Protein Alignment rdog and abcc10

DIOPT Version :10

• Sequence 1: NP_651678.1
• Gene: rdog / 43450
• FlyBaseID: FBgn0039644
• Length: 1374
• Species: Drosophila melanogaster
• Sequence 2: NP_001135594.1
• Gene: abcc10 / 100216149
• XenbaseID: XB-GENE-6465377
• Length: 1501
• Species: Xenopus tropicalis
• Alignment Length: 1348
• Identity: 435/1348 - (32%)
• Similarity: 711/1348 - (52%)
• Gaps: 116/1348 - (8%)

  Fly    19 NFFSQWSFWWMRDLFKRGLQGPLT---DEELYQHRKTLDSERVTNKFAELWEDELKRSNPSVVRM 80
            ::.|::.:.|:..|.::|.:|.|.   |..|..|  .|.:.|:...|.       .:|:.:::|:
 Frog   229 SWLSRFFYLWLNPLLRQGARGGLKHPGDVLLLPH--CLGTARICQHFQ-------SKSSSTILRL 284

  Fly    81 I--LRA-YGKIFVPMGLAFSISETICKSLMPLFLGGLVGYFATNQTDISENTAYLYAMGIVICML 142
            :  |.| :|..:..:|| ..:.......|.||.|..||.:.......:|  ...||.:|:.....
 Frog   285 LPTLHASFGARYYALGL-LKLGAVTLAFLGPLLLNLLVNFMEAADEPLS--WGILYTLGLFSSCF 346

  Fly   143 VPVITFHPFIFYIFQVGTKLRLALSGLIYRKVLQVSKSSSNDGLRGRAINILSNDLGRFDVALCF 207
            :..:..:.|...:.::...:|.::...:|||.::...:......:|..:|.:|.|..|.......
 Frog   347 LAALLQNQFTHEVNKLILAVRASVLTSVYRKAIRGVGTGLAGFSKGEIVNFMSTDADRISNFCRS 411

  Fly   208 LHDTWKGPMESILIGFLMYREIGISAVIGVSFMLSFIPLQAWAAKKAAYYRQMTAERTDMRVKLM 272
            .|:.|..|::..:..:|:|.::||:.:.|:...:..:|:....|.:...|........|.|||||
 Frog   412 FHEVWSLPLQFSVTLYLLYLQVGIAFLGGLGLAVLLLPINKVIANRIVDYNSDLLNHKDARVKLM 476

  Fly   273 NEIIQGIQVIKMYAWEKSFARVIAEVRLKEVKAIRGTAYIHAALGCTSMISPLSVFLAL---CSY 334
            .|::.|::|:|.|.|||.||..:..:|.||::::|....:.|.  |..:.:.|.|.:::   .:|
 Frog   477 TELLSGMRVVKFYTWEKHFAEAVTSLREKELRSLRALKMLDAV--CVYLWAALPVLISIITFITY 539

  Fly   335 VYLGDPLTAQKVYTVSSYFNMLNDSMVTFWPMSITFIAEALVSAKRCKDFLLDGDKAEVPINLEA 399
            |.||..|||.||:|..:...||...:..| |..:..:.||.||.:|.:.|:      ::|
 Frog   540 VLLGHQLTAAKVFTALALVGMLILPLNNF-PWVLNGVLEAKVSLERIQLFM------DLP----- 592

  Fly   400 NQQTGKNKRKISKKDKQKNVELNGSLLSNGQVHHNRLRDYDPEATKKCVVLKNVSASW---DTSD 461
                        ::|          ||:    ::::....||.:   .:.|::.:.||   ::.|
 Frog   593 ------------EQD----------LLN----YYSQEPPADPSS---ALELRSAAFSWMPEESED 628

  Fly   462 -GHANCAIEDFSTDIKDQTLAAVVGPVGAGKSSFLNVLLGEVGIDKGEAMV-HGKI--SYASQES 522
             |.....||..|  ::...|..|||.||.||||.|..|.||:....||... |.::  .:|:||.
 Frog   629 SGSLQLFIEHLS--VQKGVLVGVVGKVGCGKSSLLAALTGELSRSGGELFASHQELGFGFAAQEP 691

  Fly   523 WVFEGTIRDNIVFVEDYNERRYKKVVKVCGLERDMELLPRGDLTVVGERGVSLSGGQKARVSLAR 587
            |:...|||:||:|.:::|.:.|:.|::.|.|..|:.:||.||.|.|||.||:||||||||::|||
 Frog   692 WIQFATIRENILFGKEFNGKLYQGVLEACALNDDLSILPSGDQTEVGENGVTLSGGQKARLALAR 756

  Fly   588 AVYRKADIYLLDDPLSAVDTHVGKHIFDRCIRDFLSNKIRILVTHQVQYLFDVEHLLLMGSGKIM 652
            |||:..|||||||||:|||..|..|:.::||...|.||.|||.||:.:.|...:.:|||..||::
 Frog   757 AVYQDKDIYLLDDPLAAVDADVAAHLMEKCILGILKNKTRILCTHRTELLDKADIVLLMEGGKMV 821

  Fly   653 AQGSYQEL----QRSRQFQFLEQTQHDESGIDTHSVSSYLSRSDSEKSMEHQHNQLLRPDEHVED 713
            ..|:..::    :.||......|||     ::..|.::..|..:.|:..|::.|.:   .....:
 Frog   822 GSGTPDKILPLVESSRNRGSRGQTQ-----MNHISQAAEQSLEEDEEEAENEGNPI---QPITAE 878

  Fly   714 VNQEQQTVGSIKMHVYASYIKALDSTFLLGIVISLFV--CARIMLTGVDYFLSRWVIWEEQIAVN 776
            |.||::..|::.:.||.:|.||:.......::::||:  .:|.:   .|::||.|:...:...
 Frog   879 VGQEEKQEGAVALQVYWAYWKAVGGCLAGSVLLALFLMQASRNI---SDWWLSHWISSLQDSP-- 938

  Fly   777 RTTTLLNETDTTIANDTLPINATDPYIAPLLASDIQAGIRQEL--VLFYATILG----ATLIVYL 835
            |..:|.|.|.::..:.:|.:.:....::|:  |.:.:..:...  :.||.::.|    |..|...
 Frog   939 RNVSLTNLTPSSFPSASLLLFSQGGLVSPI--SSVHSAEKNSSLDITFYLSVYGGIAVANSIFTA 1001

  Fly   836 IRTFGFFKMCLRISLHLHDRLFRGITRASMYFFNTNSSGRILNRFSKDIRTVDTDLPHTLLDCLA 900
            :|.|.|....:..::.:|.||...:.:|::.||::...|||:||||.|:..||..||..|...||
 Frog  1002 LRAFLFALGTVHAAVVIHRRLLSSVLQATVSFFDSTPIGRIINRFSSDLYCVDDSLPFVLNIFLA 1066

  Fly   901 FIIDVSGVVIIVAIANYWLLIPAAIIGVILGMIRYLYVNTSRSVKRLESISRSPVFSLTNQTFQG 965
            |...:.|::::::....|:|.....:.::...::..|.::||.:|||:||:.||:::..::|..|
 Frog  1067 FTFGLLGMLVMISYGLPWILPVLLPLCLLYYYLQRFYRHSSRELKRLQSITLSPIYTHFSETLTG 1131

  Fly   966 LTTIRALQAQSALEQEFHEYQNTNTSAWFLFLSCTRAFALWSDV---LCIVYMTAVTFSFLLLKD 1027
            ||||||.:.....|.|.......|....|    .:.|...|.|:   :..|.:.|......:::.
 Frog  1132 LTTIRATRHADRFEAECVSRLEVNQRCMF----ASNAAVQWLDIRLQMIGVMVVAAISVIAIIQH 1192

  Fly  1028 EFDSGD---VGLAILHSTTMTGMCQWGMRQTAELENQMTSVERVLEY-TEQPSEALLETPEKFKP 1088
            :..|||   ||||:.::.::||:....:....:.|..|.||||..|| |..|||:   .....:.
 Frog  1193 QRKSGDPGLVGLALSYALSITGILSGLISSFTQTEAMMVSVERTEEYSTTLPSES---AEGSLQV 1254

  Fly  1089 KSEWPSKGRIEFINFKLRYSPKEAPVLKDLNFTIEPREKIGIVGRTGAGKSSIIQSIFR-LACNE 1152
            :.:||:.|.|||.|..|.|.......|..::|||.|.||||||||||:|||::..::|| :...|
 Frog  1255 ELDWPTNGHIEFRNVVLCYRLGLPNALDGISFTISPGEKIGIVGRTGSGKSTLFLALFRMMELKE 1319

  Fly  1153 GMIRIDDVDIEHIGLHDLRSQVSIIPQDPVLFSGTLRYNLDPMDERSDEEMWKALGDVELRSYVS 1217
            |.|.||:|....:.|..|||:::|||||..||||::|.||||:...:|.|:.|.|....|:..|.
 Frog  1320 GSILIDNVPSHLLNLELLRSRLAIIPQDAFLFSGSVRVNLDPLSYHTDVEILKVLDQCHLQDVVR 1384

  Fly  1218 TLIGGLNCRMYDGGSNFSVGQRQLVCLARAILRHNKILIMDEATANVDPETDKLIQQTIRSKFAH 1282
            . ||||:..:.|.|.|||:|||||:|||||:|.|.|||.:|||||:||.:||:|:|:|||.:|..
 Frog  1385 R-IGGLDADVGDRGKNFSLGQRQLLCLARALLTHAKILCIDEATASVDHQTDELLQRTIRERFRE 1448

  Fly  1283 CTVLTIAHRLHTVMDSDRVLVMDAGEVRELGHPYELLQRTGGYLRQLV 1330
            .|||||||||:|:|||||||||.||::.||..|..|.:|......:|:
 Frog  1449 RTVLTIAHRLNTIMDSDRVLVMHAGKLVELDSPANLSKREDSNFYRLI 1496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rdog	NP_651678.1	MRP_assoc_pro	14..1323	CDD:188098	434/1339 (32%)
abcc10	NP_001135594.1	MRP_assoc_pro	180..1484	CDD:188098	432/1334 (32%)