Protein Alignment rdog and abc1

DIOPT Version :10

• Sequence 1: NP_651678.1
• Gene: rdog / 43450
• FlyBaseID: FBgn0039644
• Length: 1374
• Species: Drosophila melanogaster
• Sequence 2: NP_594585.1
• Gene: abc1 / 2542640
• PomBaseID: SPAC9E9.12C
• Length: 1427
• Species: Schizosaccharomyces pombe
• Alignment Length: 1374
• Identity: 371/1374 - (27%)
• Similarity: 644/1374 - (46%)
• Gaps: 213/1374 - (15%)

  Fly     7 KVVRPKNPFTKANFFSQWSFWWMRDLFKRGLQGPLTDEELYQHRKTLDSERVTNKFAELWEDEL- 70
            ||.||....|.:.|...:::.|:..:..:..:.|:|..::    ..|.....|    ::|....
pombe   187 KVARPSPEQTCSIFSLIFTYGWLNGIIWKSWKKPITLTDV----PALPDTECT----QIWYSRFA 243

  Fly    71 KRSNPSVVRMILRAY-GKIFVPMGLAFSISETICKSLMPLFLGGLVGYFATNQTDISENTAYLYA 134
            |....|::..||.:. ..|.:.:.|:..:|.|:  .:.||.:..|:.|....::| ..|:.:|:.
pombe   244 KNDRKSLMHTILLSLKSTILLMVFLSVLVSSTL--FVTPLAIKKLLQYLQNPKSD-EGNSPFLWV 305

  Fly   135 MGIVICMLVPVITFHPFIFYIFQVGTKLRLALSGLIYRKVLQVSKS--SSNDGLR---GRAINIL 194
            ..::|...:..:....::....:...:::.|::.:||:||| .||:  .:.||.:   ....|:|
pombe   306 FVLLIGPYLASVVKELYVHVSRRFMLRIKAAITQMIYKKVL-TSKTLFVAVDGSKINLDYVYNLL 369

  Fly   195 SNDLGRFDVALCFLHDTWKGPMESILIGFLMYREIGISAVIG--VSFMLSFIPLQAWAAKKAAYY 257
            :.|:........|:....:.|:|..:..:.:|:.:|.||.:|  ::.:.|..||  ..|.|.:..
pombe   370 AKDVDNIGEMREFIGIIARAPLEMGVSMYFLYQLLGWSAYVGLLLAILSSSFPL--LVASKISRL 432

  Fly   258 RQMTAERTDMRVKLMNEIIQGIQVIKMYAWEKSFARVIAEVRLKEVKAIRGTAYIHAALGCTSMI 322
            ..:....:|.|::|..|:::.|::.|::.||:.....|.|.|..||..:...............|
pombe   433 TSIANTSSDERIRLTTELLKSIKITKLFGWERPMLSRIQEKRSFEVNNMYSLTLFDIIFKSGMKI 497

  Fly   323 SP-LSVFLALCSYV-YLGDPLTAQKVYTVSSYFNMLNDSMVTFWPMSITFIAEALVSAKRCKDFL 385
            :| :|:|:....|. .:|..||....:|..|.|.:|....:....:|..|| :..||.||..:|
pombe   498 APFISMFITFAIYTKIMGHQLTPATAFTSISMFGLLRYQFIWLASVSRQFI-QFKVSLKRVDNF- 560

  Fly   386 LDGDKAEVPINLEANQQTGKNKRKISKKDKQKNVELNGSLLSNGQVHHNRLRDYDPEATKKCVVL 450
                                                         |:.|.:.|...|::.. .|.
pombe   561 ---------------------------------------------VYGNMVNDSSIESSDS-FVF 579

  Fly   451 KNVSASWDTSDGHANCAIEDFSTDIKDQTLAAVVGPVGAGKSSFLNVLLGEVGIDKGE---AMVH 512
            :|.|.||..:...|...:::.:..|.......|||..|:|||:....||||:.:..|:   ..:.
pombe   580 ENTSLSWSPTPSTALFQLKNLNFTIPRNQFTLVVGSTGSGKSTLAMALLGELHVISGKMTTPSIS 644

  Fly   513 GKISYASQESWVFEGTIRDNIVFVEDYNERRYKKVVKVCGLERDMELLPRGDLTVVGERGVSLSG 577
            .:|:|..|.:|:..||||.||:|.|.|:|.||.:::|.|.|:.|:..:..||||.:...|.||||
pombe   645 QRIAYVPQAAWLRNGTIRSNILFGEPYDEERYFQIIKACCLDSDLNSMNDGDLTYIHSNGSSLSG 709

  Fly   578 GQKARVSLARAVYRKADIYLLDDPLSAVDTHVGKHIFDRC-IRDFLSNKIRILVTHQVQYLFDV- 640
            |||.|||||||:|..|::|:.||..||:|....:.|::.| :...|.:|..||.||.|.....:
pombe   710 GQKQRVSLARALYSNAEVYIFDDIFSALDVSTSRKIYESCFLSTLLQHKTIILFTHNVSLCLPIA 774

  Fly   641 EHLLLM--GSGKIMAQGSYQELQRSRQFQFLEQTQHD---ESGIDTHSV---SSYLSRSDSEKSM 697
            |:::::  .:.::::..|.|||..|..|.  ..|:.|   |..::.||.   |:..|.||:::..
pombe   775 ENVIVLKNSTAQLVSPDSIQELVPSTFFS--SNTKKDNIEEENLEPHSFSFDSTLASSSDNDEQR 837

  Fly   698 EHQHNQLLRPDEHVEDVNQEQQTVGSIKMHVYASYIKALDST-FLLGIVISLFVCARIMLTGVDY 761
            :...|                .::..:.:|    |:|...|. ::||.:: |.:.:::.|..:.:
pombe   838 DFASN----------------SSIVLLGLH----YLKYFGSNKYILGSIL-LVMMSQVSLASIHF 881

  Fly   762 FLSRWVIWEEQIAVNRTTTLLNETDTTIANDTLPINATDPYIAPLLASDIQAGIRQELVLFYATI 826
            :::.|                  :..::.:..||.:.:                   .:..||.:
pombe   882 WIALW------------------SGNSLFSLKLPSSFS-------------------FLWGYAIL 909

  Fly   827 LGATLIVYLIRTFGFFKMCLRISLHLHDRLFRGITRASMYFFNTNSSGRILNRFSKDIRTVD--- 888
            |....::.|.|...|.|.....|.::||.|...:..:.:::|...::||||||||||:...|
pombe   910 LFIYFLMDLSRAITFAKGGRTASENIHDILSERVLYSPLHWFEKTAAGRILNRFSKDMYATDNLL 974

  Fly   889 -TDLPHTLLDCLAFIIDVSGVVIIVAIANYWLLIPAAIIGVILGMIRYLYVNTSRSVKRLESISR 952
             ..|...||..:|.:|.:..|.:::.|    .::|||.:.:::.:..|.|....:.:..|:|...
pombe   975 WASLEGMLLCVMAILITMLNVTLVMPI----FMVPAAFVSLLVYLHGYAYSKAQKQLTSLQSSRT 1035

  Fly   953 SPVFSLTNQTFQGLTTIRALQAQSALEQEFHEYQNTNTSAWFLFLSCTRAFALWSDVLCIVYMTA 1017
            ||||::..:|..|:|.|||.:     :::..|::|               .|...|::..:|::.
pombe  1036 SPVFTMLGETLGGITVIRAFK-----KEKIFEHEN---------------MAFIDDMIQPLYISF 1080

  Fly  1018 VTFSFLLLKDEFDSGDVG-----LAILHSTTMTGMCQWGM--------------RQTAELENQMT 1063
            ....:|.::.:..||.||     :|:|......|:..:.:              |...|:...:.
pombe  1081 AINRWLAIRTDGISGLVGFSTGLIALLRQNIPPGLVGFSLNSAIGFNISVLVFVRANNEILTYIN 1145

  Fly  1064 SVERVLEYTEQPSEALLETPEKFKP-KSEWPSKGRIEFINFKLRYSPKEAPVLKDLNFTIEPREK 1127
            :..|:.||...|||. .|:....|| ..|||:.|.:...|..:.||..:|.||:|:|..|.|:||
pombe  1146 NFRRLYEYMLLPSEK-NESSCLTKPMNKEWPTLGHVSIKNLTVSYSIGQAAVLEDINLEILPKEK 1209

  Fly  1128 IGIVGRTGAGKSSIIQSIFRLA-CNEGMIRIDDVDIEHIGLHDLRSQVSIIPQDPVLFSGTLRYN 1191
            |.||||||:|||::..::.|.. ...|.:.:|.:||..:.|..||.::|:|||||||.|||:|.|
pombe  1210 IAIVGRTGSGKSTMGLTLLRFTMIMSGAVEVDGIDINSLDLEVLRQRISLIPQDPVLISGTVRSN 1274

  Fly  1192 LDPMDERSDEEMWKALGDVELRSYVSTLIGGLNCRMYD------------GGSNFSVGQRQLVCL 1244
            |||.:|..|.|    |.::...:...:|:...|....|            ||.|||.||||::.|
pombe  1275 LDPFEEYGDGE----LNEILKTASCESLVQASNKNSLDAFAIHLDTPVDSGGVNFSSGQRQILAL 1335

  Fly  1245 ARAILRHNKILIMDEATANVDPETDKLIQQTIRSKFAHCTVLTIAHRLHTVMDSDRVLVMDAGEV 1309
            |||::|.::|:|:||:||:||..||:.|||.:|:.|.|.|||.||||:.|::|.|:|||:|:|:.
pombe  1336 ARALVRKSRIVILDESTASVDDTTDRRIQQMLRAAFKHATVLCIAHRIKTIVDYDKVLVLDSGKT 1400

  Fly  1310 RELGHPYEL 1318
            .|.|.|..|
pombe  1401 VEFGSPKSL 1409

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rdog	NP_651678.1	MRP_assoc_pro	14..1323	CDD:188098	367/1367 (27%)
abc1	NP_594585.1	MRP_assoc_pro	166..1423	CDD:188098	371/1374 (27%)