Protein Alignment rdog and LOC100493583

DIOPT Version :10

• Sequence 1: NP_651678.1
• Gene: rdog / 43450
• FlyBaseID: FBgn0039644
• Length: 1374
• Species: Drosophila melanogaster
• Sequence 2: XP_031752469.1
• Gene: LOC100493583 / 100493583
• XenbaseID: XB-GENE-29081803
• Length: 1289
• Species: Xenopus tropicalis
• Alignment Length: 1358
• Identity: 449/1358 - (33%)
• Similarity: 712/1358 - (52%)
• Gaps: 145/1358 - (10%)

  Fly    13 NPFTKANFFSQWSFWWMRDLFKRGLQGPLTDEELYQHRKTLDSERVTNKFAELWEDELKR----- 72
            ||...|:..|:.::.|...:...|.:.||..|:|::......|..|...|.:.|.:|:.|
 Frog    23 NPEKNASLLSRLTYSWYSRIITLGYKKPLEREDLFELNDNDSSYTVIPIFEKNWRNEVARQAQKG 87

  Fly    73 ---SNPSVVR---------MILRAYGKIFVPMGLAFSISETICKSLMPLFLGGLVGYFATNQTDI 125
               .|.|::|         :|..|:.|:...: ||||         .|..|..::.:  |.:...
 Frog    88 TVSKNVSLLRALWNTFKYSLIQVAFMKVIADI-LAFS---------SPQILKRMIAF--TEERPD 140

  Fly   126 SENTAYLYAMGIVICMLVPVITFHPFIFYIFQ-----VGTKLRLALSGLIYRKVLQVSKSSSNDG 185
            ...|.|..|:     :|:.|......|..::|     ...|::.::.||||||.||::.||....
 Frog   141 EGWTGYALAL-----LLLVVTVSQTLILQLYQRFNMLAAVKMKTSVIGLIYRKALQLAYSSRKKF 200

  Fly   186 LRGRAINILSNDLGRFDVALCFLHDTWKGPMESILIGFLMYREIGISAVIGVSFMLSFIPLQAWA 250
            ..|..:|::|:|..:.......|:..|..|.:.::....:::|:|.|.:.||..::..||:.|:.
 Frog   201 TTGELVNLMSSDAQQLMDLTVNLNLLWSAPFQILMAVVFLWQELGASVLAGVGVLILVIPINAFI 265

  Fly   251 AKKAAYYRQMTAERTDMRVKLMNEIIQGIQVIKMYAWEKSFARVIAEVRLKEVKAIRGTAYIHAA 315
            |.:....::...:..|.|:||:|||:.||:::|:||||.|:.|.:|::|..|:..::.:.|:...
 Frog   266 ASRVKQLKKSHLKSKDQRIKLLNEILHGIKILKLYAWEPSYQRKVADIRESEMDVLKSSGYLTTF 330

  Fly   316 LGCTSMISPLSVFLALCSYVYLGDP---LTAQKVYTVSSYFNMLNDSMVTFWPMSITFIAEALVS 377
            ...|....|..|.:|.....:|.|.   |||.||:|..|.||:|...:... |..|:.:.:..||
 Frog   331 SMLTLTCIPFLVSMATFGVYFLLDDANVLTASKVFTTISLFNILRLPLFDL-PTVISSVVQTRVS 394

  Fly   378 AKRCKDFLLDGDKAEVPINLEANQQTGKNKRKISKKDKQKNVE--LNGSLLSNGQVHHNRLRDYD 440
            ..|.::|.. |::    ||.|                   |:|  .:||
 Frog   395 LGRLENFFC-GEE----INTE-------------------NIETKYSGS---------------- 419

  Fly   441 PEATKKCVVLKNVSASWDTSDGHANCAIEDFSTDIKDQTLAAVVGPVGAGKSSFLNVLLGEVGID 505
                 ..|.....|..||.:   ....::|....|.:.:|.||||.||:||||.|:.:|||:...
 Frog   420 -----HAVGFSGASFQWDKT---GPSILKDLDFKIPEGSLVAVVGQVGSGKSSLLSAILGEMNTL 476

  Fly   506 KGEAMVHGKISYASQESWVFEGTIRDNIVFVEDYNERRYKKVVKVCGLERDMELLPRGDLTVVGE 570
            :|:....|.::|.||::|:.....::||:|...:|::.|::|::.|.|..|:||||.||.|.:||
 Frog   477 EGKVQRKGAVAYVSQQAWIQNALFQENILFGLAFNKQHYERVLEACALLPDLELLPNGDQTEIGE 541

  Fly   571 RGVSLSGGQKARVSLARAVYRKADIYLLDDPLSAVDTHVGKHIFDRCI--RDFLSNKIRILVTHQ 633
            |||:||||||.|||||||||..||||||||||||||.|||||:||:.|  :..:.||.|:||||.
 Frog   542 RGVNLSGGQKQRVSLARAVYSNADIYLLDDPLSAVDVHVGKHLFDKLIGPKGLIKNKTRVLVTHS 606

  Fly   634 VQYLFDVEHLLLMGSGKIMAQGSYQELQRSRQFQFLEQTQHDESGIDTHSVSSYLSRSDSEKSME 698
            :..|...:.:::|..|:....|:||||...|| .|.:..|....|.:...:|.........|:::
 Frog   607 LTVLPQTDLIIVMEEGRAAHIGTYQELMSKRQ-NFADMIQTFNKGTENEQLSDTAGVFRDPKALQ 670

  Fly   699 HQHNQ----LLRPDEHVEDVN------QEQQTVGSIKMHVYASYIKALDSTFLLGIVISLFVCAR 753
            ...:|    .::.|..:.:::      :|:...|:::|.:...|:.|...:::...||: ::...
 Frog   671 RTKSQHEDGFIKKDRTLTEMSKMPSMKKEKVATGNMRMSIVMKYLYAFGWSWVWFTVIA-YIGQN 734

  Fly   754 IMLTGVDYFLSRWVIWEEQIAVNRTTTLLNETDTTIANDTLPINATDPYIAPLLASDIQAGIRQE 818
            .:..|.:.:||||.  .|...:..|:..     |.:.|:.|.|..       ||      |..|.
 Frog   735 ALAVGQNVWLSRWA--TEAKGIRETSEW-----TELRNNRLGIYG-------LL------GFVQG 779

  Fly   819 LVLFYATILGATLIVYLIRTFGFFKMCLRISLHLHDRLFRGITRASMYFFNTNSSGRILNRFSKD 883
            :::.|    ||.::     |.|  .:|  .|..||:::...:....:.||.|...|::||||:||
 Frog   780 ILVCY----GAYVV-----TRG--TIC--ASRLLHNQMLDNVLHLPLQFFETTPMGQLLNRFTKD 831

  Fly   884 IRTVDTDLPHTLLDCLAFIIDVSGVVIIVAIANYWLLIPAAIIGVILGMIRYLYVNTSRSVKRLE 948
            :..:|....:.|...|..::||.|.:|::..|....::....:|.:..:|:..|:::||.::||:
 Frog   832 VYVIDERFHYYLRTWLNCMLDVLGTIIVIVYATPIFILAVVPLGFLYLLIQRYYISSSRQIRRLD 896

  Fly   949 SISRSPVFSLTNQTFQGLTTIRALQAQSALEQEFHEYQNTNTSAWFLFLSCTRAFALWSDVL-CI 1012
            ..|||||.|...:|..|..||||...|.....:..:..|.|...::..:...|..|:..:.| .:
 Frog   897 GASRSPVISHFGETLMGAPTIRAYGHQERFINQNKDVVNENLVCYYNNVISNRWLAVRLEFLGSL 961

  Fly  1013 VYMTAVTFSFLLLKDEFDSGDVGLAILHSTTMTGMCQWGMRQTAELENQMTSVERVLEYTEQPSE 1077
            :...|..|: :...|:.:||.|||:|.::..:|....:.:|:..|:|....::||:.||.|...|
 Frog   962 MIFFAALFA-VQAGDKMNSGIVGLSITYALNITQTLNFWVRKACEIETNGVAIERICEYEEMQKE 1025

  Fly  1078 ALLETPEKFKPKSEWPSKGRIEFINFKLRYSPKEAPVLKDLNFTIEPREKIGIVGRTGAGKSSII 1142
            |.....:  :|...||.:|.|||:|:|.||.......|:|:.|.:...||:|||||||||||::.
 Frog  1026 APWIMGK--RPPVRWPDQGIIEFVNYKARYREDHDLALQDITFRLHATEKLGIVGRTGAGKSTLT 1088

  Fly  1143 QSIFR-LACNEGMIRIDDVDIEHIGLHDLRSQVSIIPQDPVLFSGTLRYNLDPMDERSDEEMWKA 1206
            ..:|| :....|.|.||.:||..||||||||:::|||||||||||||:.||||:::.||.|:|:|
 Frog  1089 NCLFRTVEGTGGKIIIDGIDIATIGLHDLRSKLNIIPQDPVLFSGTLQMNLDPLEQHSDAELWEA 1153

  Fly  1207 LGDVELRSYVSTLIGGLNCRMYDGGSNFSVGQRQLVCLARAILRHNKILIMDEATANVDPETDKL 1271
            |....|:.:|.:|...|...:.:||.|.|||||||:|||||:||..|||::|||||::|.|||.|
 Frog  1154 LELCHLKPFVMSLPKRLYHDISEGGENLSVGQRQLICLARALLRKAKILVLDEATASIDMETDNL 1218

  Fly  1272 IQQTIRSKFAHCTVLTIAHRLHTVMDSDRVLVMDAGEVRELGHPYELLQRTGGYLRQL 1329
            :|.|||..|:.|||||||||||:|:||:||||:|||.|.|.|.|..|:::.|.:.|.:
 Frog  1219 VQATIRKAFSDCTVLTIAHRLHSVLDSERVLVLDAGRVVEFGEPQRLIEKKGYFSRMI 1276

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rdog	NP_651678.1	MRP_assoc_pro	14..1323	CDD:188098	446/1349 (33%)
LOC100493583	XP_031752469.1	MRP_assoc_pro	24..1279	CDD:188098	448/1357 (33%)