Protein Alignment rdog and abc4

DIOPT Version :10

• Sequence 1: NP_651678.1
• Gene: rdog / 43450
• FlyBaseID: FBgn0039644
• Length: 1374
• Species: Drosophila melanogaster
• Sequence 2: NP_594558.1
• Gene: abc4 / 2543059
• PomBaseID: SPAC30.04C
• Length: 1469
• Species: Schizosaccharomyces pombe
• Alignment Length: 1322
• Identity: 380/1322 - (28%)
• Similarity: 623/1322 - (47%)
• Gaps: 191/1322 - (14%)

  Fly    66 WEDELKR-SNPSVVRMILRAYGKIFVPMGLAFSISETICKSLMPLFLGGLVGYFATNQTDISENT 129
            |....:| ..||:...|.:.:.:..:.||:: |...::|:.|.|:.|..|:.:..:..:. |.|.
pombe   272 WTYRFERMKTPSLFITIHKIFWRQILGMGVS-SFMVSVCQFLSPIALNRLLKHLESPSSS-SVNP 334

  Fly   130 AYLYAMGIVICMLVPVITFHPFIFYIFQVGTKLRLALSGL---IYRKVL--QVSKSSSNDGLRGR 189
                .:.||:.:..|.:|.....||:|.....|..:.:.|   ||.||:  :..::.|.|...||
pombe   335 ----LVWIVLLLTGPFLTSLFTQFYLFMSTRYLARSYTTLVQQIYNKVIRSRFVQNKSGDSKVGR 395

  Fly   190 AINILSNDLGRFDVALCFLHDTWKGPMESILIGFLMYREIGISAVIGVSF--MLSFIP--LQAWA 250
            :.|::|.|:........|:|...:.|:|.....:|:.:.:|.||.:|::.  :...:|  |....
pombe   396 SNNLISTDVDDIGEIREFIHIIVRAPVEIAGSIYLLQKLLGWSAYVGLALTVLTCSVPIVLGPLV 460

  Fly   251 AKKAAYYRQMTAER-TDMRVKLMNEIIQGIQVIKMYAWEKSFARVIAEVRLKEVKAIRGTAYIHA 314
            ||..     :.|.| ||.|::||:|::|.|::.|.:.||......:.:.|  :|:..|....:..
pombe   461 AKLT-----LRANRATDSRIELMSELLQSIRITKFFGWELPMLDRVKQRR--QVELNRTWKLLLM 518

  Fly   315 ALGCTSMISPLSVFLALCSYV----YLGDPLTAQKVYTVSSYFNMLNDSMVTFWPMSITFIAEAL 375
            .:....::..|.||....::|    .:|..:|....:|..|.|:.:. :..::....:..|.:..
pombe   519 EICIQVLVESLPVFSMFATFVVFTTIMGQTITPSIAFTSISLFSFIR-TQFSWIAYLMRQIVQIF 582

  Fly   376 VSAKRCKDFLLDGDKAEVPINL--EANQQTGKNKRKISKKDKQKNVELNGSLLSNGQVHHNRLRD 438
            ||..|..|||.|.|:.: |:|.  :.:|:.|
pombe   583 VSIGRVSDFLNDPDEVD-PVNTIEDTSQEIG---------------------------------- 612

  Fly   439 YDPEATKKCVVLKNVSASWDTSDGHANCAIEDFSTDIKDQTLAAVVGPVGAGKSSFLNVLLGEVG 503
                       ..|.|.:|.::....:..:.|.:.......|:.|:||.|:||||.::.||||:.
pombe   613 -----------FFNASLTWVSNPSPGDFCLRDLNIVFPRNKLSIVIGPTGSGKSSLISALLGELS 666

  Fly   504 IDKGE-AMVHGK-ISYASQESWVFEGTIRDNIVFVEDYNERRYKKVVKVCGLERDMELLPRGDLT 566
            ::||. .:...| :||.||..|:...||||||:|...|.|.|||||::.|||..|::.....|||
pombe   667 LNKGSYNLPRSKGVSYVSQVPWLRNATIRDNILFDYPYIEERYKKVIQACGLLTDLQSFVASDLT 731

  Fly   567 VVGERGVSLSGGQKARVSLARAVYRKADIYLLDDPLSAVDTHVGKHIFDRCIR-DFLSNKIRILV 630
            .:||:||:||||||.|::||||||....|.|:||..||:|.|....|:..|.: ..:.|:..|||
pombe   732 EIGEKGVTLSGGQKQRIALARAVYSPTSIVLMDDVFSALDIHTSNWIYKHCFQSSLMENRTVILV 796

  Fly   631 THQVQYLFDVEHLLLMGSGKIMA--QGS-YQELQRSRQFQFL--EQTQHDESGIDTHSVSSYLSR 690
            ||.|       ||.:..:..|:.  .|| :....:|....||  :.....|:.....:.....:.
pombe   797 THNV-------HLFMDSAAFIVTVKNGSAFPVTDKSSPLLFLAEQAASASEAAAPDLAAIPIPNE 854

  Fly   691 SDSEKSMEHQHNQLLRPDEHVEDVNQEQQTVGSIKMHVYASYIKALDSTFLLGIVISLFVCARIM 755
            .|..::.:.:..:|         |.:||:..|.:......||:|...|.|.:..|:..||..:..
pombe   855 VDDAEAADEKDGKL---------VEEEQRVTGDVVFSEIFSYMKHFGSGFYVAAVLLFFVTTQAT 910

  Fly   756 LTGVDYFLSRWVIWEEQIAVNRTTTLLNETDTTIANDTLPINATDPYIAPLLASDIQAGIRQELV 820
            ...:|.:::.|           |.:.:|..|..                           ..:.:
pombe   911 SILIDLWVAFW-----------TNSSVNSPDVN---------------------------NNKFL 937

  Fly   821 LFYATILGATLIVYLIRTFGFFKMCLRISLHLHDRLFRGITRASMYFFNTNSSGRILNRFSKDIR 885
            ..|.|:|.|..::..:||..:.:.....|..|||.:...:......:|:...:|||:|||:||||
pombe   938 FVYGTMLLAYSLLDFLRTVSYDRGAWWASRKLHDSMLESVFGTFASWFDKTPTGRIVNRFAKDIR 1002

  Fly   886 TVDTDLPHTLLDCLAFIIDVSGVVIIVAIANYWLLIPAAII---GVILGMIRYLYVNTSRSVKRL 947
            ::|.:|...|...:...:.|:|.::.|:.|....:|||.|:   |...|:   ||......||||
pombe  1003 SIDMNLSGWLFFSINCFLSVAGGILSVSSAMPIFMIPAVIVCLAGYYFGL---LYTRAQVGVKRL 1064

  Fly   948 ESISRSPVFSLTNQTFQGLTTIRALQAQSALEQEFHE-------YQNT--NTSAWFLFLSCTRAF 1003
            .||..||:|||..::..|::.|||...|:..:|.|.|       .|:|  |.:.|         .
pombe  1065 ISIYTSPIFSLLGESIVGVSVIRAFNRQTIFKQMFSERLDNLVRLQSTSYNLNRW---------V 1120

  Fly  1004 ALWSDVLCIVYMTAVTFSFLLLKDEFDSGDVGLAILHSTTMTGMCQWGMRQTAELENQMTSVERV 1068
            |:.:|.:..: :.|:.....||:.:...|.||.::..:...:......:|....|:.:|.|.|||
pombe  1121 AVRTDGISGL-VGAIAGLIALLQKDLSPGVVGFSLNQAVIFSSSVLLFVRSCNSLQAEMNSYERV 1184

  Fly  1069 LEYTEQPSEALL----ETPEKFKPKSEWPSKGRIEFINFKLRYSPKEAPVLKDLNFTIEPREKIG 1129
            |||::.|.|...    :.|      :.||.:|.|.|.:..:.||.....:|||:|..|.|.||:.
pombe  1185 LEYSKLPQEPAPTIAGQVP------ATWPKEGDIVFNHVSVSYSAAGPTILKDVNLHINPSEKVA 1243

  Fly  1130 IVGRTGAGKSSIIQSIFRLACN-EGMIRIDDVDIEHIGLHDLRSQVSIIPQDPVLFSGTLRYNLD 1193
            :|||||:|||::..::.|.... .|.|.|:..:.:.:.|:.||.::|.|||||:|||||:|.|||
pombe  1244 VVGRTGSGKSTLGLTLLRFTHRISGEIYINGRETQSVNLNALRQRISFIPQDPILFSGTVRSNLD 1308

  Fly  1194 PMDERSDEEMWKALGDVELRSYVSTLIGG-----------LNCRMYDGGSNFSVGQRQLVCLARA 1247
            |.||..|..:.:||    ..|..|::|..           |:..:...|||||.||:|::.||||
pombe  1309 PFDELEDNFLNEAL----KTSGASSMIMAHTDDQKPIHITLDTHVASEGSNFSQGQKQVLALARA 1369

  Fly  1248 ILRHNKILIMDEATANVDPETDKLIQQTIRSKFAHCTVLTIAHRLHTVMDSDRVLVMDAGEVREL 1312
            |:|.:||:|:||.||:||...|:.||:|:|..|...|:|.|||||.|::|.|:|:|:|.|.:.|.
pombe  1370 IVRRSKIIILDECTASVDDAMDQKIQKTLREAFGDATMLCIAHRLKTIVDYDKVMVLDKGVLVEY 1434

  Fly  1313 GHPYELLQRTGGYLRQLVDNTG 1334
            |.| .:|....|:.|::.|.:|
pombe  1435 GPP-AVLYHNNGHFRRMCDGSG 1455

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rdog	NP_651678.1	MRP_assoc_pro	14..1323	CDD:188098	376/1309 (29%)
abc4	NP_594558.1	MRP_assoc_pro	277..1456	CDD:188098	379/1317 (29%)