Protein Alignment rdog and BPT1

DIOPT Version :10

• Sequence 1: NP_651678.1
• Gene: rdog / 43450
• FlyBaseID: FBgn0039644
• Length: 1374
• Species: Drosophila melanogaster
• Sequence 2: NP_013086.1
• Gene: BPT1 / 850645
• SGDID: S000003938
• Length: 1559
• Species: Saccharomyces cerevisiae
• Alignment Length: 1445
• Identity: 451/1445 - (31%)
• Similarity: 702/1445 - (48%)
• Gaps: 233/1445 - (16%)

  Fly    15 FTKANFFSQWSFWWMRDLFKRGLQGPLTDEELYQHRKTLDSER------------VTNKFAELWE 67
            :...:..|..:|.||..|.          .|.|:::|..|..:            ::.:|...||
Yeast   216 YPPVHVLSYITFIWMNKLI----------VETYRNKKIKDPNQLPLPPVDLNIKSISKEFKANWE 270

  Fly    68 DELKRSNPSVVRMILRAYGKIFVPMGLAFSISETICKSLMP----LFLGGLVGYFATNQTDISE- 127
            .|...:..|:.|.|.:::|:. :.:.:.:..:..:...:.|    :|:.||      |....|:
Yeast   271 LEKWLNRNSLWRAIWKSFGRT-ISVAMLYETTSDLLSVVQPQFLRIFIDGL------NPETSSKY 328

  Fly   128 ---NTAYLYAMGIVICMLVPVITFHPFIFYIFQVGTKLRLALSGLIYRKVLQVSKSSSNDGLRGR 189
               |..:: |:.:.:..:|.|...:.|...||:.|..:|.:|:.|:|:|.|:::.:..|:...|.
Yeast   329 PPLNGVFI-ALTLFVISVVSVFLTNQFYIGIFEAGLGIRGSLASLVYQKSLRLTLAERNEKSTGD 392

  Fly   190 AINILSNDLGR----FDVALCFLHDTWKGPMESILIGFLMYREIGISAVIGVSFMLSFIPLQAWA 250
            .:|::|.|:.|    |:.|...:    ..|::.|::...:|..:|.:.:.|:..|...:|:.|:.
Yeast   393 ILNLMSVDVLRIQRFFENAQTII----GAPIQIIVVLTSLYWLLGKAVIGGLVTMAIMMPINAFL 453

  Fly   251 AKKAAYYRQMTAERTDMRVKLMNEIIQGIQVIKMYAWEKSFARVIAEVR----LKEVKAIRGTA- 310
            ::|.....:...:..|||:|.:.|::..|:.||:||||:.....:..||    ||..:.|...:
Yeast   454 SRKVKKLSKTQMKYKDMRIKTITELLNAIKSIKLYAWEEPMMARLNHVRNDMELKNFRKIGIVSN 518

  Fly   311 YIHAALGCTSMISPLSVFLALCSYVYLGDPLTAQKVYTVSSYFNMLNDSMVTFWPMSITFIAEAL 375
            .|:.|..|..::...|.| .|.| ::...||:...|:...|.||:||.::.:. |..|..|.|..
Yeast   519 LIYFAWNCVPLMVTCSTF-GLFS-LFSDSPLSPAIVFPSLSLFNILNSAIYSV-PSMINTIIETS 580

  Fly   376 VSAKRCKDFLL--------------DGDKAEVPINLEANQQTGKNKRKISKKDKQKNVELNGSLL 426
            ||.:|.|.|||              ..|:..:|. :|.|..|...|.|              .:|
Yeast   581 VSMERLKSFLLSDEIDDSFIERIDPSADERALPA-IEMNNITFLWKSK--------------EVL 630

  Fly   427 SNGQVHHNRLRDYDPEATKKCVVLKNVSASWDTSDGHANCAIEDFSTDIKDQTLAAVVGPVGAGK 491
            ::.|...|...|.:.......:.|||               |:.|  :.|...|..|||.|||||
Yeast   631 TSSQSGDNLRTDEESIIGSSQIALKN---------------IDHF--EAKRGDLVCVVGRVGAGK 678

  Fly   492 SSFLNVLLGEVGIDKGE--------AMVHGKISYASQESWVFEGTIRDNIVFVEDYNERRYKKVV 548
            |:||..:||::....|.        .:....::|.|||||:...::|:||:|...:::..|...:
Yeast   679 STFLKAILGQLPCMSGSRDSIPPKLIIRSSSVAYCSQESWIMNASVRENILFGHKFDQDYYDLTI 743

  Fly   549 KVCGLERDMELLPRGDLTVVGERGVSLSGGQKARVSLARAVYRKADIYLLDDPLSAVDTHVGKHI 613
            |.|.|..|:::||.||.|:|||:|:|||||||||:|||||||.:||||||||.|||||..|.|:|
Yeast   744 KACQLLPDLKILPDGDETLVGEKGISLSGGQKARLSLARAVYSRADIYLLDDILSAVDAEVSKNI 808

  Fly   614 FDRCI---RDFLSNKIRILVTHQVQYLFDVEHLLLMGSGKIMAQGSYQELQR-----SRQFQFLE 670
            .:..:   ...|.||..||.|:.|..|...:.:..:.:|:|:.||:|:::..     |:..:.||
Yeast   809 IEYVLIGKTALLKNKTIILTTNTVSILKHSQMIYALENGEIVEQGNYEDVMNRKNNTSKLKKLLE 873

  Fly   671 --------------QTQH-DESGID-------THSVSSYLSRSDSEKSMEHQHNQ-----LLRPD 708
                          ||:| .||.:|       |.|.:.....::||..:...:::     .|||.
Yeast   874 EFDSPIDNGNESDVQTEHRSESEVDEPLQLKVTESETEDEVVTESELELIKANSRRASLATLRPR 938

  Fly   709 EHV----EDVNQ-----EQQTVGSIKMHVYASYIKALDSTFLLGIVI-SLF-VCARIMLTGVDYF 762
            ..|    :.|.:     |:..||.:|..:|.:||||..   :||:|: .|| :..|:.....:::
Yeast   939 PFVGAQLDSVKKTAQKAEKTEVGRVKTKIYLAYIKACG---VLGVVLFFLFMILTRVFDLAENFW 1000

  Fly   763 LSRWVIWEEQIAVNRTTTLLNETDTTIANDTLPINATDPYIAPLLASDIQAGIRQELVLFYATIL 827
            |..|....|:...|....:.....:.|.                :||.....:|..::|.|.:|.
Yeast  1001 LKYWSESNEKNGSNERVWMFVGVYSLIG----------------VASAAFNNLRSIMMLLYCSIR 1049

  Fly   828 GATLIVYLIRTFGFFKMCLRISLHLHDRLFRGITRASMYFFNTNSSGRILNRFSKDIRTVDTDLP 892
            |                    |..||:.:.:.:.|:.|.||.|...|||:||||.|:..||::|.
Yeast  1050 G--------------------SKKLHESMAKSVIRSPMTFFETTPVGRIINRFSSDMDAVDSNLQ 1094

  Fly   893 HTLLDCLAFIIDVSGVVIIVAIANYWLLIPAAIIGVILGMIRYLYVNTSRSVKRLESISRSPVFS 957
            :........|:.....||:|.....|.|:....:.||....:..|:..||.:|||.|||.||:.|
Yeast  1095 YIFSFFFKSILTYLVTVILVGYNMPWFLVFNMFLVVIYIYYQTFYIVLSRELKRLISISYSPIMS 1159

  Fly   958 LTNQTFQGLTTIRALQAQSALEQEFHEYQNTNTSAWFLFLSCTRAFALWSDV------LCIVYMT 1016
            |.:::..|.:.|.|...........:|....|....|.|.|..|    |..|      ..||..|
Yeast  1160 LMSESLNGYSIIDAYDHFERFIYLNYEKIQYNVDFVFNFRSTNR----WLSVRLQTIGATIVLAT 1220

  Fly  1017 AV-TFSFLLLKDEFDSGDVGLAILHSTTMTGMCQWGMRQTAELENQMTSVERVLEYTEQPSEALL 1080
            |: ..:.:..|.:..||.|||.:.:|..:||...|.:|.|..:|..:.||||::||.|.|.||..
Yeast  1221 AILALATMNTKRQLSSGMVGLLMSYSLEVTGSLTWIVRTTVTIETNIVSVERIVEYCELPPEAQS 1285

  Fly  1081 ETPEKFKPKSEWPSKGRIEFINFKLRYSPKEAPVLKDLNFTIEPREKIGIVGRTGAGKSSIIQSI 1145
            ..||| :|...|||||.|||.|:..:|.....|||.::|..|||.||:|||||||||||::..::
Yeast  1286 INPEK-RPDENWPSKGGIEFKNYSTKYRENLDPVLNNINVKIEPCEKVGIVGRTGAGKSTLSLAL 1349

  Fly  1146 FR-LACNEGMIRIDDVDIEHIGLHDLRSQVSIIPQDPVLFSGTLRYNLDPMDERSDEEMWKALGD 1209
            || |...||.|.||.:||..|||.||||.::|||||...|.||::.||||.:..|::|:.:|:..
Yeast  1350 FRILEPTEGKIIIDGIDISDIGLFDLRSHLAIIPQDAQAFEGTVKTNLDPFNRYSEDELKRAVEQ 1414

  Fly  1210 VELRSYVSTLI-------------GGLN----CRMYDGGSNFSVGQRQLVCLARAILRHNKILIM 1257
            ..|:.::..::             |.:|    .::.:.|||.|||||||:|||||:|..:|||::
Yeast  1415 AHLKPHLEKMLHSKPRGDDSNEEDGNVNDILDVKINENGSNLSVGQRQLLCLARALLNRSKILVL 1479

  Fly  1258 DEATANVDPETDKLIQQTIRSKFAHCTVLTIAHRLHTVMDSDRVLVMDAGEVRELGHPYELLQ-- 1320
            |||||:||.||||:||.|||.:|...|:||||||:.||:|||:::|:|.|.|||...|.:||.
Yeast  1480 DEATASVDMETDKIIQDTIRREFKDRTILTIAHRIDTVLDSDKIIVLDQGSVREFDSPSKLLSDK 1544

  Fly  1321 --------RTGGYLR 1327
                    ..||||:
Yeast  1545 TSIFYSLCEKGGYLK 1559

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rdog	NP_651678.1	MRP_assoc_pro	14..1323	CDD:188098	447/1439 (31%)
BPT1	NP_013086.1	MRP_assoc_pro	222..1556	CDD:188098	447/1434 (31%)