Protein Alignment rdog and Mrp4

DIOPT Version :10

• Sequence 1: NP_651678.1
• Gene: rdog / 43450
• FlyBaseID: FBgn0039644
• Length: 1374
• Species: Drosophila melanogaster
• Sequence 2: NP_650086.2
• Gene: Mrp4 / 41387
• FlyBaseID: FBgn0263316
• Length: 1316
• Species: Drosophila melanogaster
• Alignment Length: 1367
• Identity: 578/1367 - (42%)
• Similarity: 830/1367 - (60%)
• Gaps: 97/1367 - (7%)

  Fly    11 PKNPFTKANFFSQWSFWWMRDLFKRGLQGPLTDEELYQHRKTLDSERVTNKFAELWEDEL-KRSN 74
            |:||..:::..|...|.:...:..:|.:..|..::||:..|...|:.:.::....|:::: |...
  Fly    10 PENPRERSSPLSSLMFCFALPVLFKGRKKTLEQKDLYRALKEHKSDSLGDRLCAAWDEQVAKNET 74

  Fly    75 PSVVRMILRAYGKIFVPMGLAFSISETICKSLMPLFLGGLVGYFATNQTDISENTAYLYAMGIVI 139
            |.:.|.:.:.:|......|:.....|.:.|...|:.|.|::.|||.|..|.|:  |.|:|.|::.
  Fly    75 PRLGRALTKVFGFHLFITGVFLLAQEFLTKVTQPICLIGVMAYFAGNDPDRSK--AQLWAAGLIA 137

  Fly   140 CMLVPVITFHPFIFYIFQVGTKLRLALSGLIYRKVLQVSKSSSNDGLRGRAINILSNDLGRFDVA 204
            ..:..|...||::..:..:|.|:|:|||.|||||.|::|:::..|...|:.:|:||||:||||:.
  Fly   138 GSVFSVCIGHPYMLGLLHLGMKMRIALSSLIYRKALRLSRTALGDTTVGQVVNLLSNDVGRFDLV 202

  Fly   205 LCFLHDTWKGPMESILIGFLMYREIGISAVIGVSFMLSFIPLQAWAAKKAAYYRQMTAERTDMRV 269
            |..:|..|..|:|.|.:.:|||.|||||::.||:.||.|:|.|::..|:.:..|..||.|||.||
  Fly   203 LINVHYLWIAPLELIAVTYLMYLEIGISSMFGVAIMLLFLPFQSYLGKRTSVLRLRTALRTDERV 267

  Fly   270 KLMNEIIQGIQVIKMYAWEKSFARVIAEVRLKEVKAIRGTAYIHAALGCTSM-ISPLSVFLALCS 333
            ::|||||.||||||||||||.|.:|:...|..|:..|:...||...|...:| :|.:....:|.:
  Fly   268 RMMNEIISGIQVIKMYAWEKPFGKVVEMTRFNEMLCIKQVNYIRGILISFAMFLSRIFTSSSLIA 332

  Fly   334 YVYLGDPLTAQKVYTVSSYFNMLNDSMVTFWPMSITFIAEALVSAKRCKDFLLDGDKAEVPINLE 398
            :|.||:.|.|:|.:.|::|:|:|..|:..|:|..|:..||.|||.:|.:.|:   .:.|..:
  Fly   333 FVLLGNILNAEKAFFVTAYYNILRRSVTMFFPQGISEFAELLVSVRRLEAFM---HRPETKV--- 391

  Fly   399 ANQQTGKNKRKISKKDKQKNVELNG-SLLSNGQVHHNRLRDYDPEATKKCVVLKNVSASWDTSDG 462
                  ::|.|: |...||....|| |...||          .||   ..:......|.|::
  Fly   392 ------RDKSKV-KNANQKAESPNGDSPKGNG----------IPE---NLIEFSQFQARWES--- 433

  Fly   463 HA-NCAIEDFSTDIKDQTLAAVVGPVGAGKSSFLNVLLGEVGIDKGEAMVHGKISYASQESWVFE 526
            |: ...:||.:..:..:.|.||:|||||||||.:..:|||:..:.|...::|..|||:||.|:|.
  Fly   434 HSLEPTLEDINLQLGRRKLVAVIGPVGAGKSSLIQAILGELPGESGTLRINGSYSYAAQEPWLFT 498

  Fly   527 GTIRDNIVFVEDYNERRYKKVVKVCGLERDMELLPRGDLTVVGERGVSLSGGQKARVSLARAVYR 591
            ||:|.||:|..|:::.||:.|||.|.||||.||||.||.|:|||||.|||||||||:||||||||
  Fly   499 GTVRQNILFGLDWDKHRYRTVVKKCALERDFELLPFGDKTIVGERGASLSGGQKARISLARAVYR 563

  Fly   592 KADIYLLDDPLSAVDTHVGKHIFDRCIRDFLSNKIRILVTHQVQYLFDVEHLLLMGSGKIMAQGS 656
            :||||||||||||||||||:|:||:|:|.:|.:::.||||||:|:|...:.:::|..|:|.|.|:
  Fly   564 RADIYLLDDPLSAVDTHVGRHLFDQCMRGYLRSELVILVTHQLQFLEQADLIVIMDKGRISAMGT 628

  Fly   657 YQELQRS-RQF-QFLEQTQHDE-----------SGIDTHSVSSYLSRSDSEKSMEHQHNQLLRPD 708
            |..::|| ..| |.|.....|.           .|:|..:|.|...|.........::|......
  Fly   629 YSSMKRSGLDFAQLLTAPNKDAEDLDEIDGAGGDGLDLLNVPSLSRRGSKNSKPSTRNNSFTSLS 693

  Fly   709 EHVEDVNQE-----QQT--VGSIKMHVYASYIKALDSTFLLGIVISLFVCARIMLTGVDYFLSRW 766
            ...|.:.||     |:|  .|.|.:.:|..|:.:..|.|::..::.|.:..:|:.:..|||||.|
  Fly   694 SMAESMAQEASLQMQETRVEGKIGLGLYKEYLTSGSSWFMIFFMVFLCLATQILCSAADYFLSYW 758

  Fly   767 VIWEEQIAVNRTTTLLNETDTTIANDTLPINATDPYIAPLLASDIQAGIRQELVLFYATILGATL 831
            |                  |..:...| .|| |||               |:  ::|...|...:
  Fly   759 V------------------DKNVDGQT-DIN-TDP---------------QD--MYYFAALNVAV 786

  Fly   832 IVY-LIRTFGFFKMCLRISLHLHDRLFRGITRASMYFFNTNSSGRILNRFSKDIRTVDTDLPHTL 895
            :|: ::||..|:||.:|.|..||:.:::|||||:|||||||.|||||||||||:..:|..||..:
  Fly   787 VVFTIVRTMLFYKMAMRSSTQLHNAMYQGITRAAMYFFNTNPSGRILNRFSKDLGQLDEVLPSVM 851

  Fly   896 LDCLAFIIDVSGVVIIVAIANYWLLIPAAIIGVILGMIRYLYVNTSRSVKRLESISRSPVFSLTN 960
            ||.:...:.:.|:::::.|.|.:.||....:.:|...||..|:.|||.|||||:::|||::|..:
  Fly   852 LDVVQLFLTLLGIIVVICITNPYYLILTLALAIIFYYIREFYLKTSRDVKRLEAVARSPIYSHLS 916

  Fly   961 QTFQGLTTIRALQAQSALEQEFHEYQNTNTSAWFLFLSCTRAFALWSDVLCIVYMTAVTFSFLLL 1025
            .|..||.|||||.||..|..||...|:.::|.::.||:..|||..:.|..|.:|:..:..::.:.
  Fly   917 ATITGLPTIRALGAQKELIAEFDNLQDLHSSGYYTFLATNRAFGYYLDCFCTLYIVIIILNYFIN 981

  Fly  1026 KDEFDSGDVGLAILHSTTMTGMCQWGMRQTAELENQMTSVERVLEYTEQPSEALLETPEKFKPKS 1090
            ..: ..|:|||||..:..||||.||.|||:|||||.||:||||:||.|...|...::.|..||..
  Fly   982 PPQ-SPGEVGLAITQAMGMTGMVQWAMRQSAELENTMTAVERVVEYDEIEPEGEFDSREGKKPSP 1045

  Fly  1091 EWPSKGRIEFINFKLRY--SPKEAPVLKDLNFTIEPREKIGIVGRTGAGKSSIIQSIFRLACNEG 1153
            .||.||.|...:..|||  .|:...|||.|||.|.|.||:||||||||||||:|.::|||:.|||
  Fly  1046 SWPEKGEIIAEDLCLRYFPDPQAKYVLKALNFRIRPCEKVGIVGRTGAGKSSLINALFRLSYNEG 1110

  Fly  1154 MIRIDDVDIEHIGLHDLRSQVSIIPQDPVLFSGTLRYNLDPMDERSDEEMWKALGDVELRSYVST 1218
            :|.||:.|...:||.||||::|||||:||||||::||||||.:|.:|.::|.||.:|:|:..:|.
  Fly  1111 IITIDERDTADMGLFDLRSKISIIPQEPVLFSGSMRYNLDPFEEYNDAKLWDALEEVKLKPLISE 1175

  Fly  1219 LIGGLNCRMYDGGSNFSVGQRQLVCLARAILRHNKILIMDEATANVDPETDKLIQQTIRSKFAHC 1283
            |..||..::.:|||||||||||||||||||||.|::|:||||||||||:||.|||.||||||..|
  Fly  1176 LPNGLQSKISEGGSNFSVGQRQLVCLARAILRENRVLVMDEATANVDPQTDALIQATIRSKFRDC 1240

  Fly  1284 TVLTIAHRLHTVMDSDRVLVMDAGEVRELGHPYELLQRTGGYL-RQLVDNTGAATSFALQQAAEQ 1347
            |||||||||:|:||||||||||||.:.|.|.|||||..:...: ..:|..||..|..:|.:.||:
  Fly  1241 TVLTIAHRLNTIMDSDRVLVMDAGHLVEFGSPYELLTSSESKIFHGMVMETGQNTFDSLLKVAEK 1305

  Fly  1348 SY 1349
            ::
  Fly  1306 AH 1307

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rdog	NP_651678.1	MRP_assoc_pro	14..1323	CDD:188098	569/1335 (43%)
Mrp4	NP_650086.2	MRP_assoc_pro	13..1292	CDD:188098	570/1347 (42%)