Protein Alignment rdog and mrp-7

DIOPT Version :10

• Sequence 1: NP_651678.1
• Gene: rdog / 43450
• FlyBaseID: FBgn0039644
• Length: 1374
• Species: Drosophila melanogaster
• Sequence 2: NP_507812.3
• Gene: mrp-7 / 180289
• WormBaseID: WBGene00003413
• Length: 1525
• Species: Caenorhabditis elegans
• Alignment Length: 1435
• Identity: 454/1435 - (31%)
• Similarity: 719/1435 - (50%)
• Gaps: 220/1435 - (15%)

  Fly    13 NPFTKANFFSQWSFWWMRDLFKRGLQGPLTDEELYQHRKTLDSERVTNKFAELWED--ELKRSN- 74
            :|..:::|.::.:.||...:...|.:..|..:::::    |:....|...:||||.  |.||..
 Worm   207 SPELQSSFLNRLTLWWFNSIPWTGARRDLEIDDIFE----LNERSGTEFLSELWESFWEPKRLKY 267

  Fly    75 ----------------------PSVVRMILRAYGKIFVPMGLAFSISETICKSLMPLFLGGLVGY 117
                                  ||||..:...:...|:.......:|:|: :...|..|..|:.:
 Worm   268 IHDTSIWAKKDPSEQEKDPVVIPSVVSSLFMMFRWEFLLASTLKFVSDTM-QFASPFLLHELLNF 331

  Fly   118 FATNQTDISENTAYLYAMGIVICML----VPVITFHPFIFYIFQVGTKLRLALSGLIYRKVLQVS 178
            .:      ::|..:...|.:.|.|.    :..:..:.:.:.:|::|||::.:|:..:|:|.|.:|
 Worm   332 IS------AKNAPFWKGMALSILMFSVSELRSLILNGYFYIMFRMGTKIQTSLTAAVYKKTLLIS 390

  Fly   179 KSSSNDGLRGRAINILSNDLGRFDVALCFLHDTWKGPMESILIGFLMYREIGISAVIGVSFMLSF 243
            .|:..|...|..:|:::.|:.||.:....:...|..|.:.......::..:|.||:.||..|:.|
 Worm   391 NSARRDRTVGEIVNLMAIDVERFQMITPQIQQFWSCPYQITFALVYLFITLGYSALPGVVIMVIF 455

  Fly   244 IPLQAWAAKKAAYYRQMTAERTDMRVKLMNEIIQGIQVIKMYAWEKSFARVIAEVRLKEVKAIRG 308
            :|:...::.....::....:..|.|.|::||::.||:|:|:||||......|.|:|.||:..|:.
 Worm   456 VPMNIISSMIVRKWQIEQMKLKDERTKMVNEVLNGIKVVKLYAWEVPMEAYIDEIRTKELALIKK 520

  Fly   309 TAYIHAALGCTSMISPLSVFLALCSYVYLGDP---LTAQKVYTVSSYFNMLNDSMVTFWPMSITF 370
            :|.:...|...:..||..|.|.......|.:|   ||.|..:...:.||.|...| |...:.|..
 Worm   521 SAMVRNILDSFNTASPFLVALFSFGTFVLSNPSHLLTPQIAFVSLALFNQLRSPM-TMIALLINQ 584

  Fly   371 IAEALVSAKRCKDFLLDGDKAEVPINLEANQQTGKNKRKISKK--DKQKNVELNGSLLSNGQVHH 433
            ..:|:||.||.|:||:    ||                ::.:|  |:..|:|.:          |
 Worm   585 AVQAVVSNKRLKEFLV----AE----------------ELDEKCVDRSVNIERS----------H 619

  Fly   434 NRLRDYDPEATKKCVVLKNVSASWDTSDGHANCAIEDFSTDIKDQTLAAVVGPVGAGKSSFLNVL 498
            |.:|            ::|::||||..:......::|........:|.||||.||:||||.|..|
 Worm   620 NAVR------------VENLTASWDPEEAAGEKTLQDVDLTAPRNSLIAVVGKVGSGKSSLLQAL 672

  Fly   499 LGEVGIDKGEAMVHGKISYASQESWVFEGTIRDNIVFVEDYNERRYKKVVKVCGLERDMELLPRG 563
            |||:|..:|...|:|:::|..|:.|:...|:||||.|...::.:||.:|:..|.|:.|:::||.|
 Worm   673 LGEMGKLRGRIGVNGRVAYVPQQPWIQNMTLRDNITFGRPFDRKRYDQVLYACALKADIKILPAG 737

  Fly   564 DLTVVGERGVSLSGGQKARVSLARAVYRKADIYLLDDPLSAVDTHVGKHIFDRCI--RDFLSNKI 626
            |.|.:||:|::||||||||||||||||:..|:|||||||||||.|||:|||::.|  ...|..|.
 Worm   738 DQTEIGEKGINLSGGQKARVSLARAVYQNLDVYLLDDPLSAVDAHVGRHIFEKVIGPNGLLREKT 802

  Fly   627 RILVTHQVQYLFDVEHLLLMGSGKIMAQGSYQEL--QRSRQFQFLEQTQHDESGIDTHS------ 683
            ||||||.:.|....:.:|:|..|||...|:::.|  :|...|.|:|:.   :||.|..|
 Worm   803 RILVTHGLTYTKMADEILVMLEGKIEESGTFEHLIKRRGLFFDFMEEY---KSGSDNSSEAGGSQ 864

  Fly   684 ----------VSSYLSRSDSEKSMEHQHNQLLRPDEHVEDVN----------------------- 715
                      :..|::..|...::.:..::.:|..|....::
 Worm   865 DDDFEAIGGEIQDYMNPEDVVLTVTNDLDETIRTPELTTQISTMSSPEKPPTGTSPAAATESQNK 929

  Fly   716 ---QEQQTVGSIKMHVYASYIKALDSTFLLGIV-ISLFVCARIMLTGVDYFLSRWVIWEEQIAVN 776
               :|....|.:::..|..|:||  :.:||.|. |..|:....:.....::||.|
 Worm   930 LIKKEGIAQGKVEIATYQLYVKA--AGYLLSIAFIGFFIVYMTLQILRSFWLSAW---------- 982

  Fly   777 RTTTLLNETDTTIANDTLPINATDPYIAPLLASDIQAGIR-----QELVLFYATILGATLIVYLI 836
                 .:|.|            .|...|..:|...:.|:.     .|...|:..:|....:..
 Worm   983 -----SDEYD------------PDSPSAHPMAKGWRLGVYGALGFSETACFFVALLALVFVGQ-- 1028

  Fly   837 RTFGFFKMCLRISLHLHDRLFRGITRASMYFFNTNSSGRILNRFSKDIRTVDTDLPHTLLDCLAF 901
                      |.|.:||..|...:.|:.|.|::|...||||||.:|||.|:|..||......:..
 Worm  1029 ----------RASKNLHGPLIHNLMRSPMSFYDTTPLGRILNRCAKDIETIDMMLPMNFRYLVMC 1083

  Fly   902 IIDVSGVVIIVAIAN---YWLLIPAAIIGVILGMIRYLYVNTSRSVKRLESISRSPVFSLTNQTF 963
            ::.|:..:|::.|:.   ..:::|.|:|.:|  .:|| ||.|||.:|||||:.|||::|...:|.
 Worm  1084 VLQVAFTLIVIIISTPLFAVVILPLALIYLI--FLRY-YVPTSRQLKRLESVHRSPIYSHFGETI 1145

  Fly   964 QGLTTIRALQAQSALEQEFHEYQNTNTSAWFLFLSCTRAFALWSDVL--CIVYMTAVTFSFLLLK 1026
            ||..:|||........|:.....:|.....:..|...|..|:..:.:  ||::..|:   |.:|.
 Worm  1146 QGAASIRAFGKVDEFRQDSGRILDTFIRCRYSSLVSNRWLAVRLEFVGNCIIFFAAL---FAVLS 1207

  Fly  1027 DEF----DSGDVGLAILHSTTMTGMCQWGMRQTAELENQMTSVERVLEYTEQPSEALLETP---E 1084
            .||    ..|.:|:::.::..:|.:..:.:||.:|:|..:.|||||.|||..|:||    |   |
 Worm  1208 KEFGWITSPGVIGVSVSYALNITEVLNFAVRQVSEIEANIVSVERVNEYTNTPNEA----PWRIE 1268

  Fly  1085 KFKPKSEWPSKGRIEFINFKLRYSPKEAPVLKDLNFTIEPREKIGIVGRTGAGKSSIIQSIFR-L 1148
            ..:|...|||:|.::|..:..||......||.|::..:...|||||||||||||||...::|| :
 Worm  1269 GREPAPGWPSRGVVKFDGYSTRYREGLDLVLHDISADVAAGEKIGIVGRTGAGKSSFALALFRMI 1333

  Fly  1149 ACNEGMIRIDDVDIEHIGLHDLRSQVSIIPQDPVLFSGTLRYNLDPMDERSDEEMWKALGDVELR 1213
            ....|.|.||||::..||||||||.::||||||||||||||:||||....||:::|:||....|:
 Worm  1334 EAAGGRIVIDDVEVSQIGLHDLRSNITIIPQDPVLFSGTLRFNLDPFFTYSDDQIWRALELAHLK 1398

  Fly  1214 SYVSTLIGGLNCRMYDGGSNFSVGQRQLVCLARAILRHNKILIMDEATANVDPETDKLIQQTIRS 1278
            .:.:.|..||..::.:.|.|.||||||||.||||:|||.::|::|||||.||..||.|||:|||.
 Worm  1399 HFAAGLPDGLLYKISEAGENLSVGQRQLVALARALLRHTRVLVLDEATAAVDVATDALIQETIRE 1463

  Fly  1279 KFAHCTVLTIAHRLHTVMDSDRVLVMDAGEVRELGHPYELL-QRTGGYLRQLVDNTGAATSFALQ 1342
            :|..|||.||||||:|:||.||::|:|.|.:.|...|..|: .:...:.:.:.|
 Worm  1464 EFKECTVFTIAHRLNTIMDYDRIMVLDKGSILEFDTPDALMADKNSAFAKMVAD----------- 1517

  Fly  1343 QAAEQ 1347
             ||||
 Worm  1518 -AAEQ 1521

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rdog	NP_651678.1	MRP_assoc_pro	14..1323	CDD:188098	449/1408 (32%)
mrp-7	NP_507812.3	MRP_assoc_pro	14..1518	CDD:188098	450/1430 (31%)