Protein Alignment rdog and abcc9

DIOPT Version :10

• Sequence 1: NP_651678.1
• Gene: rdog / 43450
• FlyBaseID: FBgn0039644
• Length: 1374
• Species: Drosophila melanogaster
• Sequence 2: XP_031754288.1
• Gene: abcc9 / 101733439
• XenbaseID: XB-GENE-6074535
• Length: 1577
• Species: Xenopus tropicalis
• Alignment Length: 1432
• Identity: 422/1432 - (29%)
• Similarity: 712/1432 - (49%)
• Gaps: 203/1432 - (14%)

  Fly     9 VRPKNPFTKANFFSQWSFWWMRDLFKRGLQGPLTDEELYQHRKTLDSERV----------TN--K 61
            ||...||  .|..|:.::|||..|.            :..|::.:|.:.:          ||  .
 Frog   213 VRFLQPF--VNLLSKATYWWMNPLI------------ISAHKRPIDLKTIGKLPIAMRALTNYLS 263

  Fly    62 FAELWEDELKR------SNPSVVRMILRAYGKIFVPMGLAFSISETICKSLMPLFLGGLVG---- 116
            ....:|::.|:      .:||:.:.|.||:|:..: :...|.....:.....||.:.|:|.
 Frog   264 LKTAYEEQKKKLVDRPHKDPSIWKAIYRAFGRPIL-LSSTFRYLADLLGFAGPLCISGIVQLLDS 327

  Fly   117 ------------------YFATNQTDISENTAYLYAMGIVICM-LVPVITFHPFIFYI-FQVGTK 161
                              ||.::: .:.||   .|.:.:::.: |:...||....:|: .:.|..
 Frog   328 RNKGPTDQDFPKTNFSSVYFLSSK-GLIEN---YYVLAVLLFLALILQRTFLQASYYVTIETGIN 388

  Fly   162 LRLALSGLIYRKVLQVSKSSSNDG--LRGRAINILSNDLGRFDVALCFLHDTWKGPMESILIGFL 224
            ||.||..:||.|:|::|.|:.:.|  ..|:..|:::.:..:....|....:.|..|::.|:...|
 Frog   389 LRGALLSMIYNKILRLSTSNMSMGEMTLGQINNLVAIETNQLMWFLFLCPNLWAMPIQIIMGVIL 453

  Fly   225 MYREIGISAVIGVSFMLSFIPLQAWAAKKAAYYRQMTAERTDMRVKLMNEIIQGIQVIKMYAWEK 289
            :::.:|:||::|.:.::...|:|.:.|.|.|..::.|.:.:..|:|..|||::||:::|:||||.
 Frog   454 LHKLVGVSALVGAAVIVLLAPMQYFIATKLAEVQKNTLDYSTERLKKTNEILKGIKLLKLYAWEN 518

  Fly   290 SFARVIAEVRLKEVKAIRGTAYIHAALGC-TSMISPLSVFLA-LCSYVYLGDP-LTAQKVYTVSS 351
            .|...:.|.|:||:|::: |..:|.:|.. .:...|::..|| ..::.|:... ||....:...|
 Frog   519 IFCNSVEETRIKELKSLK-TFALHTSLSIFMNAAIPIAAVLATFVTHAYVSSSHLTPANAFASLS 582

  Fly   352 YFNMLNDSMVTFWPMS--ITFIAEALVSAKRCKDFLL------DGDK-AEVPINLEA-NQQTGKN 406
            .|::|   :...:.:|  :.|..:||||.::..:|..      ||.: .|..:..|: .:..|.:
 Frog   583 LFHIL---VTPLFLLSTVVRFAVKALVSVQKLNEFFTSDEIREDGFRNGETTLPFESCRKHPGIH 644

  Fly   407 KRKISKKDKQKNVELNGSLLSNGQVHHNRLRDYDPE--ATKKCVVLKNVSASWDTSDGHANCAIE 469
            .|..::|.     .|...:....|....::|..|.|  |.|.|    ....||.|  |.|..|
 Frog   645 SRAFNRKQ-----PLRYQMDKYDQAPKRQVRTSDTEDAALKVC----GGFFSWGT--GLATLA-- 696

  Fly   470 DFSTDIKDQT--LAAVVGPVGAGKSSFLNVLLGEVGIDKGEAM--------------VHG----- 513
              :.||:..|  |..:||.||.||||.|..:|||:...:|..:              .:|
 Frog   697 --NIDIQIPTGELTMIVGQVGCGKSSLLLAILGEMQTLEGRVVWNKFGSQRRAPGSSANGWDSAC 759

  Fly   514 ---------KISYASQESWVFEGTIRDNIVFVEDYNERRYKKVVKVCGLERDMELLPRGDLTVVG 569
                     .::||.|:.|:...|:.:||.|...:|::|||.|...|.|:.|::|||.||.|.:|
 Frog   760 GSERSKNRHSVAYAGQKPWLLNATLEENITFGSPFNKQRYKAVTDACSLQPDIDLLPFGDQTEIG 824

  Fly   570 ERGVSLSGGQKARVSLARAVYRKADIYLLDDPLSAVDTHVGKHIFDRCIRDFLSNKIR--ILVTH 632
            |||::|||||:.|:.:|||:|:..:|..||||.||:|.|:..|:....|..||....|  :||||
 Frog   825 ERGINLSGGQRQRICVARALYQNTNIVFLDDPFSALDIHLSDHLMQEGILKFLREDKRTVVLVTH 889

  Fly   633 QVQYLFDVEHLLLMGSGKIMAQGSYQELQRS-----RQFQFLEQTQHDESGIDTHSVSSYLSRSD 692
            ::|||...:.::.|..|.::.:|:.:::|.:     ..::.|...|..|...|:.:....:.|..
 Frog   890 KLQYLPHADWIIAMKDGSVLREGTLKDIQNNDNELYEHWKTLMNRQDQELEKDSDADQVTMERKT 954

  Fly   693 SEKSMEHQHNQLLRPDEHVEDVNQEQQTVGSIKMHVYASY-----IKALDSTFLLGIVISLF--V 750
            ..::|..:..::...:|..|:..:::....|..|.:...:     .:.|.|...|.:.:.:|  :
 Frog   955 LRRAMYSREAKVQAEEEEEEEEEEDEDETMSTAMRLRTKFPWRTCWRYLTSGGYLLLFLMIFSKL 1019

  Fly   751 CARIMLTGVDYFLSRWVIWEEQIAVNRTTTLLNETDTTIANDTLPINATDPYIAPLLASDIQAGI 815
            ....::..:||:|:.|......|:..::..:.:.::                     .|.||:
 Frog  1020 LKHSVIVAIDYWLASWTSETSNISYAQSDNVTSASE---------------------LSSIQS-- 1061

  Fly   816 RQELVLFYAT---ILGAT-LIVYLIRTFGFFKMCLRISLHLHDRLFRGITRASMYFFNTNSSGRI 876
                  :|.|   :|.|| :::.||.:.....|.|..:.:||..|.:.|..|.:.||:|...|.|
 Frog  1062 ------YYVTGFSVLSATGIVLCLIASLTVEWMGLNAAKNLHHNLLKKIILAPIRFFDTTPLGLI 1120

  Fly   877 LNRFSKDIRTVDTDLPHTL-------LDCLAFIIDVSGVVIIVAIANYWLLIPAAIIGVILGMIR 934
            |||||.|...:|..:|.||       |.||:.|    ||:......:...|:|   :||....|:
 Frog  1121 LNRFSADTNIIDQHIPPTLESLTRSTLLCLSAI----GVISYATPISMVALLP---LGVAFYFIQ 1178

  Fly   935 YLYVNTSRSVKRLESISRSPVFSLTNQTFQGLTTIRALQAQSALEQEFHEYQNTNTSAWFLFLSC 999
            ..:...|:.::.|:..::.|:....::|.:|||||||.:.::..:|...|..:||..| :||||.
 Frog  1179 KYFRVASKDLQELDDSTQLPLLCHFSETAEGLTTIRAFRHEARFKQRMLELTDTNNLA-YLFLSA 1242

  Fly  1000 TRAFALWSDV------LCIVYMTAVTFSFLLLKDEFDSGDVGLAILHSTTMTGMCQWGMRQTAEL 1058
            ...   |.:|      .||| :||..||   :....|||.|||.:.::.|:|....|.:|..|:|
 Frog  1243 ANR---WLEVRTDYLGACIV-LTAAVFS---ITYGLDSGIVGLGLTYALTVTNYLNWVVRNLADL 1300

  Fly  1059 ENQMTSVERVLEYTEQPSEALLETPEKFKPKSEWPSKGRIEFINFKLRYSPKEAPVLKDLNFTIE 1123
            |.|:.:|::|..:....||....:.|:.:...:||..|.|...:..:||.....||||.|...|:
 Frog  1301 EVQIGAVKKVNSFLNIESECYEGSMEQQQVPEDWPQSGEIRISDLCVRYENNHKPVLKHLKAYIK 1365

  Fly  1124 PREKIGIVGRTGAGKSSIIQSIFRLA-CNEGMIRIDDVDIEHIGLHDLRSQVSIIPQDPVLFSGT 1187
            |.:|:||.||||:||||:..:.||:. ..:|.|.||.:||..:.|:.|||::|||.|||:||||:
 Frog  1366 PGQKVGICGRTGSGKSSLSLAFFRMVDIFDGKIVIDGIDISKLPLNTLRSRLSIILQDPILFSGS 1430

  Fly  1188 LRYNLDPMDERSDEEMWKALGDVELRSYVSTLIGGLNCRMYDGGSNFSVGQRQLVCLARAILRHN 1252
            :|:||||..:.|||.:|:.|...:|::.|..|.|||:..:.:||.|||||||||.|||||.:|::
 Frog  1431 IRFNLDPECKCSDERLWEGLDIAQLKNLVKALPGGLDAMVTEGGENFSVGQRQLFCLARAFVRNS 1495

  Fly  1253 KILIMDEATANVDPETDKLIQQTIRSKFAHCTVLTIAHRLHTVMDSDRVLVMDAGEVRELGHPYE 1317
            .|||||||||::|..|:.::|:.:.:.||..||:|||||:||::..|..:||..|.:.|...|..
 Frog  1496 SILIMDEATASIDMATENILQKVVMTAFADRTVVTIAHRVHTILTGDVAIVMRRGNILEHDTPGN 1560

  Fly  1318 LL 1319
            ||
 Frog  1561 LL 1562

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rdog	NP_651678.1	MRP_assoc_pro	14..1323	CDD:188098	420/1427 (29%)
abcc9	XP_031754288.1	MRP_assoc_pro	222..1574	CDD:188098	417/1421 (29%)