKVSEAMNTFYL 457

  Fly   211 TWKGPMESILIGFLMYREIGISAVIGVSFMLSFIPLQAWAAKKAAYYRQMTAER---TDMRVKLM 272
            ..:....::....::|..:|.||..|...:|:.|||..|.   |.:|....|::   ||.|...:
Yeast   458 ACEAVFMTVTALMILYSLLGWSAFAGTFALLAMIPLNFWC---ATFYGNYQADQLILTDKRTSGI 519

  Fly   273 NEIIQGIQVIKMYAWEKSFARVIAEVRLKEVKAIRGTAYI----HAA--LGCTSMISPL--SVFL 329
            :|.:..|:|||:.|||..|.:.|..||..|::.::..|.|    |..  .|.| ::|.:  |||:
Yeast   520 SEALNSIRVIKLLAWENLFYQKIINVRDGEIRLLKKKATIFFLNHLIWFFGPT-LVSAITFSVFI 583

  Fly   330 ALCSYVYLGDPLTAQKVYTVSSYFNMLNDSMVTFWPMSITFIAEALVSAKRCKDFLLDGDKAEVP 394
            .     :....||....:|..|.|.:|...|... ..:::.:.::.:|.:|.:|:|.:.:..:..
Yeast   584 K-----FQNQTLTPTIAFTALSLFAILRTPMDQI-ASTVSLLIQSFISLERIQDYLNESETRKYE 642

  Fly   395 INLEANQQTGKNKRKISKKDKQKNVELNGSLLSNGQVHHNRLRDYDPEATKKCVVLKNVSASWDT 459
            |..::|.:.|                                             .::.|..|:.
Yeast   643 ILEQSNTKFG---------------------------------------------FEDASMEWEA 662

  Fly   460 SDGHANCAIEDFSTDIKDQTLAAVVGPVGAGKSSFLNVLLGEVGIDKGEAMVH----------GK 514
            ::  .:..:::.|.|.|..:|.|::||.|:||||.|..||||:.:..|:..|.          ||
Yeast   663 AE--TSFKLKNISIDFKLNSLNAIIGPTGSGKSSLLLGLLGELNLLSGKIYVPTVESRDDLEIGK 725

  Fly   515 ------ISYASQESWVFEGTIRDNIVFVEDYNERRYKKVVKVCGLERDMELLPRGDLTVVGERGV 573
                  ::|.||..|:..|||:||:||.|.:|::::..|:|.|.|::|::.:..|..|.||:.|.
Yeast   726 DGMTNSMAYCSQTPWLISGTIKDNVVFGEIFNKQKFDDVMKSCCLDKDIKAMTAGIRTDVGDGGF 790

  Fly   574 SLSGGQKARVSLARAVYRKADIYLLDDPLSAVDTHVGKHIFDRCI-RDFLSNKIRILVTHQVQYL 637
            ||||||:.|::||||:|..:...:|||.|||||.....:|::.|: ...:..:..|:.:|.:..:
Yeast   791 SLSGGQQQRIALARAIYSSSRYLILDDCLSAVDPETALYIYEECLCGPMMKGRTCIITSHNISLV 855

  Fly   638 FD-VEHLLLMGSGKIMAQGSYQELQRSRQFQFLEQTQHDESGIDTHSVSSYLSRSDSEKSME--- 698
            .. .:.|:::..|::.:||...:|.:|.  :||.::.:::|...||:... |.||.:.|..:
Yeast   856 TKRADWLVILDRGEVKSQGKPSDLIKSN--EFLRESINNDSKNTTHNQID-LKRSTTSKKTKNGD 917

  Fly   699 ----HQHNQLLRPDEHVEDVNQEQQTVGSIKMHVY---ASYIKALDSTFLLGIVISLFVCARIML 756
                :..:::....|:.|:...|    ||:|...|   |.|...|.       |:.:|..:.|::
Yeast   918 PEGGNSQDEVCAEVENFEETKME----GSVKFSAYKWLADYFGGLG-------VVFVFTSSSILI 971

  Fly   757 TGV----DYFLSRWVIWEEQIAVNRTTTLLNETDTTIANDTLPINATDPY----------IAPLL 807
            .|:    .::|..|:                :|.::.:..|......:.:          |..|:
Yeast   972 HGITLSQGFWLRYWL----------------DTGSSGSKSTWLYRIVEGHSNIYFLLTYIIIGLV 1020

  Fly   808 ASDIQAGIRQELVLFYATILGATLIVYLIRTFGFFKMCLRISLHLHDRLFRGITRASMYFFNTNS 872
            :|.:.:|     .::.|.|.|.                 .::..:..:|...|..|.:.|.|...
Yeast  1021 SSFLTSG-----KVWIAIISGT-----------------NVTKKIFAKLLSSILYAKLRFHNVTP 1063

  Fly   873 SGRILNRFSKDIRTVDTD-------LPHTLLDCLAFIIDVSGVVIIVAIANYWLLIPAAIIGVIL 930
            :|||:||||||:..:|..       |.::::.||       .:::::.......|:.|..:..:.
Yeast  1064 TGRIMNRFSKDMDIIDQQLIPNFEGLSYSVVVCL-------WIILLIGYVTPQFLLFAIPLCALY 1121

  Fly   931 GMIRYLYVNTSRSVKRLESISRSPVFSLTNQTFQGLTTIRAL-QAQSALEQEFHEYQNTNTSAWF 994
            ..:..||:..||.:||:::|:.||:..|..:..:|:|||||| ..:..:.|.......:|...::
Yeast  1122 YTVCTLYLRASRELKRIDNINISPIHQLFAEAIKGVTTIRALADERRFITQSLVAIDRSNAPFFY 1186

  Fly   995 LFLSCTRAFALWSDVLCIVYMTAVTFS 1021
            |.::..     |......:..|.|.||
Yeast  1187 LNMATE-----WITYRVDIIGTLVLFS 1208

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rdog	NP_651678.1	MRP_assoc_pro	14..1323	CDD:188098	242/1067 (23%)
NFT1	NP_013029.3	MRP_assoc_pro	252..>1218	CDD:188098	242/1067 (23%)