Protein Alignment rdog and l(2)03659

DIOPT Version :10

• Sequence 1: NP_651678.1
• Gene: rdog / 43450
• FlyBaseID: FBgn0039644
• Length: 1374
• Species: Drosophila melanogaster
• Sequence 2: NP_610482.3
• Gene: l(2)03659 / 47905
• FlyBaseID: FBgn0010549
• Length: 1374
• Species: Drosophila melanogaster
• Alignment Length: 1389
• Identity: 558/1389 - (40%)
• Similarity: 828/1389 - (59%)
• Gaps: 138/1389 - (9%)

  Fly     3 RTRRKVVRPKNPFTKANFFSQWSFWWMRDLFKRGLQGPLTDEELYQHRKTLDSERVTNKFAELWE 67
            :..::.|.|:||..::||.|...||:...:|::|.:..|...:||:..:...|:.:.|:....||
  Fly    79 QNEKEKVLPENPRARSNFISSLCFWYTIPIFRKGYRKTLDSTDLYRPLEEQKSDILGNRLCASWE 143

  Fly    68 DELKRS--NPSVVRMILRAYG-KIFVPMGLAFSISETICKSLMPLFLGGLVGYFATNQTDISENT 129
            .|||..  :||:||.:||.:| ::..| |||..:.|...::|.|:||..|:.|| :.:.| :.|.
  Fly   144 RELKNDGRSPSLVRALLRVFGWQLGFP-GLAIFVVELGLRTLQPIFLVKLISYF-SGEPD-AANA 205

  Fly   130 AYLYAMGIVICMLVPVITFHPFIFYIFQVGTKLRLALSGLIYRKVLQVSKSSSNDGLRGRAINIL 194
            .:.||:..::...:.|:...|..|.|..|..|:|:|:..:|:||.|:::|.:..|...|..:|::
  Fly   206 GFYYAVAQIVISALTVMILTPTTFGIHHVCFKMRVAMGSMIFRKALRLTKGALGDTTSGHVVNLI 270

  Fly   195 SNDLGRFDVALCFLHDTWKGPMESILIGFLMYREIGISAVIGVSFMLSFIPLQAWAAKKAAYYRQ 259
            |||:.|.|.|...:|..|.||::.::|.:|||:|||||||.||.|||.|:|:|.:...:.:..:.
  Fly   271 SNDIPRLDSAPYTVHYLWVGPLQVLVITYLMYQEIGISAVFGVLFMLLFMPIQMYLGTRTSAIQL 335

  Fly   260 MTAERTDMRVKLMNEIIQGIQVIKMYAWEKSFARVIAEVRLKEVKAIRGTAYIHA-ALGCTSMIS 323
            ..|||||.|::::||||..|||:||||||:.|.:::...|.||:..||...||.. ......::|
  Fly   336 KAAERTDNRIRMVNEIISAIQVLKMYAWEQPFEQMVTHAREKEMNTIRQGQYIRGFDFARRIVLS 400

  Fly   324 PLSVFLALCSYVYLGDPLTAQKVYTVSSYFNMLNDSMVTFWPMSITFIAEALVSAKRCKDF---- 384
            .:::||:|..||.||...|.:..:.:::|:|:|..:|..:.|.:|...|:.|.|.:|.:.|
  Fly   401 RVAIFLSLVGYVILGKVFTPEIAFMITAYYNVLLAAMSIYVPSAIIQTAQFLTSIRRVEQFMQSE 465

  Fly   385 -LLDGDKAEVPINLEANQQTGKNKRKISKKDKQKNVELNGSLLSNGQVHHNRLRDYDPEATKKCV 448
             |...||:|.|                 .||     .:.|:..||..         :.:..|..:
  Fly   466 ELGSSDKSEGP-----------------SKD-----TVPGNPPSNNN---------EADLLKSAI 499

  Fly   449 VLKNVSASWDTSDGHANCAIEDFSTDIKDQTLAAVVGPVGAGKSSFLNVLLGEVGIDKGEAMVHG 513
            .::::.|.||.:.  .:..:...:.:||..::.||:|..|:||||.:..:|||:..:.|:..|:|
  Fly   500 SIRDLKAKWDPNS--PDYTLSGINLEIKPGSVVAVIGLTGSGKSSLIQAILGELKANSGQLQVNG 562

  Fly   514 KISYASQESWVFEGTIRDNIVFVEDYNERRYKKVVKVCGLERDMELLPRGDLTVVGERGVSLSGG 578
            .:||.|||||:|.||:|.||:|.:..:.:||::|||.|.||||.:|||..|.|:|||||.:||||
  Fly   563 SLSYTSQESWLFSGTVRQNILFGQPMDSQRYEEVVKKCALERDFDLLPLRDNTIVGERGATLSGG 627

  Fly   579 QKARVSLARAVYRKADIYLLDDPLSAVDTHVGKHIFDRCIRDFLSNKIRILVTHQVQYLFDVEHL 643
            ||||:||||:|||||.||||||||||||..|.:|:||:|:|..|.....:|||||.|:|..|:.:
  Fly   628 QKARISLARSVYRKASIYLLDDPLSAVDASVARHLFDQCVRGHLRGSTVVLVTHQEQFLPHVDQI 692

  Fly   644 LLMGSGKIMAQGSYQELQRSRQFQFLEQTQHDESGIDTHSVSSYLSRSDSEKSMEHQHNQLLRPD 708
            :::.:|:|.|.|.|:.|.:              :|:.|...|  ||::|..|:.|.:...|..||
  Fly   693 VILANGQIKALGDYESLLK--------------TGLITGLGS--LSKTDKAKTEEQEPLNLNSPD 741

  Fly   709 -----------------------EHVEDVNQEQQTVGSIKMHVYASYIKALDSTFLLGIVISLFV 750
                                   |||     |:|..|.|.:.:|..|.:|........:::|..|
  Fly   742 NKNEVTPIKENSEQTVGGSSSGKEHV-----ERQESGGISLALYRKYFQAGGGLVAFLVMLSSSV 801

  Fly   751 CARIMLTGVDYFLSRWVIWEEQIAVNRTTTLLNETDTTIAN----DTLPINATDPYIAPLLASDI 811
            .|::.:||.||||:.||                :.::|.|.    :.:...:.|.|
  Fly   802 LAQVAVTGGDYFLTYWV----------------KKESTAAGHGEMEDMESKSMDVY--------- 841

  Fly   812 QAGIRQELVLFYATILGATLIVYLIRTFGFFKMCLRISLHLHDRLFRGITRASMYFFNTNSSGRI 876
                      .|..|:..::|:.|..:|..|.:..:.|:.||:.:|..:|||.|:||:.|..|.|
  Fly   842 ----------KYTLIIILSVIMNLSSSFLLFNIAKKASIRLHNTIFNRVTRADMHFFSINKHGSI 896

  Fly   877 LNRFSKDIRTVDTDLPHTLLDCLAFIIDVSGVVIIVAIANYWLLIPAAIIGVILGMIRYLYVNTS 941
            ||||:||:..||..||..|:|.:...:.::|::|::|..|..||:|..::.||...:|.||:.||
  Fly   897 LNRFTKDMSQVDEVLPVVLVDVMQIALWLAGIIIVIANVNPLLLVPTLMLSVIFYHLRNLYLKTS 961

  Fly   942 RSVKRLESISRSPVFSLTNQTFQGLTTIRALQAQSALEQEFHEYQNTNTSAWFLFLSCTRAFALW 1006
            |.:||:|:|:||||:|....:..||||||||.||..||:||..||:.::||:|:::|.::||...
  Fly   962 RDLKRVEAINRSPVYSHLAASLNGLTTIRALDAQRVLEKEFDSYQDAHSSAFFMYISTSQAFGYC 1026

  Fly  1007 SDVLCIVYMTAVTFSFLLLKDEFDSG---DVGLAILHSTTMTGMCQWGMRQTAELENQMTSVERV 1068
            .:.:|::|::.:|.||.    .|..|   ||||.|..:..:..|.|||:||||||||.||:||||
  Fly  1027 MNCICVIYISIITLSFF----AFPPGNGADVGLVITQAMGLIDMVQWGVRQTAELENTMTAVERV 1087

  Fly  1069 LEYTEQPSEALLETPEKFKPKSEWPSKGRIEFINFKLRYSP--KEAPVLKDLNFTIEPREKIGIV 1131
            :||.....|.:||.|:..||...||.:|.|.|....|||:|  |...|||.|:|.|:||||:|||
  Fly  1088 VEYESIEPEGMLEAPDDKKPPKTWPEQGEIIFKELNLRYTPNAKAENVLKSLSFVIQPREKVGIV 1152

  Fly  1132 GRTGAGKSSIIQSIFRLACNEGMIRIDDVDIEHIGLHDLRSQVSIIPQDPVLFSGTLRYNLDPMD 1196
            |||||||||:|.::|||:..:|.:.||..|...:||||||.|:|||||:|||||||:||||||.|
  Fly  1153 GRTGAGKSSLINALFRLSYTDGSVLIDTRDTRQMGLHDLRRQISIIPQEPVLFSGTMRYNLDPFD 1217

  Fly  1197 ERSDEEMWKALGDVELRSYVSTLIGGLNCRMYDGGSNFSVGQRQLVCLARAILRHNKILIMDEAT 1261
            |.|||::|..|.:|:|:..||.|..||..::.:||:||||||||||||||||||.|:||:|||||
  Fly  1218 EYSDEKLWGCLEEVKLKEVVSDLPDGLASKISEGGTNFSVGQRQLVCLARAILRENRILVMDEAT 1282

  Fly  1262 ANVDPETDKLIQQTIRSKFAHCTVLTIAHRLHTVMDSDRVLVMDAGEVRELGHPYELLQRTGG-Y 1325
            |||||:||.|||.||||||..||||||||||||::|||:|:|||||.|.|.|.||||:.::.. .
  Fly  1283 ANVDPQTDGLIQATIRSKFRDCTVLTIAHRLHTIIDSDKVMVMDAGRVVEFGSPYELMTKSDSKV 1347

  Fly  1326 LRQLVDNTGAATSFALQQAAEQSY 1349
            ...||:.:|.|:...|.:.|::::
  Fly  1348 FHNLVNQSGRASYEGLLKIAQETF 1371

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rdog	NP_651678.1	MRP_assoc_pro	14..1323	CDD:188098	549/1349 (41%)
l(2)03659	NP_610482.3	PLN03130	83..1369	CDD:215595	558/1381 (40%)