Protein Alignment rdog and haf-2

DIOPT Version :9

• Sequence 1: NP_651678.1
• Gene: rdog / 43450
• FlyBaseID: FBgn0039644
• Length: 1374
• Species: Drosophila melanogaster
• Sequence 2: NP_495537.2
• Gene: haf-2 / 174204
• WormBaseID: WBGene00001812
• Length: 773
• Species: Caenorhabditis elegans
• Alignment Length: 565
• Identity: 149/565 - (26%)
• Similarity: 263/565 - (46%)
• Gaps: 93/565 - (16%)

  Fly   811 IQAGIRQELVLFYATILGATLIVYLIRTFGFFK-----MCLRISLHLHDRLFRGITRASMYFFNT 870
            |||.|...:||   |.|.||..::.....|.|.     :.|||.|.    ||..:.|..:.|::|
 Worm   245 IQALIHSIIVL---TCLTATSSLFGGLRGGCFDYATALVTLRIRLD----LFTSLIRQDIAFYDT 302

  Fly   871 NSSGRILNRFSKDIRTVDTDLPHT----------LLDCLAFIIDVSGVVIIVAIANYWLLIPAAI 925
            ..:|..::|.:.|.:|:.:.:...          |:..|||:|.:|           |.|.....
 Worm   303 AKTGDTMSRLTSDCQTISSTVSTNVNVFMRNGVMLIGALAFMILMS-----------WRLAMVTF 356

  Fly   926 IGV-ILGMIRYLYVNTSRSVKRLESISRSPVFSLTNQTFQG-LTTIRALQAQSALEQEFHEYQNT 988
            |.| ::|.|...|  :|...|..|.:.::  .:.|||..:. ::|:|.:::.:..::|...:::.
 Worm   357 IAVPLVGFITKAY--SSFYDKISEKLQQT--IAETNQMAEEVVSTMRTVRSFACEKKELKRFEDR 417

  Fly   989 NTSAWFLFLSCTR------AFALWSDVLC-IVYMTAVTF--SFLLLKDEFDSGDVGLAILH---- 1040
            .:|.    ||..|      .|..|::..| ...:.||.|  ..|::..:.:...:...:|:
 Worm   418 LSST----LSVNRKKSIAYLFYTWNNEFCDNAILVAVLFYGGHLVMTGKMEKEQLITFLLYQMQL 478

  Fly  1041 -------STTMTGMCQ--WGMRQTAELENQMTSVERVLEYTEQPSEALLETPEKFKPKSEWPSKG 1096
                   |..|:|:.:  ...|:..:|.|:....|  |:..::|.                 ..|
 Worm   479 GENLYYLSYVMSGLMEAVGASRKVFDLMNRKPQFE--LDGMQRPF-----------------VNG 524

  Fly  1097 RIEFINFKLRY-SPKEAPVLKDLNFTIEPREKIGIVGRTGAGKSSIIQSIFRL-ACNEGMIRIDD 1159
            .|.|.:....| |....||||||..:|:..|.:.:||.:|.|||||:..|... ..:||.:.:|.
 Worm   525 NITFSHVGFTYPSRPNNPVLKDLTLSIKSGETVALVGPSGGGKSSIVSLIEHFYEPDEGSVTLDG 589

  Fly  1160 V---DIEHIGLHDLRSQVSIIPQDPVLFSGTLRYN-LDPMDERSDEEMWKALGDVELRSYVSTLI 1220
            |   ||.|:..|   .:|:::.|:|||::|::|:| |...|..::::|..|.....:..:|..|.
 Worm   590 VPIKDINHVYYH---QKVALVAQEPVLYNGSVRHNILYGCDFATEDDMLNASKMANVHDFVMELE 651

  Fly  1221 GGLNCRMYDGGSNFSVGQRQLVCLARAILRHNKILIMDEATANVDPETDKLIQQTIRSKFAHCTV 1285
            .|.:....:.|...|.||:|.:.:|||::|:..:||:||||:.:|.|::.|:||.:.......||
 Worm   652 KGYDTNCGEKGVQMSGGQKQRIAIARALVRNPAVLILDEATSALDTESEALVQQALSRCAQERTV 716

  Fly  1286 LTIAHRLHTVMDSDRVLVMDAGEVRELGHPYELLQRTGGYLRQLV 1330
            :.:||||.|:..::::.|:..|.:.::|...||:..|.|....||
 Worm   717 IIVAHRLSTIEKANKIAVIVKGCLVQMGTHTELMTDTDGMYYSLV 761

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rdog	NP_651678.1	CFTR_protein	12..1343	CDD:273530	149/565 (26%)
		ABC_membrane	94..360	CDD:294371
		ABCC_MRP_domain1	448..650	CDD:213217
		ABC_membrane	821..1046	CDD:294371	56/261 (21%)
		ABCC_MRP_domain2	1096..1315	CDD:213211	75/224 (33%)
haf-2	NP_495537.2	3a01208	15..761	CDD:273363	147/563 (26%)
		ABC_membrane	215..478	CDD:279056	59/258 (23%)
		ABC_MTABC3_MDL1_MDL2	526..764	CDD:213216	80/239 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000